Coronavirus COVID-19 - Global Health Pandemic #88

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  • #521
IMO because 380 million is a very, very, very large number. And it's possible people will need more than 1 jab.

Maybe a factory can quickly produce 380 million paper clips, but 380 million (or potentionally 760 million) doses of a highly sensitive biomedical product that must be manufactured to extremely rigorous standards and subject to very high quality control (oops, that batch of 5000 doses was substandard, oh well, mistakes happen).

Then it needs to be administered. How many people are there to administer this vaccine? You can't just diy or just hire college kids. Lets say, 20,000 nurses can be recruited to just do that. That means each nurse has to do 17,500 doses. Can you imagine administering 17,500 shots? How many per day can one person do? I have no idea. But I don't think each person could do 500 per day, which would get it done in a month.

By the time that happens we may all be waiting in line to receive our vaccines - along with waiting in line for bread, meat, and chocolate.
 
  • #522
Breaking
New York City public schools will begin reopening in-person learning in early December, mayor says
More at link
New York City public schools grades 3-k, Pre-k, and K-5th grade will begin reopening for in-person learning Dec. 7, Mayor Bill de Blasio said.

Schools will begin reopening in phases, de Blasio said.

Students will be tested weekly and parents will be required to sign a consent form for every student that will take in-person classes, de Blasio said.

“It’s less concern about the spread when it comes to younger kids,” de Blasio said.
Nearly 300,000 students are eligible to return to school, according to de Blasio.

District 75 schools, which provide specialized instruction for students with significant needs, will reopen beginning Dec. 10, de Blasio said

Schools are moving to five-days a week of in-person classes as much as possible, the mayor said.



*blink blink blink*
I want all kids back to school soooo bad
But the timing feels all wrong idk
(But I’m not a scientist ...so maybe this will all be just fine)
Lookin at you MA and CO too
 
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  • #523
Why do you think it would take 6-7+ months to distribute a vaccine once approved? That seems unreasonable to me. We know a vaccine is coming. Preparation is underway to manufacture and distribute it. Once we have a new leadership in place, expectations are high that they’ll be efficient and effective. To me, months and months to get a basic shot out to the public isn’t reasonable.
—-
Because I would like to be optimistic but I have been disappointed on how things in the US and the state has been handled - it’s just my opinion.

Let’s say - 55 years old with no underlying major health issues or immune compromised. Blood pressure and other vitals are good. Need to lose the Covid-15.
Older adults are those over 60? Possibly 55?


U.S. advisory group lays out proposal on how to prioritize Covid-19 vaccine

“The resulting recommendations put health workers in high risk settings and first responders to the very front of the vaccination line, in what the committee called the “jumpstart phase.” Closely behind are adults of any age who have medical conditions that put them at significantly higher risk of having severe disease, primarily heart or kidney failure or a body mass index of 40 and over. Also in this group are older adults living in long-term care homes or other crowded settings.

The report suggests that a second phase of vaccinations should involve critical risk workers — people in industries essential to the functioning of society — as well as teachers and school staff; people of all ages with an underlying health problem that moderately increases the risk of severe Covid-19; all older adults not vaccinated in the first phase; people in homeless shelters and group homes, and prisons; and staff working in these facilities.

Young adults, children, and workers in essential industries not vaccinated previously would make up the third priority group. Remaining Americans who were not vaccinated in the first three groups would be offered vaccine during a fourth and final phase.”
 
  • #524
Ran out of time on above post, continued below:
Qmfr:
From the above JAMA link dated Nov. 23:

“In addition to respiratory illness, concerns have arisen around multisystem inflammatory syndrome in children (MIS-C).13 An Italian series of 10 cases of Kawasaki-like syndrome included 8 patients with antibodies against SARS-CoV-2.14 New York state has reported more than 100 cases of Kawasaki-like disease, including 3 deaths, among children with COVID-19.15 Our evolving knowledge of MIS-C suggests that available evidence may be revealing only a partial picture of the effect of COVID-19 in the pediatric population.“

Exactly what I alluded to above, jmo.

All one needs to do is visit the link here and see that by no mean are kids out of the woods with this. As for rare, what does one consider rare? A hundred kids? A thousand kids? Ten thousand kids? These numbers are increasing. We need to start protecting the children, jmo, even if many may escaped unscathed. We do not know the long term effects fully. And it is evident that some children ARE experiencing them.

