Coronavirus COVID-19 - Global Health Pandemic #81

[tresir2012]

I just want to reiterate that there are no FDA-approved treatments for Covid at this time.
COVID-19 Hub | Covid-19 Treatment Hub (this website is the COVID-19 Treatment Hub--Provides physicians, patients, and caregivers with information about the latest research in the fight against COVID-19)
(BBM a couple places in red below)

Navigating Medical & Treatment Developments for COVID-19
The COVID-19 Treatment Hub provides physicians, patients, and caregivers with information about the latest research in the fight against COVID-19. Many companies are currently developing new therapies and vaccines for coronavirus and/or evaluating how drugs that are currently available may treat the symptoms of COVID-19.

While there are no drugs, therapeutics, or vaccines yet approved to specifically treat, cure, or prevent COVID-19, there are options —from enrolling in clinical trials to requesting access to investigational products being tested by biopharmaceutical companies.

Clinical trials are necessary to gain regulatory approvals so new treatments are broadly available to patients as quickly as possible. Expanded access, which can provide access to investigational therapies when a patient does not qualify for a clinical trial, is sometimes available as well but must not interfere with clinical trials as it could delay availability of the approved treatment to the wider public. You can learn more about expanded access in our Expanded Access Navigator, which features guides for patients and caregivers, healthcare providers, and companies.

Use the links above to locate companies conducting COVID-19 research, learn about new and existing clinical trials, identify expanded access opportunities, and find trusted resources to guide you through this pandemic.

COVID-19 Evidence Accelerator
A collaboration of the Reagan-Udall Foundation for the FDA and Friends of Cancer Research, the Evidence Accelerator is an effort to accelerate the research community’s ability to coordinate the avalanche of real-world data being generated during this pandemic. The initiative will bring together members of the health data community to share insights and compare results through weekly data-sharing meetings. In addition, the Accelerator will gather a core group of health systems, academic, government, technology, and data organizations, each working in parallel to co-design and execute real-world studies to answer critical questions about the treatment and management of COVID-19.

Anti-Malaria & Other Anti-viral Drugs
Some approved medications are being studied to treat COVID-19 and are being made available under special circumstances. For example, on May 1, FDA issued an Emergency Use Authorization to allow remdesivir to be used for certain patients with severe COVID-19. In April, FDA issued a Drug Safety Communication cautioning against the use of hydroxychloroquine or chloroquine for COVID-19 outside of the hospital setting or a clinical trial due to risk of heart rhythm problems. You can find more information about hydroxychloroquine and remdesivir, including fact sheets for healthcare providers and patients, here.

Other antivirals are also being studied for efficacy in the treatment of COVID-19. Please visit our directory of companies investigating COVID-19 treatments for more information. Learn more about FDA’s efforts to facilitate development here.

Convalescent Plasma & Hyperimmune Globulin
One investigational treatment being explored for COVID-19 involves the use of convalescent plasma collected from recovered COVID-19 patients. It is possible convalescent plasma that contains antibodies to SARS-CoV-2 might be effective against the infection.

FDA issued an Emergency Use Authorization (EUA) for convalescent plasma on August 23, 2020. .... [snip] FDA is also helping to facilitate a collaborative effort with industry, academic, and government partners to implement a protocol for the use of convalescent plasma for patients in need across the country who may not have access to institutions with clinical trials in place. This does not include the use of COVID-19 convalescent plasma for the prevention of infection. Read FDA’s Guidance for Industry on Investigational COVID-19 Convalescent Plasma, and learn more here and here.

FDA is also working with industry and government partners to accelerate the development and availability of hyperimmune globulin for investigation for the potential treatment COVID-19. Hyperimmune globulin is a biological product manufactured from convalescent plasma. The FDA is helping to coordinate a study of hyperimmune globulin that will be conducted by the National Institute of Allergy and Infectious Diseases of the National Institutes of Health, as well as coordinating other efforts in this area.

[more at link]

Remdesivir is approved by the FDA but you are saying it isn't in your first paragraph. That's not correct.

