Covid-19 Vaccine Development

[CrimeAway]

INO, i would hope that provision can be made for allergic individuals to have the vaccine in a hospital or other setting with immediate access to resuscitation in the rare event that it is needed.

 

[IceIce9]

INO, i would hope that provision can be made for allergic individuals to have the vaccine in a hospital or other setting with immediate access to resuscitation in the rare event that it is needed.

When we give any vaccine, we ask the patient to wait 15 minutes before leaving in case they have any type of reaction. And injections of any kind should not be given unless emergency meds and equipment is available, as well as trained personnel.

 

[IceIce9]

FWIW, a friend is a senior scientist at Pfizer. He says that he will be one of the first to get the vaccine, and he wants his family members to get it as soon as it is available for the general public.

 

[dixiegirl1035]

DBM - moved to main thread oopsie

 

[CSIDreamer]

FWIW, a friend is a senior scientist at Pfizer. He says that he will be one of the first to get the vaccine, and he wants his family members to get it as soon as it is available for the general public.

That's actually comforting and good info. I'm way down the list though. Jmo

 

[dixiegirl1035]

DBM - moved to main thread oopsie

 

[margarita25]

Sanofi and GlaxoSmithKline delay plans for a trial after experimental vaccine fails in some older patients.

“The pharmaceutical companies Sanofi and GlaxoSmithKline said Friday that their experimental Covid-19 vaccine did not appear to work well in older adults, a significant setback to their late-stage clinical trial that was previously expected to begin in the United States in December.

Instead, the companies said they planned to test a modified version of their vaccine in a smaller trial beginning in February. Rather than compare their candidate with a placebo, they said, it could be tested against a vaccine expected to be authorized by regulators for emergency use soon.

The Sanofi vaccine is one of six that were selected by Operation Warp Speed, the federal government’s effort to quickly bring a vaccine to market. The companies negotiated a $2.1 billion agreement with the United States to provide 100 million doses.“

 

[margarita25]

Australia scraps a Covid-19 vaccine that produced H.I.V. false positives.

“Australia on Friday canceled a roughly $750 million plan for a large order of a locally developed coronavirus vaccine after the inoculation produced false positive test results for H.I.V. in some volunteers participating in a trial study.“

-more at link

 

[margarita25]

More governments set up vaccine deals, and other news around the world.

“Hong Kong and Japan announced on Friday that they had secured vaccines for their citizens, while Saudi Arabia said on Thursday it had approved one for use, as governments worldwide line up for vaccines rapidly becoming available.

The chief executive of Hong Kong, Carrie Lam, said on Fridaythat the Chinese territory had struck an agreement to buy 15 million doses of coronavirus vaccines. Half will come from Sinovac — whose unproven vaccine has already been given to tens of thousands on the Chinese mainland — and the other half from Pfizer-BioNTech.“

[...]

“Japan has also agreed to buy 120 million doses of the Pfizer-BioNTech vaccine and 50 million doses of the Moderna vaccine.“

 

[margarita25]

Testing times: More work needed on Astra/Oxford vaccine trials
DECEMBER 8, 2020

 

[BetteDavisEyes]

The possibility of allergic reactions to the Pfizer vaccine is concerning. Unless they've been tested and are aware of environmental and/or food allergies, many people aren't even aware that they have allergies until they experience an allergic reaction. Allergies to medications aren't generally known until one has a reaction to a drug. I had a severe reaction to a sulfa medication for a UTI that sent me to the ER with hives and swollen tongue. Prior to the episode, I had no idea that I was allergic to sulfa. I realize that people are anxious to be vaccinated against this deadly virus, but rushing the vaccine/s to market without careful analysis of side effects and/or allergic reactions would be counterproductive. MOO

 

[RANCH]

FBI warns scammers will offer way to get vaccine fast for a fee

With a vaccine close at hand, the FBI is now warning people to be aware of vaccine-related scams.

The Federal Trade Commission said you likely won't need to pay anything out of pocket to get the vaccine during the public health emergency. You can't pay for early access, and you can't pay to put your name on a list to get the vaccine.

FBI warns scammers will offer way to get vaccine fast for a fee

 

[IceIce9]

The possibility of allergic reactions to the Pfizer vaccine is concerning. Unless they've been tested and are aware of environmental and/or food allergies, many people aren't even aware that they have allergies until they experience an allergic reaction. Allergies to medications aren't generally known until one has a reaction to a drug. I had a severe reaction to a sulfa medication for a UTI that sent me to the ER with hives and swollen tongue. Prior to the episode, I had no idea that I was allergic to sulfa. I realize that people are anxious to be vaccinated against this deadly virus, but rushing the vaccine/s to market without careful analysis of side effects and/or allergic reactions would be counterproductive. MOO

Both of the people who suffered allergic reactions to the COVID vaccine had severe allergies to the point that they carried Epi pens with them.