Some quick recent examples / See childrens’ stories and some of their effects / one must realize that these are only some of the cases that we are hearing about:

MIS-C in Atlanta child who had COVID-19 | wtsp.com

Mattapoisett boy battles COVID-19 and MIS-C
Nov. 25, 2020

“Dr. Brian Sard, the chair of pediatrics and director of the Boston Children's Hospital program at St. Luke's, said that MIS-C can present itself after acute COVID-19 exposure has passed. In Cooney's case, MIS-C symptoms of fever and rash followed his mild cold symptoms. Sard said that MIS-C can present itself in a constellation of symptoms similar to those in Kawasaki disease such as red eyes, swollen glands, rash, mucositis, swelling of hands or feet and GI problems.

Xifaras, herself a nurse, said a slew of new symptoms appeared over the next few days.

"It's unnerving because this isn't like an ear infection or strep throat where you know what's next," she said. "Every day there is something new."

de07fda9-3d40-4634-a88a-0d5001a106de-Cooney_Family2.jpg


BBM:
According to Dr. Reynolds, Cooney's fever improved but then spiked again and he developed a severe pain in his left hip. The doctors were worried about toxic synovitis, where the soft tissue of a joint becomes inflamed. Cooney was admitted to Boston Children's Hospital to be further treated. Upon being admitted, he tested negative for COVID-19. As of Monday, it was confirmed by rheumatology that he had a mild case of MIS-C but there is still concern for the residual cardiac effect.


YOUNG BOY ON THE UP AND UP FOLLOWING SERIOUS HEALTH SCARE - Florida Keys Weekly Newspapers
Nov. 25, 2020



“Before Zane was admitted, no symptoms of COVID-19 were apparent. Three tests performed came back negative. It wasn’t until a 105-degree fever that Leah knew something was seriously wrong.

A positive antibodies test, however, led doctors to the belief that Zane had multisystem inflammatory syndrome, or MIS-C. While some eventually improve with medial care, others get worse — as was the case for Zane. With dips in his condition, from swelling to rash, came improvements, to the point of his release from the hospital on Aug. 4.

Today, Zane’s parents say his health is improving with his organs shrinking and returning to normal. Doctors continue to closely monitor an enlarged left lung artery and a heart murmur he developed through the illness, however.

[...]

“Zane has faced several life-threatening issues in his young life, as Dr. Stan Zuba said MIS-C attacked the young boy’s body so aggressively that there were times he didn’t know if he was going to pull through. But he did, Zuba says, with outstanding and state-of-the-art care and treatment at Nicklaus Children’s Hospital.“
—-

MIS-C in Atlanta child who had COVID-19 | wtsp.com
Nov. 25, 2020

“The Vasey Family thought they had beaten COVID-19.

It had been a few weeks and they were all feeling great but then Vivian started to get sick again, and they couldn't figure out what was wrong.

"I walk in to her room, and she's in a ball on the floor. And she's like, 'Mommy, my legs don't work. I can't walk,'" said Miranda Vasey.”

[...]

“"MIS-C, we only have data that goes back 10 months. From my understanding, we have only had 15,000 cases. So we don't know what the long-term effects of this will be on our child," she said.

In Georgia, there have been 83 confirmed cases of the disease according to the health department. Nationwide, there have been 20 pediatric deaths.

While the CDC classifies MIS-C as rare, the doctors treating Vivian told her family they're seeing a kid a week show up with symptoms.

"Parents need to know that kids can get really sick. You can't trust people to do the right thing, and if your child gets COVID-19, you need to have MIS-C on your radar, and you need to know that between two to four weeks later your child can get really sick," she said.”

-

MIS-C: What to know about the COVID-19 related illness seen in kids
Nov. 16, 2020

“Twelve-year-old Madilyn Dayton's symptoms began with a headache and body aches.

Two to three days later, she couldn't walk or eat, and rashes appeared all over her body.

Then, she couldn't move at all.

