Coronavirus COVID-19 - Global Health Pandemic #56

[Sundog]

DBM

 

[Sundog]

Studies see ‘no benefit’ in hydroxychloroquine treatment for Covid-19 patients

The evidence keeps stacking up.

Hydroxychloroquine Fails to Help Coronavirus Patients in Largest Study of the Drug to Date

Hydroxychloroquine fails to help hospitalized coronavirus patients in US funded study

Luckily there are other drugs that are being studied which may be more promising in the long run. <modsnip>

Fauci is now doing a clinical trial with hydroxycholoroquine at the National Institutes of Health. If it wasn't promising, the NIH wouldn't put money into a clinical research study.

 

[jjenny]

Fauci is now doing a clinical trial with hydroxycholoroquine at the National Institutes of Health. If it wasn't promising, the NIH wouldn't put money into a clinical research study.

Clinical trials are being done to figure out if something is promising (efficient) or not. Lots of clinical trials fail. So the idea that you only do clinical trials on something that will work doesn't hold water.

 

[gngr~snap]

This vaccine doesn't even work that well against TB. It also doesn't work very well in adults against TB. How do they expect it to work against covid, especially considering most victims are older?
"BCG vaccination is rarely given to anyone over the age of 16 because it does not work very well in adults."
BCG tuberculosis (TB) vaccine overview

IMO it is because of the extremely old (over 100 age group) that are getting Covid-19 and surviving.
They must be wondering was it the BCG they got around 1921.

History of the BCG Vaccine - Calmette, Guerin, Lubeck - TBFacts

 

[jjenny]

IMO it is because of the extremely old (over 100 age group) that are getting Covid-19 and surviving.
They must be wondering was it the BCG they got around 1921.

History of the BCG Vaccine - Calmette, Guerin, Lubeck - TBFacts

There are not that many extremely old people over a 100 year old. If they made it to that advanced age, they presumably have good genes. I really doubt it had anything to do with BCG vaccine.

 

[gngr~snap]

There are not that many extremely old people over a 100 year old. If they made it to that advanced age, they presumably have good genes. I really doubt it had anything to do with BCG vaccine.

17 of the Oldest People in the World to Have Beaten COVID-19

New Jersey woman, 108, among world's oldest coronavirus survivors
For reference for those over 100.
There are several more.

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)31025-4/fulltext

 

[Sundog]

And makes me wonder, why we haven't encourages an age based stay at home policy more aggressively.

This article from the AARP talks about some ways that older people in the workforce with health conditions that make them more susceptible to serious complications from COVID-19 infection and have an increased vulnerability to coronavirus. The lawyers who are quoted suggest that it may be possible to continue teleworking as a reasonable accommodation under the Americans with Disabilities Act. Worth pursuing more on this.
What Are Workers' Rights During a Pandemic?

 

[mickey2942]

Clinical trials are being done to figure out if something is promising (efficient) or not. Lots of clinical trials fail. So the idea that you only do clinical trials on something that will work doesn't hold water.

Unless you start with a flawed hypothesis. Studies can be manipulated in so many different ways. Even the data can be plugged into a different model, and make any outcome "look" statistically significant.

The real test, is when someone who has no financial or political agenda, tries to replicate the model, and finds it to be junk. That is when we see the rest of the story.

 

[firebird]

Scratching Hawaii off my list. Geeze.

New York City man arrested in Hawaii after posting beach photos on Instagram

"Authorities became aware of his social media posts from citizens who saw posts of him — on the beach with a surfboard, sunbathing, and walking around Waikiki at night," reads the release. "This morning agents were able to confirm with hotel personnel that had seen Peters leave his room and the premises on numerous occasions this week."

"He was arrested and booked on Friday, and his bail has been set at $4,000."

"Hawaii Attorney General Clare Connor said, "We appreciate the assistance of local people who spot flagrant violations of our emergency rules on various social media sites and report them to the appropriate authorities."

"Hawaii now requires tourists to list their contact and lodging information, and sign an agreement for 14 days of self-quarantine. "By signing the legal document, they acknowledge they understand violating the order is a criminal offense and they are subject to a $5,000 fine and/or a year imprisonment," according to the state's department of transportation."

 

[gngr~snap]

Fauci is now doing a clinical trial with hydroxycholoroquine at the National Institutes of Health. If it wasn't promising, the NIH wouldn't put money into a clinical research study.

They must be researching it as a preventative or ar a lower dose.
Interesting!
Moo

 

[TMAN2014]

Scratching Hawaii off my list. Geeze.

New York City man arrested in Hawaii after posting beach photos on Instagram

"Authorities became aware of his social media posts from citizens who saw posts of him — on the beach with a surfboard, sunbathing, and walking around Waikiki at night," reads the release.
"

If you going to break the law, at least do not be stupid and advertise it. Oh, the arrogance.

