http://www.acandyrose.com/1997BPD-Patsy-Interview-Complete.htm
TT: Okay. Patsy, I need to go through a couple of things here. What medications are you on right now? Are you still on Paxel?
PR: Im on Paxel, um hum.
TT: How often do you take that?
PR: In the evenings (inaudible) once a day.
TT: Just a bedtime?
PR: Um hum.
TT: And, whats the dose on that?
PR: 30 milligrams.
TT: And, are you taking anything else right now?
PR: I just started Monday taking something for this sinus infection. I know your going to ask me the name of it.
TT: Is it an over the, Ill start (inaudible).
PR: No, its a prescription.
TT: Okay.
PR: You take it once a day for five days. Dr. Beuf prescribed it.
TT: Okay. And, are you taking anything else right now?
PR: Um, no.
TT: Any over the counter medication, vitamins . . .
PR: Vitamins. Im taking vitamin C.
TT: Okay.
PR: (Inaudible) vitamin C.
TT: Just for that sinus infection?
PR: Right.
TT: Is that an ongoing type or just . . .
PR: Well, I just. . .
TT: (Inaudible)
PR: I just, since Monday started taking a lot of it.
TT: Okay. Okay. Um, any, any other uh, any other drugs, originally you were taking Paxel and what was the other drug you were taking? Lorzipan.
PR: Ah yeah, right.
TT: Are you still taking that at all?
PR: Uh, occasionally. Kind of as, on an as needed basis.
TT: When was the last time you took the Lorizpan?
PR: Uh, I took one last night about 6:30.
TT: Hows that, hows that one make you feel. I mean, out of the two do any of them effect you at all that you can notice?
PR: I mean I dont really notice anything, but I, usually I take the Adavan if Im, I start getting, evenings are difficult for me.
TT: Um hum.
PR: When I start getting tired and I feel the onset of this, not feeling real good. Last night I was pretty, I just been missing JonBenet a lot lately.
TT: Okay.
PR: And uh, you know, it, it seems to, to kind of quell that . . .
TT: Takes the edge off a little bit.
PR: Takes the edge off a little bit.
TT: What kind of dose are you taking on the Adavan when you take it?
PR: Uh, a half milligram.
TT: Okay. Took it last night, how, about how many times a week are you taking that? Once, twice?
PR: Well, probably a couple.
TT: A couple of times a week is all?
PR: Yeah.
TT: Okay. The Adavan and the Paxel, um . . .
PR: The Paxel is an anti-depressant.
TT: Um hum. Either one of them, do you think either one of thems kind of, uh, changing your thought process or clouding your mind, memory, anything like that?
PR: No.
TT: Okay. Its not, not effecting any judgment or anything like that?
PR: No, huh uh.
TT: Okay. Um, I all this, I know with the sinus infection your probably not even thinking about it, um, have you taken any alcohol? How much alcohol . . .
PR: No. I dont drink alcohol.
TT: Okay. Uh, do you drink alcohol at all?
PR: No. Not since Ive been on the Paxel at all.
I wonder if Patsy was taking the Lorazepam/Adavan prior to JBRs death? Maybe given while she battled cancer. It would give a great explanation for what took place that night. Just as it explains her confusion in her interviews.... Ive posted a snip of the 1997 BPD interview at the top, below I have snip from Wiki, about Lorazepam and the link too the source.....
