Coronavirus COVID-19 - Global Health Pandemic #50

[oviedo]

<modsnip: quoted post was removed> I did get a flu shot this year - which I normally don't - maybe one other time? and as many of you know, I went on the last sailing of a RCCL ship in March - we were told on Sunday that it was going to be the last one for awhile. I'm around young and old at work - many who didn't (and still don't) think this is anything more than a cold - and only began to take it seriously when they couldn't get TP - and saw grocery stores limiting food quantities and then the restaurants closed to dining - so they go out every day - grocery, fast food - take out, etc. I'm exposed constantly to whatever germs they bring in - I wonder if my flu shot is protecting me somehow??? I only go to the grocery when I absolutely have to (using a mask, gloves, hand sanitizer, etc) and one splurge of take out dinner since returning from the cruise 6 weeks ago. If I get it- it will be from one of them who brings it to the office from their daily trips out- no remote work allowed. sigh.
JMO

 

[Deleted member 158085]

https://www.washingtonpost.com/us-p...wMmt2AOv3LIKUxr098eL6Ul5SYPejiT3IrK4MZguOSG88

President Trump said Friday he would not approve an emergency loan for the U.S. Postal Service if it did not immediately raise its prices for package delivery, confirming a recent Washington Post report that said he planned to exert more control over the agency.

Look how long it is taking for shipping right now. Now consider how long it’s going to take if we let one of the big 3 fail. UPS and FedEx cannot pick up the slack. We need shipping now more than ever.

 

[rodneymullenmg]

Look how long it is taking for shipping right now. Now consider how long it’s going to take if we let one of the big 3 fail. UPS and FedEx cannot pick up the slack. We need shipping now more than ever.

With the economy how it is, and people needing the post office. Why is blackmailing them into raising the prices needed right now?

I dont understand

 

[Deleted member 158085]

I got a good chuckle out of reading a link PommyMommy provided that said

Japanese mayor says men should grocery shop during coronavirus pandemic as women 'take a longer time' - CNN

Some quotes:


It is the opposite in my household. My dh likes to whip out his phone to calculate the unit prices in deciding which item is a better buy. He’s a smart shopper, but it makes me crazy sometimes when I just wanna buy what I wanna buy!

Same here, although I don’t think that’s the reason it takes my husband longer. He just dilly dallies.

 

[LadyL]

An attack last month in East Vancouver that police say was racist has shone a light on not just the challenges people of Asian descent face during the COVID-19 pandemic, but also on the unresolved racism simmering in society.

Assault on elderly man in Vancouver a hate crime: VPD

 

[10ofRods]

Anyone know results of ozone generators? I have two. I've read they do kill the virus if used in infected rooms. tia

...and yes, they are dangerous for people but kill the germ and stay away for a while. imo

Yes, if there's no one in the room, the room can be sterilized with ozone. It's effective against HIV and many other pathogens, and is likely effective against CoVid.

However, the minute an infected person enters the room, it's back again. And of course, it's dangerous for a human to inhale it. There are apparently drugs that capture the ozone effect and can be used orally (and have been used in some studies for other diseases) but there are risks.

It's bad for the lungs if you breathe it, so some experiments have been done with a patient in oxygen masks in order to sterilize what they're wearing and the rest of the room. Not sure what value that would have in this case, as the room would have to be returned to its regular state for any medical personnel to go in.

Ozone therapy: A clinical review

I think this article also says that one inhalation of O3 (ozone) before the administration of the drug that mimics its action had good effects on COPD and Cystic Fibrosis (neither is viral of course). There don't seem to be a lot of follow up studies nor is it widely in use. The O3 used in all the experiments was based off of pure oxygen (hospital oxygen), not the oxygen in our atmosphere.

 

[Reasonable & Just]

This is great! Its so hard to communicate with these on. So many nuances go unnoticed.