"I remember my mom driving me to the hospital... and then I woke up in the ICU the next morning," she said.“
--

Hudson Asche returns home to recover from MIS-C
Nov. 10, 2020

5fa974511b10d.image.png

Hudson

“On Hudson's caringbridge.org page, his mother Dana said he arrived back home last Sunday night, and he is still feeling "very sick and the doctors explained he is not going to just bounce back but it will take weeks to start feeling better, and close to 6 months before he feels back to normal." Dana said COVID and MIS-C have weakened Hudson and he will be going to physical therapy 2 to 3 times a week.“


Pediatricians call number of children with COVID "staggering and tragic" - WISH-TV | Indianapolis News | Indiana Weather | Indiana Traffic


Southern Indiana boy, 6, hospitalized with rare COVID-related syndrome MIS-C

Long Recovery Ahead For Minn. Teen Who Contracted Rare COVID-Related Syndrome MIS-C

Teen facing long recovery after suffering rare COVID-related syndrome

Little boy who died in Lubbock hospital after MIS-C was 3rd grader from Odessa

WATCH: Covenant Children’s hosts news conference to discuss a rise in cases of MIS-C in West Texas

Research Roundup: COVID; MIS-C; Leukemia; Childhood Cancer

Multi-system inflammatory syndrome, how's related to coronavirus | abc10.com
'My son almost died.' Mom issues warning after son is diagnosed with MIS-C which is connected to COVID-19
A pediatrician at Norton Children's Hospital said they've treated about a dozen children with multi-symptom inflammatory syndrome (MIS-C).


W. MI child’s death linked to COVID-19 | WOODTV.com
Nov. 21, 2020

GRAND RAPIDS, Mich. (WOOD) — A West Michigan child has died from complications thought to be directly related to coronavirus.”

[...]

“Unfortunately, we’ve been seeing cases of MIS-C at Helen DeVos Children’s Hospital. It’s a byproduct of coronavirus that we’re not totally sure of the whole connection,” said Dr. Daniel McGee, pediatric hospitalist.

The hospital says it couldn’t give specifics about the child’s age or when the child died.

However, officials say several children have been admitted to the hospital with MIS-C over the last few months.

“We’ve had at least a few patients hospitalized because of it. In the last week, there were at least two,” he said.““


Florida:

“There were 5,970 pediatric coronavirus cases Monday, compared to 1,657 on October 5

Data shows a rapid increase in pediatric COVID-19 cases since early October”


Experts Concerned About Florida Spike in Child COVID-19 Cases


Nov. 24
Over 1,000 Children Have Developed Multisystem Inflammatory Syndrome After Contracting COVID

Nov. 19
6-year-old diagnosed with MIS-C released from hospital

Nov. 17
COVID, MIS-C show evidence of liver injury, require long-term monitoring

Higher SARS-CoV-2 antibody titers in patients hospitalized with MIS-C | 2 Minute Medicine

Nov. 16
A serious illness related to COVID-19 is showing up in Utah kids. Here's what you need to know
MIS-C: What to know about the COVID-19 related illness seen in kids

Nov. 15
Norfolk hospital has treated 7 children for rare coronavirus-linked syndrome


“Since the start of the COVID-19 pandemic, more than 1 million infants, children and adolescents have been diagnosed with the illness, according to data released Monday by the American Academy of Pediatrics and Children’s Hospital Association, which are tracking data reported by state health departments.

As of Nov. 12, a total of 1,039,464 children have tested positive for COVID-19 since the onset of the pandemic. In the one-week period ending Nov. 12th, there were 111,946 new cases in children, which is substantially larger than any previous week in the pandemic. The increase tracks surges in the virus in communities across the U.S.

“As a pediatrician who has practiced medicine for over three decades, I find this number staggering and tragic. We haven’t seen a virus flash through our communities in this way since before we had vaccines for measles and polio,” said AAP President Sally Goza, MD, FAAP. “And while we wait for a vaccine to be tested and licensed to protect children from the virus that causes COVID-19, we must do more now to protect everyone in our communities. This is even more important as we approach winter, when people will naturally spend more time indoors where it is easier for the virus to be transmitted.”

More Than 1 Million Children in U.S. Diagnosed with COVID-19


“While some cases of the coronavirus tend to be mild for children, more than 1,000 children have developed multisystem inflammatory syndrome in children (MIS-C). It’s a rare but serious complication that can occur after COVID-19 infection.

