COVID-19 -Media, Maps, Videos, Timelines, CDC/WHO Resources, etc. ***NO DISCUSSION***

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September 28, 2020
Official coronavirus death toll is likely an 'underestimate' of the true total, WHO says

“But Mike Ryan, executive director of the WHO’s health emergencies program, said the reported numbers likely represent an “underestimate” of those individuals who have either contracted Covid-19 or died as a cause of it.

“When you count anything, you can’t count it perfectly. But I can assure you that the current numbers are likely an underestimate of the true toll of Covid,” he said during a news conference at the agency’s Geneva headquarters when asked about global deaths.“
 
W.H.O. Rejects Antiviral Drug Remdesivir as a Covid Treatment

WHO advises against Gilead's remdesivir for all hospitalised COVID-19 patients

WHO tells doctors not to use Gilead's remdesivir as a coronavirus treatment, splitting with FDA

WHO advisers recommend against Gilead’s remdesivir for treating COVID-19

WHO advises against Gilead's remdesivir for all hospitalised COVID-19 patients

WHO Advises Doctors Not to Use Gilead’s Remdesivir for Covid

WSJ / WHO Recommends Against Use of Gilead Covid-19 Drug Remdesivir
Agency says there isn’t evidence the antiviral reduces deaths or recovery times of coronavirus patients

FDA Grants EUA to Combination of Olumiant and Remdesivir in Hospitalized COVID-19 Patients | BioSpace



Additional Reference:

1 month ago
Massive WHO remdesivir study suggests no Covid-19 benefit. Doctors aren't so sure.

1 month ago


FDA approves Gilead's remdesivir as coronavirus treatment
Oct. 22


Remdesivir has ‘little or no effect’ in reducing coronavirus deaths, WHO says
Oct. 16


Oct.8
https://www.nejm.org/doi/full/10.1056/NEJMoa2007764


Gilead CEO: We're studying new ways to treat coronavirus with remdesivir outside of the hospital
Sept. 14


Gilead says remdesivir coronavirus treatment reduces risk of death in severely sick patients
July 10, 2020


CONCLUSIONS
Our data show that remdesivir was superior to placebo in shortening the time to recovery in adults who were hospitalized with Covid-19 and had evidence of lower respiratory tract infection. (Funded by the National Institute of Allergy and Infectious Diseases and others; ACTT-1 ClinicalTrials.gov number, NCT04280705



Remdesivir: the antiviral drug is being touted as a possible coronavirus treatment – but will it work?
April 30, 2020


Remdesivir: don't use drug Trump took for Covid-19, WHO says


Subscribe to read | Financial Times


US secures world stock of key Covid-19 drug remdesivir
June 30, 2020



After WHO trial failure, influential medical group advises against Gilead's remdesivir in COVID-19 critical care: Reuters
Nov 13


‘A very, very bad look’ for remdesivir
Nov 6


Russian firm seeks to produce COVID-19 drug remdesivir without patent
Nov 2


Remdesivir, which WHO found has little or no effect in reducing coronavirus deaths, shows mixed results in Nepal
2 weeks ago


Clinical Trials In North Texas Underway On An Inhaled Version Of Remdesivir For COVID-19 Treatment
Oct 26


Oct. 22
FDA Approves First Treatment for COVID-19


Oct 22
Remdesivir Doesn’t Reduce COVID-19 Deaths, a Large WHO Trial Finds


Should the FDA Have Approved Remdesivir to Treat COVID-19 Patients?
3 weeks ago


3 weeks ago / Dr. Gottlieb / FDA:
https://youtu.be/V9eAxiBNohY


Remdesivir for COVID-19: Where Does It Stand?
https://www.clinicaloncology.com/CO...sivir-for-COVID-19-Where-Does-It-Stand-/61135
Nov. 9, 2020


Differences in remdesivir efficacy likely due to trial variances, not drug
2 weeks ago


4 weeks ago

1 month ago



FDA Issues EUA for Remdesivir After Trio of Studies
May 1


Remdesivir: FDA will reportedly authorize use for Covid-19 after trial shows 'positive effect' on recovery time - CNN
April 30, 2020

 
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Antimicrobial resistance:


WHO / Antimicrobial resistance


WHO Director-General's opening remarks at the media briefing on COVID-19 - 20 November 2020

Good morning, good afternoon and good evening.

