I know the area where this girl was abducted extremely well. My father attended high school in Dumas, Ark. and his sister & her husband still live there. I grew up in Desha County.
I've seen reports that her car was on the south side of Dumas on US 65 (still a 2 lane highway that cuts through vast farmland) yet also that it was 200 yards away from the hospital and an Exxon station. Unless they've built a new one, the hospital is on the North side of town. And the Exxon there isn't 24 hours.
Pickens is on the south side of Dumas--it's actually an old plantation that kind of grew a small community of less than 100 people around it. It's a fairly affluent community, though, as those things go in that part of the state.
If she was headed towards Dumas from Pickens on US 65, she would have to drive pass a used tractor & car lot, the old Sunbeam Appliance plant (where they use to make toasters and mixers), the abandoned Winn-Dixie/Dixie Dandy store, a large strip mall that has (or use to have) a movie theater, a TG&Y, a pizza place & a florist; the Wal-Mart, the Mad Butcher grocery store, the McDonalds, a Sonic and a Best Western motel.
The north end of town is a lot dicier, as it abutts "Mitchellville", what is referred to as a gin-town--a community that grew up around the local cotton gin and rice dryer. It's composed of almost entirely Afrcan Americas & Mexicans, and has a LOT of gangbanging given that the Dumas metro is probably 5000 people, tops. There is a 24 hour truck plaza in Mitchellville right on 65, but I forget what it is--I'm fairly sure its Shamrock or Chevron.
The next community from Pickens headed south on 65 is Winchester, which has under 200 people and is 7 miles from Pickens. The next community after that is Tillar, which has under 300 people, and is 7 miles from Winchester. Both Winchester & Tilllar are actually in Drew County. The next town after Tillar is McGehee, which is about 10 miles away and has around 4000 people and is located in Desha County (the counties are mapped out weird).
To the North of Dumas I beleive the next community is either Grady or Gould.
This is where nearly all the guards and other civilians who work at Cummins Prison Farm live. Cummins Prison Farm is about 20 miles from Dumas. There are signs scattered all along that stretch of 65 that say "Don't Pick Up Hitchhikers!"
Although news reports describe 65 as "busy", that's only during the day. After 10pm the highway is practically deserted except for 18 wheelers. It's a rural area, flat as a pancake, and darker than a grave once you get away from town lights. Due to the poverty in that part of the state, the criminals tend to be exceptionally vicious & brutal. It's definitely Jim Thompson, Joe Lansdale territory.