Coronavirus COVID-19 - Global Health Pandemic #48

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Scott Gottlieb, MD on Twitter
Good summary of the new study on exposure to #COVID19 in Santa Clara and its limitations. In the end, likely to be case that nationally, 2-5% of the population will have been exposed to covid. Multiple studies and experts are coalescing around that range.
Up to 4% of Silicon Valley is already infected with coronavirus
5:48 PM - 17 Apr 2020

Scott Gottlieb, MD on Twitter
Louisiana showing signs of new #COVID19 cases flattening.
EV1pu0iXsAE6R_f.jpg

6:13 PM - 17 Apr 2020

Scott Gottlieb, MD on Twitter
In Wuhan scientists conducted antibody tests on 3,600 hospital employees, 5,000 visitors; shows about 2.5% positivity for exposure - surprisingly low. Accumulating evidence shows overall U.S. exposures likely to be lower than once presumed, 2-5% nationally, more in hot spots.
7:14 PM - 17 Apr 2020
 
The self therapy is going quite well I have to say.

I’m so ahead of things I’ve already identified, isolated, tested, & treated the smell of bleach as a future PTSD trigger.

(I’m so over the smell of bleach!)
 
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Hawaii closes all state beaches

[...]

Residents will still be allowed to swim and surf with social distancing, but cannot sunbathe, picnic or play games on the sand.

Ige’s order also said recreational boating is limited to two people per boat, and that watercraft should maintain a distance of at least 20 feet (6 meters). Hiking and fishing trips also are limited to two people at a time, except for relatives who live together.

[...]

Birx says it's unclear if US has coronavirus testing capability for phase two reopening

[...]

“What we will be doing is monitoring how much we have to use in phase one to really help inform phase two,” Birx said. “The really unknown in this, to be completely transparent, is asymptomatic and symptomatic spread.”

[...]

US schools can open "soon," Trump says

[...]

“I think the schools are going to be open soon, I think lot of governors are already talking about schools being opened. And we do have to take care of our seniors, because we've learned a lot about the disease. We’ve learned a lot about this plague, we have to take care of our seniors. We’re going to take care of a lot of people,” Trump said at Friday’s White House press briefing in response to a question about schools and childcare.

[...]

All airline passengers will have to wear masks or face coverings at Canadian airports

[...]

Passengers who fail to show that they have a face covering during the boarding process will not be allowed to fly.

The measures go into effect on Monday.

Coronavirus unit nurses suspended for refusing to work without N95 masks

[...]

Two nurses at Providence Saint John's Health Center in Santa Monica, California, told CNN that they, along with eight other nurses, were suspended with pay after refusing to enter coronavirus patient rooms on April 9 without N95 masks.

The hospital said no N95 masks were available and insisted they wear surgical masks instead, the nurses said — even though other healthcare workers there were provided N95 masks.

[...]

Chicago’s biggest jail has released more than a fifth of its detainees

[...]

The jail's population was over 5,000 in mid-March. The number of detainees is now roughly 4,276, according to information provided by the Cook County State’s Attorney’s Office.

In a new statement to CNN, the Sheriff’s Office said: “Hundreds of gallons of bleach and disinfectant is distributed throughout the jail weekly as well as masks and other protective gear. We’ve proactively single celled the majority of the jail population and maximized social distancing to the extent it is possible in a correctional facility, including preparing and opening previously closed detention areas."

[...]

All Walmart employees to wear face coverings

[...]

In a message from the CEOs of Walmart and its Sam’s Club wholesale stores, the company said, “We will begin requiring that associates wear masks or other face coverings at work. This includes our stores, clubs, distribution and fulfillment centers, as well as in our corporate offices.”

The statement says customers will also be encouraged to cover their faces, although it will not be mandatory.

Walmart says it will provide all employees with a face covering, or they can provide their own. The new policy goes into effect Monday.

[...]

Coronavirus live updates: Death toll rises above 150,000 worldwide - CNN
 
This is a riveting, well-written article. I read it on another site earlier. One thing to keep in mind is that many of the disease/illness processes described also occur in patients with other illnesses- the cytokine storm process and sepsis can and do occur under quite a few different circumstances.
All I am saying is that what the article describes happens in Covid patients with severe illness, but can also happen in a patient who became severely ill with a flu, for instance.
Perspective only and I certainly wouldn't wish it on anyone!
 
