@evangelicsphere , do you/your Mom have a copy of her birth certificate, the older the better? Most states have a way to order a copy of the
complete form. (It's likely a scan today.) If you order a new birth certificate, there won't be much information on, just the legal minimum. A long form certificate and possibly the hospital certificate (not a legal document, but often pretty & frame-worthy) will provide some information.
A copy of the
marriage license may help. Your missing Grandma's parents will be listed, and the witnesses were probably your parents' closest friends at the time. Those folks may have information to help you.
With the license, you visit or surf newspaper archives for the weeks before & after, looking for announcements & other information.
Was your Mom christened or baptized? The baptismal certificate will again list friends & give us a set point in time. And, a place in a group with newsletters, records, and archives.
Where did Grandma go to school? Many high schools/graduating classes have Facebook pages. You may be able to post her name & picture and have a quick response.
LotsaLatte, too much work & holiday right now, not even time to try FamilySearch; maybe after Christmas?
If your Mom is interested in genealogy, these steps will either be familiar to her or things she needs to know how to do! She should try the USGenWeb website for the county of her birth, too.
23&Me and Ancestry submission will help.
@LotsaLatte & I grab these genealogy-heavy situations & run! But -- we're
not kin, you & your Mom will need to request documents.