 

[CSIDreamer]

Around here the non masker appear to be the majority just from what I have observed in person at gas stations, retail, convenience stores . More mask wearing at drug and grocery stores.
Mask wearers attempt to provide links to CDC information and state guidelines. Usually just a plea to wear masks when in public.
Non maskers lash out with remarks especially to older adults. Imagine a neighbor calling your mother a “mask-***”
on a neighborhood app.
JMO

Surprisingly, the majority (by and large ) of people I see out and about are masking up.

ETA do you have a mask mandate? We do but it isn't enforced.

 

[gitana1]

I just want to reiterate that there are no FDA-approved treatments for Covid at this time.
COVID-19 Hub | Covid-19 Treatment Hub (this website is the COVID-19 Treatment Hub--Provides physicians, patients, and caregivers with information about the latest research in the fight against COVID-19)
(BBM a couple places in red below)

Navigating Medical & Treatment Developments for COVID-19
The COVID-19 Treatment Hub provides physicians, patients, and caregivers with information about the latest research in the fight against COVID-19. Many companies are currently developing new therapies and vaccines for coronavirus and/or evaluating how drugs that are currently available may treat the symptoms of COVID-19.

While there are no drugs, therapeutics, or vaccines yet approved to specifically treat, cure, or prevent COVID-19, there are options —from enrolling in clinical trials to requesting access to investigational products being tested by biopharmaceutical companies.

Clinical trials are necessary to gain regulatory approvals so new treatments are broadly available to patients as quickly as possible. Expanded access, which can provide access to investigational therapies when a patient does not qualify for a clinical trial, is sometimes available as well but must not interfere with clinical trials as it could delay availability of the approved treatment to the wider public. You can learn more about expanded access in our Expanded Access Navigator, which features guides for patients and caregivers, healthcare providers, and companies.

Use the links above to locate companies conducting COVID-19 research, learn about new and existing clinical trials, identify expanded access opportunities, and find trusted resources to guide you through this pandemic.

COVID-19 Evidence Accelerator
A collaboration of the Reagan-Udall Foundation for the FDA and Friends of Cancer Research, the Evidence Accelerator is an effort to accelerate the research community’s ability to coordinate the avalanche of real-world data being generated during this pandemic. The initiative will bring together members of the health data community to share insights and compare results through weekly data-sharing meetings. In addition, the Accelerator will gather a core group of health systems, academic, government, technology, and data organizations, each working in parallel to co-design and execute real-world studies to answer critical questions about the treatment and management of COVID-19.

Anti-Malaria & Other Anti-viral Drugs
Some approved medications are being studied to treat COVID-19 and are being made available under special circumstances. For example, on May 1, FDA issued an Emergency Use Authorization to allow remdesivir to be used for certain patients with severe COVID-19. In April, FDA issued a Drug Safety Communication cautioning against the use of hydroxychloroquine or chloroquine for COVID-19 outside of the hospital setting or a clinical trial due to risk of heart rhythm problems. You can find more information about hydroxychloroquine and remdesivir, including fact sheets for healthcare providers and patients, here.

Other antivirals are also being studied for efficacy in the treatment of COVID-19. Please visit our directory of companies investigating COVID-19 treatments for more information. Learn more about FDA’s efforts to facilitate development here.

Convalescent Plasma & Hyperimmune Globulin
One investigational treatment being explored for COVID-19 involves the use of convalescent plasma collected from recovered COVID-19 patients. It is possible convalescent plasma that contains antibodies to SARS-CoV-2 might be effective against the infection.

FDA issued an Emergency Use Authorization (EUA) for convalescent plasma on August 23, 2020. .... [snip] FDA is also helping to facilitate a collaborative effort with industry, academic, and government partners to implement a protocol for the use of convalescent plasma for patients in need across the country who may not have access to institutions with clinical trials in place. This does not include the use of COVID-19 convalescent plasma for the prevention of infection. Read FDA’s Guidance for Industry on Investigational COVID-19 Convalescent Plasma, and learn more here and here.

FDA is also working with industry and government partners to accelerate the development and availability of hyperimmune globulin for investigation for the potential treatment COVID-19. Hyperimmune globulin is a biological product manufactured from convalescent plasma. The FDA is helping to coordinate a study of hyperimmune globulin that will be conducted by the National Institute of Allergy and Infectious Diseases of the National Institutes of Health, as well as coordinating other efforts in this area.