Four-year-old K.J. Griffin is the first child in the country to receive an experimental treatment for MIS-C. His mom, Talaiyah Stephens, cannot believe she came so close to losing him.”

[...]

“Dr. Allison Eckard, division director of pediatric infectious diseases at Medical University of South Carolina says, “His body was no longer pumping blood effectively to his vital organs, and they were starting to shut down.”

K.J. received high dose steroids, and aspirin, and plasma, as well as other drugs to help prevent blood clots. Doctors determined he was also a candidate for an experimental treatment called Remestemcel-L, which uses donor bone marrow cells to regulate the immune system.

“It acts as if that person is making those cells themselves, and so they circulate in the blood and release anti-inflammatory cytokines,” Dr. Eckard says. “The thought is that not only does it turn down inflammation, but it actually repairs some of the damage that’s been done.”“

Over 1,000 Children Have Developed Multisystem Inflammatory Syndrome After Contracting COVID
Nov. 24, 2020


Boy under age of 10 becomes Manitoba's youngest COVID-19 victim, 487 new cases reported
Nov. 28, 2020

“An additional 10 deaths due to COVID-19 were announced Saturday by public health officials including a boy under the age of 10 from Winnipeg, the youngest Manitoba victim since the pandemic began.“


Experts Concerned About Florida Spike in Child COVID-19 Cases

“It’s estimated at the least that more than 1 million children (under the age of 18) in the U.S. are, or have been, infected with COVID-19.

While kids are often reported to have less severe symptoms, Wheeler said that should not give blanket comfort.

“The concern though is there is still a subset of children who go on to develop more severe symptoms and symptoms that require hospitalization,” Wheeler said
.

Kids are often believed to transmit COVID-19 at a lesser rate than adults, but Wheeler said it is a risk that remains concerning.

Youth will also be a focal point as pharmaceutical companies get closer to releasing a COVID-19 vaccine.

We need to make sure we’re paying attention to our pediatric population,” Wheeler said. “We have so much focus on adults getting sick and we need to remember that kids are impacted too. Kids aren’t little adults, kids need their own research, their own data, and we need to be cautious.

"While kids are doing well in general with COVID, there are still some getting really sick and we need to be doing everything we can to protect not only our adult population, but to be protecting our kids as well.”“

BBM

COVID-19 and MIS-C: Two Diseases, One Virus in Kids
— Both clinical profiles and even outcomes varied, researcher says

Nov. 17, 2020

“Pediatric patients with acute COVID-19 and those with multi-system inflammatory syndrome in children (MIS-C) had evidence of acute liver injury, but each group had different clinical features, a researcher said.

MIS-C patients were younger, had more ICU admissions, and higher levels of inflammatory markers, while COVID-19 patients with acute liver injury were more likely to have higher BMI
, reported Amanda Cantor, MD, of Columbia University in New York City.

In fact, BMI was significantly associated with degree of liver injury among kids with COVID-19, but not MIS-C, she said in a presentation at theAmerican Association for the Study of Liver Diseases virtual meeting.

Cantor described how there were "two distinct clinical phenotypes caused by the same virus." She and her colleagues added that MIS-C "changed the perception of the severity of this infection in children," as pediatric manifestations of COVID-19 in children were thought to be mild.“


Now, keep in mind, this is just one hospital, and as seen in the above quoted post, this is not the only hospital to say they are seeing more and more patients:

“While the CDC classifies MIS-C as rare, the doctors treating Vivian told her family they're seeing a kid a week show up with symptoms.“

MIS-C in Atlanta child who had COVID-19 | wtsp.com


News 8: What’s it like treating these patients?
McGee: I’d rather not have to do it. These are children that can get very, very sick and as I’ve said before some of these kids can die. This virus is real. This virus is dangerous. It doesn’t matter whether you’re a child or an adult. So, we all have to be careful to make sure we don’t get it because your child could be the one that suffers from a major consequence.“


Re: Here is another reason why I think it’s possible we are not seeing the full spectrum here:

“Nelson Delacruz, an epidemiologist for the state, confirmed the hospital’s cases had been reported. But while public health investigators counted them toward Virginia’s COVID-19 cases, they did not for MIS-C.