http://en.wikipedia.org/wiki/Lorazepam
Lorazepam (initially marketed under the brand names Ativan and Temesta) is a high potency benzodiazepine drug which has all five intrinsic benzodiazepine effects: anxiolytic, amnesic, sedative/hypnotic, anticonvulsant and muscle relaxant.[4][5] Lorazepam is used for the short-term treatment of anxiety, insomnia, acute seizures including status epilepticus and sedation of hospitalised patients, as well as sedation of aggressive patients.[5][6][7][8]
Lorazepam is considered to be a short-acting drug which, similar to other benzodiazepines, exerts its therapeutic as well as adverse effects via its interaction at benzodiazepine binding sites, which are located on GABAA receptors in the central nervous system. After its introduction in 1977, lorazepam's principal use was in treating anxiety. Among benzodiazepines, lorazepam has a relatively high addictive potential.[4][9] Lorazepam also has abuse potential; the main types of misuse are for recreational purposes or continued use against medical advice.[10] The sedative-hypnotic and anterograde amnesia properties of lorazepam are sometimes used for criminal purposes.[11][12]
Long-term effects of benzodiazepines include tolerance, dependence, a benzodiazepine withdrawal syndrome and cognitive impairments which may not completely reverse after cessation of treatment; however, for most patients, cognitive impairment is not severe. Withdrawal symptoms can range from anxiety and insomnia to seizures and psychosis. Due to tolerance and dependence, lorazepam is recommended for short-term use, 24 weeks only. Adverse effects including anterograde amnesia, depression and paradoxical effects such as excitement or worsening of seizures may occur. Children and the elderly are more sensitive to the adverse effects of benzodiazepines.[4][13][14] Lorazepam impairs body balance and standing steadiness and is associated with falls and hip fractures in the elderly.[15]
Adverse effects
Any of the five intrinsic benzodiazepine effects possessed by lorazepam (sedative/hypnotic, muscle relaxant, anxiolytic, amnesic, and anticonvulsant) may be considered as "adverse effects," or "side effects," if unwanted.[5] Adverse effects can include, ataxia, sedation and hypotension; the effects of lorazepam are increased in combination with other CNS depressant drugs.[7][8] Other adverse effects include confusion, ataxia, anterograde amnesia and hangover effects. With long-term use of benzodiazepines it is unclear whether cognitive impairments fully return to normal after cessation of therapy; cognitive deficits persist for at least 6 months post-withdrawal, but it is possible that longer than 6 months is required for recovery of cognitive function. Lorazepam appears to have more profound adverse effects on memory than other benzodiazepines; lorazepam impairs both explicit memory and implicit memory. In the elderly, falls may occur as a result of benzodiazepines. Adverse effects are more common in the elderly, and they appear at lower doses than in younger patients. Benzodiazepines can cause or worsen depression. Paradoxical effects can also occur, such as worsening of seizures, or paradoxical excitement; paradoxical excitement is more likely to occur in the elderly, children, those with a history of alcohol abuse and in people with a history of aggression or anger problems.[4] Lorazepam's effects are dose-dependent, meaning the higher the dose, the stronger the effects (and side effects) will be. Using the smallest dose needed to achieve desired effects lessens the risk of adverse effects.
Sedation is the most complained-of side effect. In a group of around 3500 patients treated for anxiety, the most common side effects complained of from lorazepam were sedation (15.9%), dizziness (6.9%), weakness (4.2%), and unsteadiness (3.4%). Side effects such as sedation and unsteadiness increased with age.[42] Cognitive impairment, behavioural disinhibition and respiratory depression as well as hypotension may also occur.[23][33]
Paradoxical effects: In some cases, there can be paradoxical effects with benzodiazepines, such as increased hostility, aggression, angry outbursts, and psychomotor agitation. These effects are seen as more common with lorazepam than other benzodiazepines.[43] Paradoxical effects are more likely to occur with higher doses, in patients with pre-existing personality disorders and those with a psychiatric illness. It is worth noting that frustrating stimuli may trigger such reactions, even though the drug may have been prescribed to help the patient cope with such stress and frustration in the first place. As paradoxical effects appear to be dose-related, they usually subside on dose reduction or on complete withdrawal of lorazepam.[44][45][46][11][47][48]
Suicidality: Benzodiazepines may sometimes unmask suicidal ideation in depressed patients, possibly through disinhibition or fear reduction. The concern is that, though relatively nontoxic in themselves[verification needed], benzodiazepines may inadvertently become facilitators of suicidal behaviour.[49] Lorazepam should, therefore, not be prescribed in high doses or as the sole treatment in depression, but only with an appropriate antidepressant[specify].
Amnesic effects: Among benzodiazepines, lorazepam has relatively strong amnesic effects,[5][50] but patients soon develop tolerance to this with regular use. To avoid amnesia (or excess sedation) being a problem, the initial total daily lorazepam dose should not exceed 2 mg. This also applies to use for night sedation. Five participants in a sleep study were prescribed lorazepam 4 mg at night, and the next evening three subjects unexpectedly volunteered memory gaps for parts of that day, an effect that subsided completely after 23 days' use.[51] Amnesic effects cannot be estimated from the degree of sedation present, since the two effects are unrelated.
High dose or prolonged parentally administered lorazepam is sometimes associated with propylene glycol intoxication.[23][52]
Full lists of Lorazepam side effects:
For lists of lorazepam side effects, refer to the manufacturers' data sheets. Please note that some may list side effects for the entire benzodiazepine class, not the specific side effect profile for lorazepam.
You really should read about this drug... My guess is, PR was given this when she was dealing with the cancer. Mentally fragile suffering from DID. PR had been through massive amounts of chemo. Keep in mind this was just an experimental treatment, no one knows what side effects it had at the time (curious to know, what they know now) and chemo has been known to effect the mind (not on all people). When given this serious drug and possibly becoming addicted.... Well, you can see where I'm going with this. Please remember this is just an opinion and a theory.