 

[Sundog]

Less than 3 oz bottle of hand sanitizer
Glasses to protect eyes mucous membrane (not just normal glasses, but swimming type goggles type to wear on plane for "floating droplets/aerosols" like Ben wore)
Bandana, just in case and easy to pack

ETA: Reference to Ben is the first YouTube we followed here in thread #1/#2..... as he was in Wuhan when we first started following him. They knew that potential respiratory pathogen could get in through aerosols and in the air.. so he was ahead of the curve big time and never became positive)

On an airplane, perhaps for those who don't have goggles, and for those who are uncomfortable wearing the goggles, another option is to wear an eye mask that is designed for sleeping. Wear sunglasses and then change into eye mask for most of flight. Then throw away, or put in a zip lock bag to wash later.

 

[Sundog]

Midwest manufacturing workers sound alarm over COVID-19 outbreaks — NBC News

Not just meat packing facilities. Other manufacturing facilities with hundreds/thousands of people in close proximity on an assembly line, eating together in a common dining room or cafeteria, lined up to punch in and out, touching the same turnstiles, pulling down masks to be heard over the noise, touching same computers and controls....

Ford, Jeep and other assembly line workers are going back to work in Detroit and some Ohio cities next week. The companies have put in place some social distancing and other practices to keep workers safe, but that's another assembly line environment that is risky if things aren't done well.

 

[jjenny]

17 of the Oldest People in the World to Have Beaten COVID-19

New Jersey woman, 108, among world's oldest coronavirus survivors
For reference for those over 100.
There are several more.

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)31025-4/fulltext

Your lancet link says it's unlikely BCG vaccine given many years ago (in case of 108 year old woman, if she ever got it, it would have been over a 100 years ago) would have any effect on ameliorating covid now.

 

[Sundog]

Clinical trials are being done to figure out if something is promising (efficient) or not. Lots of clinical trials fail. So the idea that you only do clinical trials on something that will work doesn't hold water.

This is a misrepresentation of what I said. I said they are doing clinical trials because the drugs show some promise. The NIH doesn't pour money into clinical trials if they anticipate in advance that it is useless. Doesn't mean that the results will be positive, but it means that it is worth pursuing. These are very competitive research programs.

 

[jjenny]

This is a misrepresentation of what I said. I said they are doing clinical trials because the drugs show some promise. The NIH doesn't pour money into clinical trials if they anticipate in advance that it is useless. Doesn't mean that the results will be positive, but it means that it is worth pursuing. These are very competitive research programs.

As far as I can tell, so far most promise it showed is in killing people via cardiovascular side effects.

 

[tresir2012]

This vaccine doesn't even work that well against TB. It also doesn't work very well in adults against TB. How do they expect it to work against covid, especially considering most victims are older?
"BCG vaccination is rarely given to anyone over the age of 16 because it does not work very well in adults."
BCG tuberculosis (TB) vaccine overview

There are some who think it prepares immune systems to better deal with viruses.

"BCG vaccination can ready our immune system for viral infections. And a number of clinical trials have now begun to investigate whether a BCG shot given to those most at risk of contracting the infection can protect them from the disease.

Evidence that BCG protects against other infections
Benn’s work is among accumulating evidence, as detailed in a recent review paper, that childhood BCG vaccination protects against other diseases, so-called off target effects. Much of the evidence to support the new clinical studies is based on trials by her group and on work by Mihai Neteaof Radboud University Medical Centre in the Netherlands, who came up with a mechanistic explanation as to why BCG—designed to thwart a bacterial infection—could boost immune responses to viruses."

 

[firebird]

If you going to break the law, at least do not be stupid and advertise it. Oh, the arrogance.

Just for the record, these rules aren't laws. None of them were passed by the Legislature. Chances are, very few states would have them if the public had to vote imo

 

[tresir2012]

As far as I can tell, so far most promise it showed is in killing people via cardiovascular side effects.

Is there a link for that?

 

[jjenny]

There are some who think it prepares immune systems to better deal with viruses.

"BCG vaccination can ready our immune system for viral infections. And a number of clinical trials have now begun to investigate whether a BCG shot given to those most at risk of contracting the infection can protect them from the disease.

Evidence that BCG protects against other infections
Benn’s work is among accumulating evidence, as detailed in a recent review paper, that childhood BCG vaccination protects against other diseases, so-called off target effects. Much of the evidence to support the new clinical studies is based on trials by her group and on work by Mihai Neteaof Radboud University Medical Centre in the Netherlands, who came up with a mechanistic explanation as to why BCG—designed to thwart a bacterial infection—could boost immune responses to viruses."

I think there are easier and better ways to boost immune system.