For websleuthers looking for something to occupy their time while staying at home:

Wanted: Someone to watch true crime documentaries all day. The pay: $1,000 - CNN

Looks like they are selecting only one person though.

Meeeeeeee!!!!!!

Lol we’d all like that gig haha

ETA:

Actually reading the article now:

"Whoever gets the job will be tasked with watching 16 documentaries, including "Manson 40 Years Later" and "Columbine Massacre: In the Killer's Mind."
The hire will have to document the whole thing, so "their followers can watch to see if they crack...or not," the website says.”

Lol. Anyone of us WSers could do that gig with our eyes closed. Moo Easy Peazy. We do it every day.
 
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Well they've set up temporary hospitals, maybe they'll set up temporary schools in order to social distance? In Ohio they had special day care provided for medical personnel' children. They were set up so each child was always at least 6 feet apart.
Wow. How did they manage that? How do you keep all the kids 6 feet apart?
 
Louisiana Gov. John Bel Edwards said the state is not ready for a Phase 1 reopening and that there is still "work to do."

Edwards, speaking at a news conference Friday, said the state has not reached the threshold that must be passed to get to the Phase 1 reopening — including not having 14 days where the number of cases, tests and deaths are moving in the right direction.

Speaking from Louisiana State University where he toured a personal protective equipment production center, Edwards said he hopes the state can get to Phase 1 within the next few weeks.

"I can't tell you that we will get to Phase 1 by May 1st, but I hope we do," he said.

"We aren’t going to be successful in opening the economy if we see a spike in cases and can’t deliver healthcare,” he added .

April 17 coronavirus news - CNN

He toured a PPE production facility? Good grief!
 
Ladies if u must pee in a bush this summer have a looky loo first. I was camping as a teen and did so in the dead of night. End result was there was barely a spot on my body that didn't have poison ivy. I was one day away from being hospitalized as the Dr. feared it going into my eyes. It didn't but it was awful. Had a bunch of shots, pills and creams. Sooo that's my public service announcement lol
Yah, we need to look first.

My cousin squatted in the woods one night, when she was at a small college party around a campfire. She walked far enough away for privacy, squatted to pee, heard a buzzing sound, and realised she was 'watering' a hornet's nest...:eek:....a painful mistake...
 
Well they've set up temporary hospitals, maybe they'll set up temporary schools in order to social distance? In Ohio they had special day care provided for medical personnel' children. They were set up so each child was always at least 6 feet apart.

Wow. How did they manage that? How do you keep all the kids 6 feet apart?

Wow, virtually “born” into social distancing...
 
Investigation of the Second Wave (Phase 2) of Severe Acute Respiratory Syndrome (SARS) in Toronto, Canada. What Happened? - PubMed
2008

“Interpretation: What was believed to be the end of the Toronto SARS outbreak led the Provincial Operations Centre (POC) to issue a directive allowing a more relaxed use of infection-control precautions during the beginning of Phase 2 of the outbreak. These relaxations of precautions were temporally associated with the nosocomial transmission of SARS to hospital staff, other patients and visitors at Hospital X. As a result of this outbreak significant changes have been made with respect to infection-control practices within Canada.”
 
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LA coronavirus testing sites open to same- and next-day testing for people with symptoms
Testing is still limited to people with symptoms and by appointment. But it speaks to the ramp-up of testing capacity in the region.

LA coronavirus testing sites open to same- and next-day testing for people with symptoms – Daily News


The strict limits on coronavirus testing across L.A. County loosened one more notch this week, as L.A. Mayor Eric Garcetti announced that the free, public centers would include same- or next-day testing to anyone in the county with symptoms of the respiratory illness.

Just a few weeks ago, such testing was restricted to vulnerable people such as seniors and people with underlying conditions.

If you’ve got symptoms — fever, cough, shortness of breath — you can apply via the city/county web portal to make an appointment for a same- or next-day test.

Over the last month, testing capacity has increased at a network of more than 27 testing sites, from northern L.A. County to Pomona to Bellflower.
 
Emerging Infections: What Have We Learned from SARS?
2004

“Given the current size and mobility of the human population, emerging diseases pose a continuing threat to global health. This threat became reality with the outbreak of severe acute respiratory syndrome (SARS). The emergence of a disease requires two steps: introduction into the human population and perpetuated transmission. Although preventing the introduction of a new disease is ideal, containing a zoonosis is a necessity. The lessons that we have learned from SARS were the topic of a meeting of The Royal Society on January 13, 2004, in London, England.