That’s because the department did not consider them to meet the U.S. Centers for Disease Control and Prevention’s narrow definition for the syndrome.
Delacruz could not elaborate on how the cases differed.“



CDC:

“Clinical Presentation
Patients with MIS-C usually present with persistent fever, abdominal pain, vomiting, diarrhea, skin rash, mucocutaneous lesions and, in severe cases, with hypotension and shock. They have elevated laboratory markers of inflammation (e.g., CRP, ferritin), and in a majority of patients laboratory markers of damage to the heart (e.g., troponin; B-type natriuretic peptide (BNP) or proBNP). Some patients develop myocarditis, cardiac dysfunction, and acute kidney injury. Not all children will have the same signs and symptoms, and some children may have symptoms not listed here. MIS-C may begin weeks after a child is infected with SARS-CoV-2. The child may have been infected from an asymptomatic contact and, in some cases, the child and their caregivers may not even know they had been infected.”

Multisystem Inflammatory Syndrome in Children (MIS-C)



ETA: My final assessment after posts above indicate that IMO, as a result of MASSIVE family travel and gatherings over Thanksgiving, as well as an already severely escalated Covid situation, there is very likely IMO going to be a surge of children, and babies, who will get very ill, have potential long term effects, and some (more) will die. Again, this is not something we are seeing a lot of talk about (yet), but wait for it, imo. This is very upsetting, especially considering much will occur due to disinformation and outright disregard, which could have been prevented.

Yesterday I mentioned the guilt that some may later feel for infecting their family members as a result of Thanksgiving travel - well, I now revise this to include guilt over their children who, as seen above, could become sick and die as a result - “rare” or not. Again, what does one consider “rare” - there comes a point where even a small percentage results in a large number when there is this much community spread. IMO, with increasing cases, this will become “not as rare” as previously described, simply due to increased spread/prevalence, jmo.
 
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  • #525
Discussion today re infections and infectious doses

According to this, CDC has estimated that 16% of the US population (53,000,000) has already been infected. 14:25 on the video
 
  • #526
There are now (November 27) in my region 1,952 confirmed cases of Covid-19, an addition with 53 cases from the day before; 9 hospitalized, 1 in intensive care; and there have been 23 deaths. I worked night on Thursday, and there were several patients admitted that had Covid-19, either confirmed, or suspected, tested, and placed in isolation care until the tests are analysed.
Senaste nytt om coronaviruset i Blekinge

On November 27 there were 14 new cases of Covid-19 among staff and/or family that work at mink farms in my region, five more than rwo days ago. There are several mink farms in Sölvesborg, close to the border to Scania.
14 nya covidfall utreds – koppling till minkfarmar
 
  • #527
It must also be noted FTR, as I’ve run out of time again on post, that there are also documented cases of post-Covid inflammatory syndromes appearing in adults, similar to MIS-C.



Eta: Yeah, I’m pretty upset about my friend exposing all his kids. Why even chance it so carelessly and unnecessarily.

There are so many health workers sleeping in their basements and cars so they don’t expose their families. I’ve heard health worker after health worker on YT (the majority of which are usually crying) say that their biggest fear is bringing it home to their children.

More people are going to learn a very hard truth after Thanksgiving, IMO. Sadly some of their children, (or someone’s else’s children), whether it’s one, one hundred, one thousand, will pay this price. There have already been over a thousand known cases of MIS-C, but as indicated above, these numbers could be underestimated, imo.

IANAD.
 
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  • #528
IMO because 380 million is a very, very, very large number. And it's possible people will need more than 1 jab.

Maybe a factory can quickly produce 380 million paper clips, but 380 million (or potentionally 760 million) doses of a highly sensitive biomedical product that must be manufactured to extremely rigorous standards and subject to very high quality control (oops, that batch of 5000 doses was substandard, oh well, mistakes happen).

Then it needs to be administered. How many people are there to administer this vaccine? You can't just diy or just hire college kids. Lets say, 20,000 nurses can be recruited to just do that. That means each nurse has to do 17,500 doses. Can you imagine administering 17,500 shots? How many per day can one person do? I have no idea. But I don't think each person could do 500 per day, which would get it done in a month.

And let's not forget the issues with vaccine transportation, storage, and retention. Subzero for one vaccine, very cold for the other.

