• #101
It already is. A lab has been trying to get enough usable DNA for an SNP profile out of one of the kids for years (I think the one confirmed to be male?), and once/if they do it was going to be sent to Identifinders for the genealogy research.
So i don't have to google it... can you summarize what an SNP profile is?
And do you know the name of the Lab?
I admit much ignorance in this study, even though I want to learn much more....
 
  • #102
So i don't have to google it... can you summarize what an SNP profile is?
And do you know the name of the Lab?
I admit much ignorance in this study, even though I want to learn much more....

SNP stands for single-nucleotide polymorphism. It's a kind of genetic difference between people, and when you record lots of them together as a DNA profile it can be used as a unique genetic fingerprint to identify individuals and their genetic traits and predisposed diseases.

They require a lot more genetic material to be analyzed to create them than other standard forensic DNA tests like short-tandem repeats, but can also be generated from smaller and more damaged biological samples, and they're what's needed in order to conduct genetic genealogy by law enforcement and consumer DNA companies.

I think this recent publication by Oxford is a good overview: https://academic.oup.com/fsr/article/10/1/owae013/7625515

I'm not sure what lab Identifinders (which only does the IGG research part) was working with for this case (not that this info couldn't be public elsewhere, I'm just not aware at this time).
 
  • #103
SNP stands for single-nucleotide polymorphism. It's a kind of genetic difference between people, and when you record lots of them together as a DNA profile it can be used as a unique genetic fingerprint to identify individuals and their genetic traits and predisposed diseases.

They require a lot more genetic material to be analyzed to create them than other standard forensic DNA tests like short-tandem repeats, but can also be generated from smaller and more damaged biological samples, and they're what's needed in order to conduct genetic genealogy by law enforcement and consumer DNA companies.

I think this recent publication by Oxford is a good overview: https://academic.oup.com/fsr/article/10/1/owae013/7625515

I'm not sure what lab Identifinders (which only does the IGG research part) was working with for this case (not that this info couldn't be public elsewhere, I'm just not aware at this time).

Thanks for the article. Appreciate it.
 
  • #104
I am so glad you all have posted this recently.... bringing this case to the forefront. Again!
@strangerthanfiction1200 Can you provide the article or whatever that you read last month...
Any newer articles are so helpful.
Though it was often suspected they were both males, I don't think that was clarified in previous writings.

Vermont is just so full of interesting mysteries. Given that the state is small and the population is small, these cases stand out in the whole state, and close area (me) .
And Middlebury alone as unique stories!!
If you use google and type in 1935 and unidentified female and two children it has an option for information from the state of Vermont and goes into the detective determination to find out their names. Vermont is also included in the search engine. It also listed possible identities at that time and suspects.
 
  • #105
I am so glad you all have posted this recently.... bringing this case to the forefront. Again!
@strangerthanfiction1200 Can you provide the article or whatever that you read last month...
Any newer articles are so helpful.
Though it was often suspected they were both males, I don't think that was clarified in previous writings.

Vermont is just so full of interesting mysteries. Given that the state is small and the population is small, these cases stand out in the whole state, and close area (me) .
And Middlebury alone as unique stories!!
A google search. Unidentified female and two children from 1935 Middlebury. The article goes to the state level and has information about the detective's search for the killer (they name suspects) and possible identities and rule them out. Originally they thought that one of the remains was a female, but found her alive and adopted. She was not related to the third child that was determined to be a male.
 
  • #106
Burlington Free Press.
 
  • #107
I read the article last month, but it was published in 2016. Sorry.
 
  • #108
I know there isn’t much conversation here though I am glad to see some, but that article has a couple of statements about which there can reasonably be debate including that the dental work was essentially something most practitioners could undertake. I will attach articles counter to this today (gotta earn a living now), but I attach just for reference a February 1936 FBI circular which includes the orthodontic report as well as clear pictures of the dental work. Some of this language was reported at the time. It grabbed this report here:

 

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