Great story

That's wild, and not something I would have thought of. I am so glad someone did, and it seriously is brightening a dark day to hear about the good works of smart, thoughtful people.

 

[cass523]

Over 50 kids in the Silverlake Conservatory of Music Choir virtually came together to sing Bowie’s “Space Oddity.”

With school and pretty much all activities on hold indefinitely due to shelter at home orders over #COVID-19, students of the Silver Lake Conservatory of Music were not going to be silenced!

They were sent by their conservatory choir cirector the music and lyrics to David Bowie’s iconic Space Odyssey on Friday, April 17, 2020. Then they recorded this on Monday, April 20, 2020.

Nearly all the students in the choir are local to the area and attend schools like Marshall High School and Thomas Starr King Middle School.

We thought it was pretty great and hope you do too.

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[Tadpole12]

You are right in the mental effects on older people. I live in my home, but stay at home. I find myself bursting into tears just reading news and posts on WS, I don't have an appetite, so I just pick at anything, even then it doesn't even taste good. I find myself losing my balance a lot now, at first I thought it was my slippers, but now I don't think so, my hands are also getting very shaky, and I find typing on the keyboard results in a lot of double letters in a word. In otherwords, I'm a wreck, I know it and there is nothing I can do about it.

MOO

I wish I knew something you can do about it.

IDK

 

[Herat]

https://www.washingtonpost.com/us-p...wMmt2AOv3LIKUxr098eL6Ul5SYPejiT3IrK4MZguOSG88

President Trump said Friday he would not approve an emergency loan for the U.S. Postal Service if it did not immediately raise its prices for package delivery, confirming a recent Washington Post report that said he planned to exert more control over the agency.

Micromanaging the post office to INCREASE shipping rates when people desperately need USPS to deliver those Amazon packages for things they can't find in their local stores

 

[PommyMommy]

UK will host "Global Vaccines Summit" on June 4

[...]

“Diseases have no borders, so we must come together to make sure that Gavi [The Vaccine Alliance] is fully funded and its expertise is at the heart of efforts to secure broad access to any COVID-19 vaccine,” Raab tweeted.

Gavi is an international organization that aims to bring together the public and private sectors to improve access to vaccines.

In a later tweet, the British foreign secretary added that the UK will also co-host the Coronavirus Global Response Summit on May 4 alongside its international partners, including the European Union, Japan, Saudi Arabia, Norway and South Africa.

“The UK is playing a leading role in efforts to develop a COVID vaccine and better testing. We’re pleased to co-host the Coronavirus Global Response Summit on 4 May with our partners…to develop a vaccine together,” he added.

Coronavirus live news and updates from around the world - CNN

 

[10ofRods]

I wonder how much they are paid. This is a serious risk. We don’t yet know the long-term effects. I’m thinking about things like Epstein Barr and Lyme Disease, which can basically ruin your life. Well, we don’t know if even some of the 20 year olds who seem to fully recover may develop issues later related to this illness.

Your post made me think about how the "fully recovered" number has been surprisingly low in the US. There seem to be plenty of 20 and 30-somethings who have had a very difficult course, still have lung problems, and then there's the data that shows that the "glass-like shards" in the lungs have done damage that is typically irreversible. Naturally, some people experience miraculous recoveries over a lifetime, but most people don't.

These "glass-like shards" are, in my understanding, microscopic and should be visualized as actual glass shards! But doctors have been using those terms to convey the damage they do. They end up in clusters that are visible on x-ray or MRI. It's possible that this is happening in the veins as well (and as circulation is impaired, is responsible for the chilbains and similar skin conditions).

Not everyone gets these, of course. So far, I know of no genomic studies of actual CoVid sufferers, but that surely will happen (and the data is in their blood, so if reference labs or research labs have their blood for other purposes, they can do that soon enough).

The kidneys are taking a real beating from this same viral process (and the liver too, in some people). So, yeah, it remains to be seen if all the younger people who are surviving a serious case will in future have issues. I have a feeling that they're not being classified as "fully recovered" until all systems return to regular functioning and that's verified.