The NBC News report that @margarita25 posted yesterday featured a doctor from Cedars-Sinai hospital. The reason they were speaking with him is because Cedars-Sinai hospital is one place that has subzero storage for a defined (not unlimited) amount of storage. There are not too many places that have this kind of storage.


Cedars-Sinai was selected as one of the distribution sites because of its ability to store vaccines at ultra-cold temperatures. The freezers can keep medicines as cold as -80 degrees Celsius.
“As a major research center, we need that ultra-cold storage to support some of our research projects. So we already had them on site and available,” said Dr. Jeff Smith, the hospital’s chief operating officer.
Cedars-Sinai hospital freezers are being prepped for coronavirus vaccine storage | KTLA
 
  • #529
I’m not really following the vaccine stuff in detail. Other than seeing it as a pinpoint of light at the end of the tunnel

It suuuuuure would be nice to get some of these kids (and teachers) jabbed and back in school ASAP (After hc and other essentials of course)Maybe during the same phase as over the 60s? Let’s prioritize the kids and old folks for once this pandemic huh?

I think many more than the usual number of vaccine decliners will pass (including hc&essential workers and parents of school aged kids) so that will hopefully move the timeline slightly ahead a smidge for everyone else.

Imma guessing April/may *to start for the general population


Eta links
975 Doses Per Delivery, And Other Coronavirus Vaccine Details For Massachusetts Hospitals

Far More Doses of COVID Vaccine Than Expected May Be Available in Mass. By Year-End

I think young kids will be way down the list. I read yesterday that only one vaccine has been tested on any children, and those were 12 years old and above.

The article I read was saying how kids need to be involved in the vaccine testing. I kind of shuddered (even though I realise that kids need to be vaccinated) because I wondered who was going to put their young children up for experimentation.

They mentioned that once we felt confident that adults were responding well, they would start (testing) lower doses on children. See what kind of dose they need. Presumably they wont need (and maybe can't handle) an 'adult strength' dose.
 
  • #530
I think young kids will be way down the list. I read yesterday that only one vaccine has been tested on any children, and those were 12 years old and above.

The article I read was saying how kids need to be involved in the vaccine testing. I kind of shuddered (even though I realise that kids need to be vaccinated) because I wondered who was going to put their young children up for experimentation.

They mentioned that once we felt confident that adults were responding well, they would start (testing) lower doses on children. See what kind of dose they need. Presumably they wont need (and maybe can't handle) an 'adult strength' dose.

My husband is on board to get a vaccine. I wonder how long it will take though? He is in one of the highest risk categories.

I think that the news about a vaccine is great. But if it takes 12 to 18 months to roll out to even priority people, that is still a long ways away.
 
  • #531
Bumping as someone was talking about ages... This previous post has the info
Moderna - Tested on 18 years and up
Pfizer - Tested on 12 years and up
Oxford/AstraZeneca - Tested on 5-12 and 18 years and up

Bringing this information forward on costs/ages/quantities from my earlier posts due to Oxford/AstraZeneca coming out... just as a refresher on who pre-ordered what, and costs. Also of note, adding ages that were in the trials from earlier post. Also added Operation Warp Speed document which gives more information.

Roll outs
Moderna/NIH
20 million doses ready by end of 2020; 500 million to one billion doses in 2021. Can be manufactured in US, Switzerland and Spain. Advanced orders are US order was for 100 million doses with options on 400 million more; EU 80 million doses; Japan 50 million doses; Canada 20 million; Switzerland 4.5 million; UK 5 million doses for spring. They are in talks with WHO, COVAX re distribution and a tiered pricing proposal.
Cost expected $32-37/dose Tested on 18 Years old and up

Pfizer 50 million doses by end of 2020. Advanced orders are US 100-500 million; EU 200 million; UK 40 million doses
Cost expected $19.50/dose Tested on 12 years old and up

AstraZeneca/Oxford
EU 400 million doses; UK 100 million doses; alliance for poorer countries 300 million doses. ETA below 300 million for US
Cost expected $5/dose Tested on 5-12 years old and 18 and up

Sanofi and GlaxoSmithKline
No info on.
Cost expected $12/dose

Source:

Coronavirus COVID-19 - Global Health Pandemic #87

Coronavirus COVID-19 - Global Health Pandemic #87

I had never read this before... information on operation Warp Speed which I found of interest much of the info.
Fact Sheet: Explaining Operation Warp Speed

Inserting ETA on 11/29 from SouthAussie to keep this information up to date U.S. gives AstraZeneca $1.2 billion to fund Oxford University coronavirus vaccine — America would get 300 million doses beginning in October

ETA @SouthAussie
 
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  • #532
Jumping off this discussion, another thing wrt the vaccine, which we’ve seen discussed by Dr. Fauci, Dr. Gupta, etc., and have also touched on here, is that the “vaccine“ can only do it’s job through the process of “vaccination“, so approaching the whole “vaccine trust” and convincing people to take it is also a challenge.



Let’s keep the numbers easy for the sake of simplicity and clarity at 50/50. Let’s say half of the general population (non prioritized) will choose to get vaccinated, and half won’t, then what does that look like...

Would you guys say that’s a fair baseline to start with? Would any of you venture to guess if you think more people WILL take the vaccine vs. NOT take the vaccine, or vice versa?


Another thing, IIRC, Dr. Swaminathan said that 6 months is recommended/required for Stage 3 Trials (wrt COVAX). I do recall some of those beginning in June, so that would be on point for some (need to refresh which ones).

However, maybe I dreamed this, but I could’ve sworn I read/saw something the other night re: some of the US’ latest vaccines - that it/they had a reduced phase 3 time of only 2 months, note to check USA FDA JS EUA vaccination notes. Jmo, moo, not sure about this.



Pfizer and BioNTech Conclude Phase 3 Study of COVID-19 Vaccine Candidate, Meeting All Primary Efficacy Endpoints | Pfizer
November 18, 2020
 
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  • #533
Bumping as someone was talking about ages... This previous post has the info
Moderna - Tested on 18 years and up
Pfizer - Tested on 12 years and up
Oxford/AstraZeneca - Tested on 5-12 and 18 years and up



ETA @SouthAussie

Thanks, Dixie. I guess the article I read (about young kids) was about Pfizer and Moderna vaccines that will be available in the US.
Has the US bought in to the Oxford Astra Zeneca vaccine?

ETA: Yes it has.
U.S. gives AstraZeneca $1.2 billion to fund Oxford University coronavirus vaccine — America would get 300 million doses beginning in October
 
  • #534
Jumping off this discussion, another thing wrt the vaccine, which we’ve seen discussed by Dr. Fauci, Dr. Gupta, etc., and have also touched on here, is that the “vaccine“ can only do it’s job through the process of “vaccination“, so approaching the whole “vaccine trust” and convincing people to take it is also a challenge.



Let’s keep the numbers easy for the sake of simplicity and clarity at 50/50. Let’s say half of the general population (non prioritized) will choose to get vaccinated, and half won’t, then what does that look like...

Would you guys say that’s a fair baseline to start with? Would any of you venture to guess if you think more people WILL take the vaccine vs. NOT take the vaccine, or vice versa?


Another thing, IIRC, Dr. Swaminathan said that 6 months is recommended/required for Stage 3 Trials (wrt COVAX). I do recall some of those beginning in June, so that would be on point for some (need to refresh which ones).

However, maybe I dreamed this, but I could’ve sworn I read/saw something the other night re: latest vaccines - that it/they had a reduced phase 3, only 2 months, note to check US FDA JS EUA vaccination notes.

An Aussie friend of mine has been taking a little Yes/No survey on FB.

So far:

22 say yes they will have the vaccine right away
4 say no
5 say they will wait for a while, see how it goes
 
  • #535
  • #536
Nooooooo...

Canada....what happened...you guys were doing so well, and have really had it together...

Seriously, I’m interested in what the heck happened....It’s been so crazy here in the States, and I haven’t kept up with Canada, but have been meaning to, as you know I was very interested and still am interested in other countries as well, and was watching Global News Canada daily in the early days and posting videos...

Gosh, I hope you guys can put out the fires.

Keep caring, keep fighting
(waving Canadian flag)

@LadyL , pls keep us updated on the Ontario “nosocomial situation”...



Yeah, I’m not liking these numbers out of Manitoba...sounds all too familiar...