Zoonoses are responsible for most emerging infectious diseases, including infections caused by Ebola virus, West Nile virus, monkeypox, hantavirus, HIV, and new subtypes of influenza A. In the case of SARS coronavirus (SARS-CoV), serologic evidence indicates that the virus was spread through interspecies transmission from wild game markets in Guangdong, China (Malik Peiris, University of Hong Kong). This finding led to bans in the wild meat trade from Nan Shan Zhong (Guangzhou Respiratory Disease Research Institute) similar to the ban on eating nervous system tissue from cows that was implemented after new variant Creutzfeldt-Jakob disease emerged in Britain.

Ecologic changes, concomitant with increasing contact between humans and animal disease reservoirs, contribute to zoonoses. The emergence of SARS was facilitated by increased contact between people and animal disease reservoirs as the wild meat industry expanded recently. Global warming will likely contribute to the spread of dengue beyond tropical regions (Tony McMichael, National Centre for Epidemiology and Population Health, Canberra, Australia). Habitat fragmentation by deforestation may increase the contact between people and reservoir species. For example, hemorrhagic fever virus has been linked to deforestation in South America.”........

[...]

“Population heterogeneity and the network structure of human interactions will affect the spread of an emerging disease. In the 2003 SARS outbreak, healthcare workers were at particular risk (8) and acted as bridges carrying the infection from the hospital and causing community wide epidemics. High-risk "core groups" have been a major focus of HIV/AIDS models for years (9), but the movement of SARS patients into the core (i.e., the hospital) adds a further complication (3).

The two waves of SARS clusters in Toronto (Robert Maunder, Mount Sinai Hospital, Toronto) highlight the need for surveillance even after an outbreak appears extinguished. Management of the SARS epidemic also demonstrated that public service infrastructure, which affords the greatest chance of success (3), is essential to the rapid containment of an outbreak. In areas most affected, contact tracing was important (10). In Guangdong, police departments tracked down contacts of infected persons, who were then followed up for 10 days after exposure. Evaluating the surge capacity of public health services and hospitals is one way to assess the preparedness of a medical system.”

—-

Hmmm, so that article is from 2004, & mentions Guangdong.

Interesting.

Guangdong had a lot of CV cases too, just behind Hubei iirc.

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Hmmm:
Coronavirus - Global Health Emergency, 2019-nCoV #3

Seems I noted something about a market here in Guangdong, etc. on Feb. 9...hmmm Noting to review zzz goodnight
 
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It wasn't engineered but they're still investigating whether it came from the wet markets or escaped from the lab.

‘Costliest Government Coverup of All Time’: Growing Confidence among U.S. Officials That Coronavirus Emerged from Lab
By TOBIAS HOONHOUT

Coronavirus & China Coverup -- Growing Confidence Among Officials That the Coronavirus Emerged from Lab | National Review


U.S. intelligence has “increasing confidence” that the novel Wuhan coronavirus outbreak began in a lab that was researching bat-coronaviruses, contrary to China’s claim that the pandemic emerged from a Wuhan wet market, according to multiple sources that briefed Fox News.

The sources told Fox News that the initial transmission of the virus looks to be bat-to-human, and that “patient zero” contracted the disease while working at the Wuhan Institute of Virology, before going into the general population. While the lab is China’s first to achieve the highest level of international bio-research safety, known as BSL-4, its work with bats had been conducted at the lower protection level of BSL-2.

Sources also confirmed that China used the wet market theory, which was parroted by the World Health Organization, to disguise and deflect exploration into the origins of the virus. The Chinese Communist Party has restricted research into the pandemic’s origins, while documents obtained by The Washington Post this week show that in 2018, U.S. officials warned the lab’s work with bats and “shortage” of safety protocols could lead to a “future emerging coronavirus outbreak.”

show the Wuhan Institute of Virology confirming “the origin of bats of major new human and livestock infectious diseases” with new research.
 