 

[Reasonable & Just]

One more day-brightener before I skedaddle I had never heard of this social practice. Enjoy your weekend, all!

In Italy, 'Suspended Shopping' Helps Those Facing Economic Hardship During Pandemic

 

[katydid23]

Earlier this week, the bio-tech firm Aytu BioScience announced they are partnering with the FDA and Cedars-Sinai on a UV light treatment to kill the coronavirus in intubated patients.

The company released a press release, which is posted here in full (less corporate and disclaimer info at the end):

Aytu BioScience Signs Exclusive Global License with Cedars-Sinai for Potential Coronavirus Treatment

Cedars-Sinai-Developed ‘Healight’ Medical Device Platform Technology Being Studied as a Potential First-in-Class COVID-19 Treatment

Conference Call Scheduled for Tuesday, April 21, 2020 at 4:30 pm ET

ENGLEWOOD, CO / ACCESSWIRE / April 20, 2020 / Aytu BioScience, Inc. (NASDAQ:AYTU) (the “Company”), a specialty pharmaceutical company focused on commercializing novel products that address significant patient needs announced today that it has signed an exclusive worldwide license from Cedars-Sinai to develop and commercialize the Healight Platform Technology (“Healight”). This medical device technology platform, discovered and developed by scientists at Cedars-Sinai, is being studied as a potential first-in-class treatment for coronavirus and other respiratory infections.

The company will host a live conference call and webcast Tuesday, April 21, 2020 at 4:30 p.m. ET. Conference call details are provided at the end of this press release.

Led by Mark Pimentel, MD, the research team of the Medically Associated Science and Technology (MAST) Program at Cedars-Sinai has been developing the patent-pending Healight platform since 2016 and has produced a growing body of scientific evidence demonstrating pre-clinical safety and effectiveness of the technology as an antiviral and antibacterial treatment. The Healight technology employs proprietary methods of administering intermittent ultraviolet (UV) A light via a novel endotracheal medical device. Pre-clinical findings indicate the technology’s significant impact on eradicating a wide range of viruses and bacteria, inclusive of coronavirus. The data have been the basis of discussions with the FDA for a near-term path to enable human use for the potential treatment of coronavirus in intubated patients in the intensive care unit (ICU). Beyond the initial pursuit of a coronavirus ICU indication, additional data suggest broader clinical applications for the technology across a range of viral and bacterial pathogens. This includes bacteria implicated in ventilator associated pneumonia (VAP).

“Our team has shown that administering a specific spectrum of UV-A light can eradicate viruses in infected human cells (including coronavirus) and bacteria in the area while preserving healthy cells,” stated Dr. Pimentel of Cedars-Sinai. Ali Rezaie, MD, one of the inventors of this technology states, “Our lab at Cedars-Sinai has extensively studied the effects of this unique technology on bacteria and viruses. Based on our findings we believe this therapeutic approach has the potential to significantly impact the high morbidity and mortality of coronavirus-infected patients and patients infected with other respiratory pathogens. We are looking forward to partnering with Aytu BioScience to move this technology forward for the benefit of patients all over the world.”

The company believes the Healight platform technology has the potential to positively impact outcomes for critically ill patients infected with coronavirus and severe respiratory infections. The company licensed exclusive worldwide rights to the technology from Cedars-Sinai for all endotracheal and nasopharyngeal indications. Patents have been filed by Cedars-Sinai Department of Technology Transfer, and Aytu BioScience will manage all aspects of intellectual property prosecution and filing globally. Aytu BioScience expects to partner the product outside the U.S.

“We are honored to be partnering with Cedars-Sinai as we believe the Healight therapeutic platform has the potential to help many patients during this coronavirus pandemic and beyond,” said Josh Disbrow, Chairman and CEO of Aytu BioScience.

