I used to travel a lot for business and still travel solo to Florida many times, there and back. As a female and traveling alone you learn there are ways to bolster safety while in unfamiliar places. Never stay in a ground floor room. Don't take a room close to a stair exit. Park as close to the front entrance as possible not near a side door to the building, even though you may have to walk further to your room.
I've had to have 'the talk' with random hotel desk clerks, many female to my dismay, who seem to think it's okay to verbalize the information on my driver's license, letting everybody waiting in line know where I'm from, what car I drive, my name and the room number I've just been given. I try to tell them the reason I gave them the license in hand is to keep my info confidential, not broadcast it to all and sundry.
You'd think there was some kind of standard process in all hotels to ensure safety for their female travelers but you'd be surprised how many places I've gone to that don't seem too concerned about it and get miffed when you point it out.
Because I have a long and complicated last name I always give an alias when making reservations at restaurants, etc.