“The current five-day COVID-19 test positivity rate is 14.2% provincially and 13.9% in Winnipeg, both down from Friday’s numbers. As of 9:30 a.m., Saturday, 487 new cases of the virus have been identified and the total number of lab-confirmed cases in Manitoba to 16,118. The vast majority of the new cases – 307 – come from Winnipeg while there were 104 new cases in Southern Health, 38 in Northern, 23 in Interlake-Eastern and 15 in Prairie Mountain Health region.

There are currently 9,024 active cases including 6,537 from Winnipeg while 6,804 individuals have recovered from COVID-19. There are a pandemic-high 327 people in hospital with 44 people in intensive care.“

I'm so worried. I don't feel like we have it under control. At all.
 
  • #537
BC. Canada. Yes, our numbers are spiking. Scary times. I think it’s the result of all of it. Canadian Thanksgiving. Halloween just prior to that. Kids back to school and college. Covid fatigue. Covid denyers, Mask debaters and the onset of winter. With talk of a vaccine I think people began believing it was almost all over, despite that they have been warning us all along that this virus likes the cold...and we are now basically into winter temperatures in many areas of the country. We are on restrictions to have no one in our homes but those who live in the home and to avoid all travel except for necessities. No groups..indoors or outside and masks must now be worn in all public buildings and so on. This is until Dec 7, but I will not be surprised to see it extended. I have an aunt, age 82 in quarantine as her 83 year old husband has
Covid. They have no idea where he got it as they only leave their home for groceries and do wear masks, use sanitizer, wash their groceries and spray their mail. Apart from having lost a lot of weight, he seems to be recovering well and so far she has no symptoms. My other remaining aunt ( both are my deceased mothers sisters) is age 100 and in a care home which is now riddled with Covid. I don’t have much hope she will survive this. It’s all very depressing as you well know.
On another note I have been thinking a lot about Kali, and hoping she’s okay as I don’t think she’s checked in for a while.

I'm sorry about your aunts and uncle. It's so scary when our elderly have to endure this.
 
  • #538
Per last night’s NBC News, iirc, the numbers re: latest nursing home outbreaks were discouraging. Noting to follow up.
 
  • #539
Jumping off this discussion, another thing wrt the vaccine, which we’ve seen discussed by Dr. Fauci, Dr. Gupta, etc., and have also touched on here, is that the “vaccine“ can only do it’s job through the process of “vaccination“, so approaching the whole “vaccine trust” and convincing people to take it is also a challenge.



Let’s keep the numbers easy for the sake of simplicity and clarity at 50/50. Let’s say half of the general population (non prioritized) will choose to get vaccinated, and half won’t, then what does that look like...

Would you guys say that’s a fair baseline to start with? Would any of you venture to guess if you think more people WILL take the vaccine vs. NOT take the vaccine, or vice versa?


Another thing, IIRC, Dr. Swaminathan said that 6 months is recommended/required for Stage 3 Trials (wrt COVAX). I do recall some of those beginning in June, so that would be on point for some (need to refresh which ones).

However, maybe I dreamed this, but I could’ve sworn I read/saw something the other night re: some of the US’ latest vaccines - that it/they had a reduced phase 3 time of only 2 months, note to check USA FDA JS EUA vaccination notes. Jmo, moo, not sure about this.



Pfizer and BioNTech Conclude Phase 3 Study of COVID-19 Vaccine Candidate, Meeting All Primary Efficacy Endpoints | Pfizer
November 18, 2020

What I think will happen is that news will show stories about "outliers". The .01% that may have the worst side effects. That is what will swing people away from a vaccine in droves. Even now, people are suspect that the current administration bypassed many protocols to make this happen so fast.
 
  • #540

under slide 7 it says:

Take warning

The Spanish flu was highly contagious and spread easily among the population due to “inadequate quarantine measures” and a “lack of coordinated efforts from health authorities.”

Also, under slide 12. I wonder why?:

Indigenous and remote communities are hardest hit

Indigenous Canadians in isolated northern communities were some of the hardest hit by the virus. According to a 1919 federal report, “Indigenous Canadians living on reserves died from the pandemic at more than five times the national average.” The death toll was so high in the Inuit community of Okak, Newfoundland, that the settlement was abandoned in 1919.
 
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