[more at link]

Whoa. So even if we had severe symptoms or money for private doctors, in the US, those treatments are only given for SOME of the gravely ill via a compassionate use waiver and/or clinical trial situations? So everyone else is basically left to get super sick and possibly die?

That makes the president’s outcome even more dangerous fodder for those downplaying this.

Ugh.

 

[Tadpole12]

Trump is on Twitter 1 min ago

 

[gitana1]

Remdesivir is approved by the FDA but you are saying it isn't in your first paragraph. That's not correct.

Whew. You’re right:

Today, as part of its ongoing efforts to fight COVID-19, the U.S. Food and Drug Administration broadened the scope of the existing emergency use authorization (EUA)for the drug Veklury (remdesivir) to include treatment of all hospitalized adult and pediatric patients with suspected or laboratory-confirmed COVID-19, irrespective of their severity of disease.

COVID-19 Update: FDA Broadens Emergency Use Authorization for Veklury (remdesivir) to Include All Hospitalized Patients for Treatment of COVID-19

 

[tresir2012]

That advice is only as good as the truthfulness of the patient.

Trump and Biden were double the recommended distance between them. That only works if both are not in the position to infect the other person. If the debate between Pence and Harris goes ahead they will be further apart but again, that only works if both parties are respectful of the others health.

That is all the doctor can go by though. If the patient says they have only seen their spouse for the last two weeks then that is what they will base their diagnosis on , unless they are obtaining their phone location data, which I doubt, or they are signed up to a CT app.

 

[Bravo]

I have been wearing a mask well before folks in my City were. Early to mid March IIRC. Then it became mandatory in hot spots. Now it's Province wide in Ontario.

 

[SouthAussie]

Whoa. So even if we had severe symptoms or money for private doctors, in the US, those treatments are only given for SOME of the gravely ill via a compassionate use waiver and/or clinical trial situations? So everyone else is basically left to get super sick and possibly die?

That makes the president’s outcome even more dangerous fodder for those downplaying this.

Ugh.

They need to develop an inexpensive Remdesivir in pill/capsule form.

Something that can be prescribed for the general infected population early on - non hospitalised people - and perhaps give everyone a fighting chance, and maybe lower the hospitalised numbers and costs.

IMO

 

[gitana1]

Sounds like Michael Moore.

Michael Moore floats conspiracy theory that Trump may be faking Covid diagnosis

Mr Moore said that Mr Trump may have the virus, but said the president lying about the virus had to be considered.

He went on to speculate as to why Mr Trump would fake having the virus after spending months downplaying its danger and publicly undermining guidelines meant to mitigate its spread.

Mr Moore believes the president is responding to polling data that suggests he is falling behind his campaign rival in the 2020 US election, Democrat Joe Biden. Under Mr Moore's theory, Mr Trump hopes to change the media narrative and garner sympathy amoung the public by pretending to have the virus.

Michael Moore claims Trump might be faking Covid diagnosis

Sounds illogical and to me. But it sounds downright delusional when it’s someone who supports and believes in the present. Does he feel someone is holding a gun to the president’s head and forcing him to pretend to have it? Does he believe the president is a hologram and he’s being held by the deep state?

The level of delusion and irrationality necessary for an actual supporter of the president to believe this could be a lie, is mind-boggling.

 

[LadyL]

If they can’t manage to keep themselves safe at a garden party, how are we supposed to feel confident that their pandemic response and policies can keep our nation safe?

Never mind. Rhetorical question.

EXACTLY.

 

[tresir2012]

Video and other messages from POTUS.

(Sorry I cannot get the video and other message to copy but click on the link below)

Donald J. Trump (@realDonaldTrump) on Twitter



Donald J. Trump

@realDonaldTrump

·

5h

OUR GREAT USA WANTS & NEEDS STIMULUS. WORK TOGETHER AND GET IT DONE. Thank you!

41.9K

73K

353.4K

 

[tresir2012]

They need to develop an inexpensive Remdesivir in pill/capsule form.

Something that can be prescribed for the general infected population early on - non hospitalised people - and perhaps give everyone a fighting chance, and maybe lower the hospitalised numbers and costs.

IMO

I don't think it as simple as that when it is about the immune system. If it was easy they would have cured HIV by now IMO.