More cases of COVID-19 have been reported in the past 4 weeks than in the first six months of the pandemic.

Across Europe and North America, hospitals and ICU units are filling up or full.

This week there has been more good news from vaccine trials, which continues to give us hope of ending the pandemic. At the same time, we must continue to use the tools we have to interrupt the chains of transmission and save lives now.

The COVID-19 pandemic is a stark reminder of the intimate relationship between humans, animals and the planet we share.

We cannot protect and promote human health without paying attention to the health of animals and the health of our environment.

That’s nowhere more true than in the case of antimicrobial resistance – one of the greatest health threats of our time.

Antimicrobial resistance may not seem as urgent as a pandemic, but it is just as dangerous.

It threatens to unwind a century of medical progress and leave us defenceless against infections that today can be treated easily.

Although antibiotics are a key focus, antimicrobial resistance also includes resistance to medicines for HIV, malaria, neglected tropical diseases and more.

Wednesday marked the start of World Antimicrobial Awareness Week, an annual opportunity to raise awareness of antimicrobial resistance and encourage best practices among the general public, health workers and policy makers to slow the development and spread of drug-resistant infections.

The slogan for 2020 is "Antimicrobials: handle with care".

For years, WHO has been working with the Food and Agriculture Organization of the United Nations, and the World Organisation for Animal Health, to address antimicrobial resistance and other health issues that arise from the interaction between humans and animals with a “One Health” approach.

Our three organizations – called the tripartite – conduct regular surveys to monitor country progress on antimicrobial resistance.

Our latest report, with data from 136 countries, shows that almost 90% of countries have national action plans for antimicrobial resistance, but only 20% have identified funding for implementation.

To help address that gap, together we have established a trust fund to support low- and middle-income countries to develop a truly One Health approach to addressing antimicrobial resistance.

Thanks to the governments of the Netherlands, Sweden and the United Kingdom, to date we have raised US $13 million, which will provide the first round of support to eleven countries.

Just this week we have launched the implementation in Indonesia.

Additional funds will be required for the next round of investment.

Today the tripartite is launching a new report that examines the international instruments that govern the use of antimicrobials – and identifies gaps in regulations for use of antimicrobials in humans, animals and plants.

Together, our three organizations will work to address these gaps and generate more global coherence in the use of antimicrobials.

One of the most important ways to do that is through increased political commitment at the highest levels of government.

That’s why today we are launching the One Health Global Leaders Group, which will bring together prominent leaders from government, the private sector and civil society organizations, to advocate for urgent action to combat the threat of antimicrobial resistance.

The Group will be co-chaired by Her Excellency Sheikh Hasina, Prime Minister of Bangladesh, and Her Excellency Mia Mottley, Prime Minister of Barbados.

The Group will bring together key stakeholders in agriculture, health, development, food and feed production and other relevant areas to maintain urgency, public support, political momentum and visibility of the antimicrobial resistance challenge.

It’s now my great honour to introduce the co-chair of the One Health Leaders Group, Her Excellency Sheikh Hasina, the Prime Minister of Bangladesh, to say a few words.

Your Excellency, you have the floor and thank you for your commitment and support.

[H.E. SHEIKH MASINA MADE BRIEF REMARKS]

Thank you, Your Excellency. I would now like to introduce the other co-chair of the One Health Leaders Group, Her Excellency Mia Mottley, Prime Minister of Barbados.

Your Excellency, thank you for your commitment and support. You have the floor.

[H.E. MIA MOTTLEY MADE BRIEF REMARKS]

Thank you, Your Excellency. And I would like to also point out that you share the same name as my new granddaughter, Mia.

I’m also delighted to be joined today by my colleagues in the tripartite: Qu Dongyu, Director-General of the Food and Agriculture Organization of the United Nations; and Dr Monique Eliot, Director-General of the World Organisation for Animal Health.

Mr Qu, welcome and you have the floor.