"Fox News reported Wednesday that, according to sources, "
Here are some real sources:




NR PLUS WORLD
The Trail Leading Back to the Wuhan Labs
By JIM GERAGHTY
wuhan-coronavirus-10.jpg

Medical workers in protective suits attend to a patient inside an isolated ward of the Wuhan Red Cross Hospital in Wuhan, the epicenter of the novel coronavirus outbreak, in Hubei Province, China, February 16, 2020. (China Daily via Reuters)

The Wuhan Institute of Virology in China indeed posted a job opening on November 18, 2019, “asking for scientists to come research the relationship between the coronavirus and bats.”

Google translation of the job posting is: “Taking bats as the research object, I will answer the molecular mechanism that can coexist with Ebola and SARS- associated coronavirus for a long time without disease, and its relationship with flight and longevity. Virology, immunology, cell biology, and multiple omics are used to compare the differences between humans and other mammals.” (“Omics” is a term for a subfield within biology, such as genomics or glycomics.)

china-coronavirus-chart-2.jpg


On December 24, 2019, the Wuhan Institute of Virology posted a second job posting. The translation of that posting includes the declaration, “long-term research on the pathogenic biology of bats carrying important viruses has confirmed the origin of bats of major new human and livestock infectious diseases such as SARS and SADS, and a large number of new bat and rodent new viruses have been discovered and identified.”

china-coronavirus-chart-3.jpg


Tye contends that that posting meant, “we’ve discovered a new and terrible virus, and would like to recruit people to come deal with it.” He also contends that “news didn’t come out about coronavirus until ages after that.” Doctors in Wuhan knew that they were dealing with a cluster of pneumonia cases as December progressed, but it is accurate to say that a very limited number of people knew about this particular strain of coronavirus and its severity at the time of that job posting. By December 31, about three weeks after doctors first noticed the cases, the Chinese government notified the World Health Organization and the first media reports about a “mystery pneumonia” appeared outside China.

Scientific American verifies much of the information Tye mentions about Shi Zhengli, the Chinese virologist nicknamed “Bat Woman” for her work with that species.

Shi — a virologist who is often called China’s “bat woman” by her colleagues because of her virus-hunting expeditions in bat caves over the past 16 years — walked out of the conference she was attending in Shanghai and hopped on the next train back to Wuhan. “I wondered if [the municipal health authority] got it wrong,” she says. “I had never expected this kind of thing to happen in Wuhan, in central China.” Her studies had shown that the southern, subtropical areas of Guangdong, Guangxi and Yunnan have the greatest risk of coronaviruses jumping to humans from animals — particularly bats, a known reservoir for many viruses. If coronaviruses were the culprit, she remembers thinking, “could they have come from our lab?”



. . . By January 7 the Wuhan team determined that the new virus had indeed caused the disease those patients suffered — a conclusion based on results from polymerase chain reaction analysis, full genome sequencing, antibody tests of blood samples and the virus’s ability to infect human lung cells in a petri dish. The genomic sequence of the virus — now officially called SARS-CoV-2 because it is related to the SARS pathogen — was 96 percent identical to that of a coronavirus the researchers had identified in horseshoe bats in Yunnan, they reported in a paper published last month in Nature. “It’s crystal clear that bats, once again, are the natural reservoir,” says Daszak, who was not involved in the study.


On February 4 — one week before the World Health Organization decided to officially name this virus “COVID-19”the journal Cell Research posted a notice written by scientists at the Wuhan Institute of Virology about the virus, concluding, “our findings reveal that remdesivir and chloroquine are highly effective in the control of 2019-nCoV infection in vitro. Since these compounds have been used in human patients with a safety track record and shown to be effective against various ailments, we suggest that they should be assessed in human patients suffering from the novel coronavirus disease.” One of the authors of that notice was the “bat woman,” Shi Zhengli.

In his YouTube video, Tye focuses his attention on a researcher at the Wuhan Institute of Virologynamed Huang Yanling: “Most people believe her to be patient zero, and most people believe she is dead.”

MUCH MORE AT LINK
 
A 30-year-old woman, seemingly healthy and with no coronavirus symptoms, presented to an imaging department in Iran after losing a relative to COVID-19.

Under routine protocols this patient would not be given a chest scan, but in this instance, doctors made an exception.

Within days her CT scan, which showed markings typical of COVID-19 pneumonia, had been seen by doctors all around the world.

A seemingly healthy woman demanded a CT scan. Her lungs showed COVID-19
 
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