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Maybe Manuela Comodi thinks that she knows more about testing for blood than forensic scientists do, but forensic scientists are quite clear about the need for a true confirmatory test to be performed, and yet no confirmatory tests were performed on the footprints in the hallway. Rusty water (iron), plant matter of any kind (manganese, iron, copper, and probably a trace of cobalt), and soil are but three places where transition metal ions may be found. Gregory Taylor was convicted partially on the basis of a presumptive blood test, but eventually he was released when it was learned that confirmatory tests were negative, yet the results had been hidden. A misunderstanding of the limitiations of presumptive blood testing is a problem in many jurisdictions (I have previously discussed the Lindy Chamberlain case in this regard).
Let's suppose that we leave the bloody footprints in the hallway matching Knox on the sidelines for now. We still have Knox's DNA and Meredith's blood in Filomina's bedroom. How is that explained?