 

[margarita25]

2 new vaccine-related threads on WS:

Vaccine Poll::
Would you get it?

Members' Covid-19 Post-Vaccination Questions & Answers *NO GENERAL DISCUSSION*

 

[margarita25]

Dr. Fauci debunks myths

 

[dixiegirl1035]

The possibility of allergic reactions to the Pfizer vaccine is concerning. Unless they've been tested and are aware of environmental and/or food allergies, many people aren't even aware that they have allergies until they experience an allergic reaction. Allergies to medications aren't generally known until one has a reaction to a drug. I had a severe reaction to a sulfa medication for a UTI that sent me to the ER with hives and swollen tongue. Prior to the episode, I had no idea that I was allergic to sulfa. I realize that people are anxious to be vaccinated against this deadly virus, but rushing the vaccine/s to market without careful analysis of side effects and/or allergic reactions would be counterproductive. MOO

Since I first heard of this, and that they carried epi pens - I was wondering if they could have had known allergy to latex (or unknown). This am, just did a google search and YES, there is such a thing not only for the latex gloves (vs. nitrile standards nowadays) and the latex or rubber of the syringe and stopper on the vial.

Vaccine-associated hypersensitivity

ACIP Adverse Reactions Guidelines for Immunization | Recommendations | CDC

International Consensus (ICON): allergic reactions to vaccines | World Allergy Organization Journal | Full Text
International Consensus (ICON): allergic reactions to vaccines

VAERS | Vaccine Safety | CDC
The Vaccine Adverse Event Reporting System (VAERS) is a national vaccine safety surveillance program run by CDC and the Food and Drug Administration (FDA). VAERS serves as an early warning system to detect possible safety issues with U.S. vaccines by collecting information about adverse events (possible side effects or health problems) that occur after vaccination.

VAERS was created in 1990 in response to the National Childhood Vaccine Injury Act. If any health problem happens after vaccination, anyone – doctors, nurses, vaccine manufacturers, and any member of the general public – can submit a report to VAERS.

Safety Information by Vaccine | CDC
Safety Information by Vaccine
Get the latest safety information from CDC on recommended U.S. vaccines – safety studies, common side effects, vaccine information statements and more.

https://www.cdc.gov/vaccines/pubs/pinkbook/downloads/appendices/B/excipient-table-2.pdf
List of all approved vaccines in the US and their ingredient breakdown

 

[BetteDavisEyes]

Delivery of first Covid-19 vaccines expected Monday (nbcnews.com)

About 2.9 million doses of the vaccine are expected to be shipped within the first week.

Hospital systems nationwide should expect the first shipments of Pfizer's Covid-19 vaccine to arrive Monday, Gen. Gustave Perna, chief operating officer of Operation Warp Speed, said during a media briefing Saturday.

"Boxes are being packed and loaded with vaccine with emphasis on quality control," Perna said. Within the next 24 hours, he said, those boxes will move from Pfizer's manufacturing facility to UPS and FedEx hubs, where they will be delivered to 636 predetermined locations nationwide...

 

[Betty P]

Looks like the Moderna vaccine is up for it's FDA review next week.

200 million doses of the Moderna vaccine have been ordered, it requires 2 doses

Moderna’s vaccine, which is based on messenger RNA technology and about 95 percent effective in trials, will be discussed by an expert FDA panel on Thursday. Emergency authorization could come within days, potentially making the shot the second vaccine cleared for use in the United States.

Trump administration buying another 100 million doses of Moderna's COVID-19 vaccine

 

[Betty P]

Delivery of first Covid-19 vaccines expected Monday (nbcnews.com)

About 2.9 million doses of the vaccine are expected to be shipped within the first week.

Hospital systems nationwide should expect the first shipments of Pfizer's Covid-19 vaccine to arrive Monday, Gen. Gustave Perna, chief operating officer of Operation Warp Speed, said during a media briefing Saturday.

"Boxes are being packed and loaded with vaccine with emphasis on quality control," Perna said. Within the next 24 hours, he said, those boxes will move from Pfizer's manufacturing facility to UPS and FedEx hubs, where they will be delivered to 636 predetermined locations nationwide...

I'm so glad the front line health care workers will be getting the vaccine soon. What they do every day is so risky, I can't imagine. My SIL is a nurse working with the elderly and the precautions they take, the scares, the stress is terrible.

 

[IceIce9]

.

• Dr. Archana Chatterjee told CNBC on Friday she voted against recommending emergency use authorization for Pfizer's Covid-19 vaccine because she did not believe 16- and 17-year-olds should be included.
• "I want to be very clear that I am fully supportive" of clearing the vaccine for use in people 18 years and older, the dean of the Chicago Medical School said.
• "I think that we were pleasantly surprised to see that this vaccine has such good efficacy in tens of thousands of participants that were included in the trial," Chatterjee said.

FDA advisor explains why she voted against recommending Pfizer's Covid vaccine for emergency use