Hi FLMom. Warfarin, the active ingredient in many rodenticides in the US is a blood thinner. In certain small doses it is used as a clot buster and preventive in humans. In larger doses it causes massive hemorrhages in cats, dogs, humans, etc... The only treatment for toxicity resulting from the ingestion of warfarin in rat poison is massive amounts of Vitamin K. This is because Vitamin K induces the growth of blood clotting factors, which over days can stop the bleeding.
The chemical in the rat poison that got into our pet's food is called, aminopterin, a protein based substance that does not cause blood thinning, which can lead to hemorrhage. We do not use aminopterin as an ingredient in rodenticides in the US anymore. However, aminopterin is used in small doses to treat cancer, psoriasis, and other autoimmune diseases in humans. It can have severe side effects and seems to tax the liver and the renal(kidney) system. It is toxic even at low levels in humans, and I am guessing that it may be even more toxic to our pets(cats more so than dogs). In the cases of aminopterin toxicity Vitamin K will not help because the problem is not bleeding, but the liver and kidneys, instead.
I speculate that one reason that it is affecting cats more than dogs is because cats have an even more difficult time processing aminopterin than dogs because their livers lack a key enzyme(s) required for that function. The enzyme theory is not fact, it is just my theory.
What saved Angel, my cat when she was in almost complete kidney failure(she didn't urinate for days, then it was a very dark brown) was force feeding her 1/2 teaspoon of Hills Science Diet A/D (not on the list, thank goodness) mixed with water, every one and a half hours, eighteen hours per day for over three weeks. I am ever grateful and so happy that she made it through and is doing very well. She gives me lots of love bites, cute kitty faces, and meows--just like her old Angel self. I feel so very sad for all of the pets who didn't make it, and I feel equally sad for those who loved them.
I hope Menu Foods follows through and evaluates for a major overall in their production and in who they get their ingredients from. Why on Earth would we be importing wheat from China when we have so much surplus wheat in the US we could about feed the world with it? That, I would like to know.
Lion
First of all, Glitch, I'm so sorry that you're having to pretty much go through this mourning period twice. *hugs* to you
First of all, let me say that I'm a semi-retired vet tech, and the last place I worked was at an animal ER.
I've read the recent reports that say that these animals died from wheat gluten that had been mixed with rat poison. I've also heard that some of the animals had been very ill, then put on IV fluids and some improved enough after a few days to go home. Right?
What's puzzling me is that I know from my vet tech background that the only way to heal an animal after they've eaten rat poison is by giving the animal Vitamin K injections, then sending them home on Vitamin K tablets. You have to give these tablets for weeks in order to make sure that the pet has no long term kidney or liver damage.
I have a friend whose dogs have gotten into rat bait TWICE over the last year or so. The first time they horked up the food at her feet and she saw the pellets in the vomitus, and the second time she had no evidence, but was highly suspicious. Even when you're just suspicious, you still go ahead with the entire routine of Vitamin K, because it won't do any harm to the dog or cat if it's not needed, because the body will just excrete what it doesn't use.
What I'm getting at is. . . .
WHY THE blankety-blank-blank am I seeing that this is suspected, but NOWHERE am I seeing ANYTHING on the news about the urgency of Vitamin K??!! :banghead:
So, if you know anyone that's been affected, call your vet and ask them, please! I know that drug companies can only ship so much so fast, and I'm hoping to hell that the drug companies don't end up with a shortage of Vitamin K from so many orders. I'm lucky with mine (they eat dry food), but if it was me I'd be at the vet's office toot-sweet getting a presciption since this is so widespread.
FLMom
(fur, feather and reptilian mother of 10)