The Company is engaging with the research team at Cedars-Sinai and the FDA to determine an expedited regulatory process to potentially enable near-term use of the technology initially as a coronavirus intervention for critically ill intubated patients.

Disbrow continued, “This first-in-class technology has the potential to be a game changer for clinicians treating patients infected with coronavirus and other respiratory conditions, and our team is working tirelessly alongside the Cedars-Sinai team to determine the safety and effectiveness of this device in humans.”

 

[Amonet]

There is killing the virus and killing the symptoms of the virus. At present it is the symptoms they are trying to kill, i.e what the body does in response to the virus is what is actually killing people, as I understand it.

In 99.9999% of the population, the immune system is killing the virus in the body, exactly as it should do. For most people that process creates what we know of as the symptoms of the virus. Yes, you're right about that part.

So it's often more about supporting the individual's body through the process of their own immune system fighting the virus, and trying to reduce the adverse effects to the body of the immune response to the virus.

But if you could have something like an antiviral medication that could help your body mop up the virus, then the immune system wouldn't feel the need to create all this inflammation and cell damage that's caused by the response to the virus. I think some of the damage is caused by the virus, but not all of it, a lot of the damage is caused by the body's reponse?

I think it's a very common sense and logical question to wonder if you could 'kill' the virus in the body in order to cure the patient. That's really how we tend to think of medicine, that we take the cure and it destroys the problem that was causing the disease. And most of the time that is a reasonable analogy. But it's not a literal description. It's not like the connection between poison and antidote, for instance, and I think that (poison and antidote) is really more what people expect from medics, that's how they believe they will get cured, and how they wouldn't die of a viral or bacterial infection. And while these are reasonable analogies that we can use in speech (I went to the doctor and he gave me the cure for the disease I was suffering from, and now I'm all better!) that's not a scientific/medical thorough description of what's really going on there. It's good enough in most cases...but at times like this, or in the anti-vax 'debate' it can cause confusion, and I think it can be hard for people who have questions like these and oftentimes they're faced with ridicule and insults, which I don't think helps.

 

[LadyL]

This is great! Its so hard to communicate with these on. So many nuances go unnoticed.

Great story

esp. for those, like me, with hearing issues

 

[PommyMommy]

CDC on Twitter
Household cleaners and disinfectants can cause health problems when not used properly. Follow the instructions on the product label to ensure safe and effective use. Learn more about cleaning and disinfecting your home:
Household Cleaning & Sanitizing

1:47 PM - 24 Apr 2020

Ryan Struyk on Twitter
New CBO projections just out:
- economy in for "sharp contraction"
- Q2 GDP annual rate down 40%
- Unemployment rate at 14% in Q2
- 2020 deficit at $3.7 trillion
- National debt to top 100% GDP
2:20 PM - 24 Apr 2020

CBS News PR on Twitter
Sunday on @FaceTheNation: @margbrennan's interviews with Maryland's @GovLarryHogan, SF Mayor @LondonBreed, @ScottGottliebMD, @BankofAmerica CEO Brian Moynihan, and $IAC Chair and @ExpediaGroup Chair Barry Diller.
Trump impeachment inquiry latest: This week on "Face the Nation," December 15, 2019: Graham, Durbin - CBS News
1:17 PM - 24 Apr 2020

 

[LadyL]

we already know this ... but more comfirmation

Nearly All Patients Hospitalized With Covid-19 Had Chronic Health Issues, Study Finds

Nearly All Patients Hospitalized With Covid-19 Had Chronic Health Issues, Study Finds

 

[LadyL]

One more day-brightener before I skedaddle I had never heard of this social practice. Enjoy your weekend, all!

In Italy, 'Suspended Shopping' Helps Those Facing Economic Hardship During Pandemic

Awesome!!

 

[Deleted member 158085]

esp. for those, like me, with hearing issues

Me, too. I’ve already been thinking about the additional difficulty I will have trying to hear people behind masks when I go back to work.