I don't think information about this interesting study in front-line health care workers has been posted here. Recruiting is underway. BBM
Global trial to test whether MMR vaccine protects front-line health-care workers against COVID-19
Vaccine may strengthen immune response to viral infections; trial to enroll up to 30,000 health-care workers
Excerpts:
The research team leading the trial points to growing evidence that suggests the MMR vaccine may have benefits beyond protecting against measles, mumps and rubella. It could
broadly boost an individual’s immunity and may prevent infection from SARS-CoV-2 for a limited period. This is because the vaccine carries small amounts of live, weakened viruses that could train the body’s immune system to fight multiple pathogens.
(snip)
“We know that the MMR vaccine is safe, and we think there are
two main reasons that it could prevent COVID-19,” said one of the collaborative’s principal investigators,
Michael S. Avidan, MBBCh, the Dr. Seymour and Rose T. Brown Professor and head of the Department of Anesthesiology at Washington University. “
The first is this vaccine includes small amounts of live but very weakened measles, mumps and rubella viruses. This type of vaccine appears to strengthen the body’s immune response to infections in general, not just to the viruses in that particular vaccine.”
A second reason the MMR vaccine may be effective is that there are similarities between the weakened viruses in the vaccine and the SARS-CoV-2 virus that causes COVID-19. All of these viruses have similar proteins on their surfaces that are involved in infecting cells in the body, so the researchers think that antibodies made in response to the MMR vaccine also may recognize and fight the SARS-CoV-2 virus.
Unlike the drugs remdesivir and dexamethasone, the only medications so far identified as being helpful in treating COVID-19, the MMR vaccine would not be used to aid recovery from illness. Instead, the researchers want to learn whether the vaccine can elicit an immune response that slows the spread of the virus and protects front-line health-care workers who work in high-risk settings from developing COVID-19. The vaccine also will be examined to see whether it might reduce the severity of illness for those who do become infected.
(snip)
The study will recruit front-line health-care workers, including those from lower- and middle-income countries. The countries involved include Canada, Ghana, Ireland, South Africa, Uganda, United Kingdom, United States, Zambia and Zimbabwe.
(More at link.)
Information on the study at clinicaltrials.gov:
CROWN CORONATION: COVID-19 Research Outcomes Worldwide Network for CORONAvirus prevenTION - Full Text View - ClinicalTrials.gov