Let me see if I can (subtly) shine some light here.
I know a
little about S&M/D&S/BDSM, etc...
Most people in the lifestyle that I know wouldn't dare touch drugs and especially not during role play. They are very adamant about safe, sane and consensual. There is no place in the lifestyle for drugs. There are plenty of dangers if a Dominant were on drugs and hurt the submissive and this isn't something they take lightly.
I'm speaking of a true lifestyler. I can't speak for the wannabe's that have no idea about "safe" role play.
Did that help?
ETA: I know if you google chloroform/sex, you'll come up with some bizarre things. But just because it is googlable it doesn't make it a majority rule.