High profile cases creates tremendous pressure on LE and the D.A.s office. My experience is that what they both want to do is lessen the pressure on themselves, so they will happily throw someone to the crimetainment wolf pack based on but minor particles of evidence or just a suspicion. And they do not have to arrest someone to ruin their lives. The experience of being wrongfully demonized by the media does a superb job of that.
I could list high-profile case after high-profile case where there was wrongful demonization and/or a wrongful conviction or, sometimes, a likely wrongful acquittal (often a result of celebrity justice). When a case is goes under the floodlights, my experience is that it's a great environment for bad things to happen, especially in our rush-to-judgment culture.
As for framing, just remember that most every wrongful conviction represents a framing. Sometimes it's a passive framing, because the person who truly committed the crime does not step forward. And sometimes D.A.s frame people by withholding exculpatory evidence from the defense -- 999 times out of a 1,000, nothing will happen to them. Moreover, LE has certainly been known to manufacture false evidence and use it to convict people, but I'm sure you know that.