 

[ilovewings]

Sounds illogical and to me. But it sounds downright delusional when it’s someone who supports and believes in the present. Does he feel someone is holding a gun to the president’s head and forcing him to pretend to have it? Does he believe the president is a hologram and he’s being held by the deep state?

The level of delusion and irrationality necessary for an actual supporter of the president to believe this could be a lie, is mind-boggling.

Michael Moore sounds ridiculous-- he is going to lose any credibility he ever
had

 

[SouthAussie]

I don't think it as simple as that when it is about the immune system. If it was easy they would have cured HIV by now IMO.

I am not speaking of a cure. I am speaking of a treatment. A non-hospitalisation-required treatment.
There are good treatments for HIV now, which is why the HIV deaths are now minimised.

IMO

 

[tresir2012]

If they can’t manage to keep themselves safe at a garden party, how are we supposed to feel confident that their pandemic response and policies can keep our nation safe?

Never mind. Rhetorical question.

If we cannot keep our elderly in care homes safe, or our leaders and government safe, then nobody is safe.

 

[cass523]

What Presidents Do and Don’t Say About Their Health

Americans are naturally curious about the health of their president, and any sign of illness or frailty gets subjected to intense public scrutiny. That was not always the case. The U.S. presidency has a checkered history with truth and disclosure when it comes to infirmity and maladies, especially with potentially serious situations such as President Donald Trump contracting Covid-19.

1. How much must presidents disclose about medical conditions?

There are no legal requirements imposed on the president to inform the public about his or her health. Modern-day presidents have traditionally been quite open with details, however. Barack Obama released full details of his health checks, including one in March 2016, shortly before he was due to leave office. George W. Bush also shared detailed medical reports.

2. What do we know about Trump’s general health?

Trump, who turned 74 in June and was the oldest U.S. president to be sworn in for a first term, is not quite as forthcoming with details about his health. The most recent report from his doctor, released in June, said Trump “remains healthy,” also remains obese as measured by his body-mass index, and had reduced his total cholesterol level to 167, within the normal range, by taking 40 milligrams daily of the statin rosuvastatin, more widely known under the brand name Crestor. But an unannounced, and still mostly unexplained, visit to a Washington-area hospital in November 2019 still prompts speculation that he had a health problem. Trump, perhaps inadvertently, fueled that speculation with a Sept. 1 tweet denying “having suffered a series of mini-strokes.”

What Presidents Do and Don’t Say About Their Health

Donald J. Trump@realDonaldTrump 34m

video

https://twitter.com/realDonaldTrump

 

[tresir2012]

I am not speaking of a cure. I am speaking of a treatment. A non-hospitalisation-required treatment.
There are good treatments for HIV now, which is why the HIV deaths are now minimised.

IMO

They have several treatments as well as Remdesivir including dexamethasone, interferon B, convalescent plasma etc but it is all still in clinical trials being assessed. They can't develop it unless they know it works and has no side effects.

 

[Medstudies]

Well my government says 2 metres so that is the rule we follow.

Staying safe and social distancing | GOV.WALES

I get it, but hey, I was just providing an answer to your question on where the numbers came from.

 

[cass523]

6 pm The president's doctor, Sean Conley, caused some confusion when discussing Donald Trump's condition on Saturday.

4:06

To view this content we will need your consent to set third party cookies.
For more detailed information, see our cookies page.

Accept third party cookies

 

[branmuffin]

That is all the doctor can go by though. If the patient says they have only seen their spouse for the last two weeks then that is what they will base their diagnosis on , unless they are obtaining their phone location data, which I doubt, or they are signed up to a CT app.

A patient who lies or doesn't provide the proper information to the doctor is guilty of endangering everyone they come in contact with. Doesn't matter if the subject is Covid, AIDS or TB. People lie because they are lazy.

But as far as I'm concerned advice from your doctor will never trump civic responsibility. Civic responsibility is a two way street: for everyone who willingly wears a mask, reduces their interaction with the general public, maintains safe distances to avoid infection there are individuals who believe that personal freedom outweighs the threat they pose.

It's not unusual for the general public to hold these people up for ridicule or worse. Public stocks, shaving the heads of Nazi collaborators, and even worse have been enacted when individuals weighed their own interests against the greater good.