One way or another, yes.
From what I've read, the most common reason a victim's clothes are found neatly folded is that the perp forced the victim to disrobe. The victim draws it out by neatly folding each article of clothing because they know that what is likely to happen next will be worse than being forced to undress.
So if a victim's clothes are found neatly folded by the victim, it indicates that the crime was taking place somewhere the perp felt safe and could take his time. It may also indicate that the perp was enjoying the victim's fear (and possible shame), which may mean the perp is sadistic in nature.
If the perp folded the clothing neatly, it may indicate he felt some sense of remorse after the fact. Or he may be a methodical person who was carefully tracking each piece of potential evidence that he wanted to be sure did not get left somewhere that would incriminate him.
There are probably other things that can be inferred; those were just the top two.