[MR QU MADE BRIEF REMARKS]

Thank you. And now it’s my honour to introduce the Director-General of the World Organisation for Animal Health, Dr Monique Eliot.

Dr Eliot, welcome, and you have the floor.

[DR ELIOT MADE BRIEF REMARKS]

Merci beaucoup, Dr Eliot, and thank you to all our guests today. We look forward to working closely with all of you to protect the medicines that protect us.

Fadela, back to you.

[DR TEDROS MADE THE FOLLOWING REMARKS AT THE CONCLUSION OF THE BRIEFING]

Today is World Children’s Day. As our colleagues at UNICEF say, it’s a day to reimagine a better future for every child.

Although children are less at risk from severe COVID disease, children have suffered from the pandemic in many ways.

Our response to the pandemic, and the way we recover from it, will shape the world our children grow up in.

That makes it even more important to fight the pandemic with every tool at our disposal – to save lives now and give our children a better future.

I thank you.
 


Ep 32 Osterholm Update COVID-19: Stop Swapping Air
 
Exposed to Covid-19? How long you need to quarantine may soon change.
A shorter quarantine period is likely to include increased testing.

“What the eventual recommendation will be is unknown, but CDC Director Dr. Robert Redfield said in an October briefing that the agency was considering shortening the length of quarantine by up to a week.

At the time, Redfield said researchers were looking at whether "you can use testing during the quarantine to determine if you can shorten the quarantine to seven or 10 days." Without testing, he said, you could miss a percentage of infectious cases.

"Obviously we don’t want people to be quarantined 14 days unnecessarily," Redfield said.“
-more at link


WSJ News Exclusive | CDC Finalizing Recommendation to Shorten Covid-19 Quarantines
 
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“Elsewhere, there are growing concerns that the U.S. testing and contact tracing system is breaking down under the weight of steadily growing new case numbers. The Centers for Disease Control and Prevention seemed to acknowledge the challenge this week, when it released new guidance on Monday.

The agency is now advising states to prioritize people who tested positive for COVID-19 in the past six days and focus on their immediate household contacts, people living, working or visiting “congregate living facilities, high density workplaces or other settings (or events) with potential extensive transmission.”

People who test positive should self-quarantine immediately and notify their own contacts, the guidelines say.“

Hospital workers called exhausted as U.S. records highest number of COVID deaths since May
 
New CDC Report /
COVID-19 Outbreak Associated with a 10-Day Motorcycle Rally in a Neighboring State — Minnesota, August–September 2020
Weekly / November 27, 2020 / 69(47);1771-1776

COVID-19 Outbreak Associated with a 10-Day Motorcycle Rally ...

“What is added by this report?

Following a 10-day motorcycle rally in South Dakota attended by approximately 460,000 persons, 51 confirmed primary event-associated cases, 21 secondary cases, and five tertiary cases were identified in Minnesota residents. An additional nine likely rally-associated secondary or tertiary cases occurred. Four patients were hospitalized, and one died. Genomic sequencing supported the associations with the motorcycle rally.“
 
5 Months Ago / Frontline PBS / The Virus: What Went Wrong? (Full Film)
 
Five questions on new data from China-WHO showing 124 confirmed coronavirus patients in December 2019 / (courtesy of @PayrollNerd)

From the above link:

“The above “Huang et al, 2020” reference is to a Lancet paper online Jan. 24 in which 41 confirmed patients (40 illness onset in December and one illness onset on Jan. 1). The ”70%” with a link to the Seafood Market were shown chronologically in the paper’s Figure 1B.

Five days later, on Jan. 29, the New England Journal of Medicine published a paper on 425 confirmed patients through Jan. 22. Figure 1 in that paper provided the timeline of illness onset for 46 patients in December.

On Feb. 17 the China CDC weekly published a detailed epidemiologic study of the epidemic with 44, 672 confirmed cases through Feb. 11. In Figure 2B here:”
 
A new study found coronavirus may have been in the US in December. That doesn't mean you'll ever know if you had it then - CNN

“A new study published Monday suggests the novel coronavirus was infecting people across the US as early as December -- a month before the first person known to have been infected with coronavirus arrived in the US from China on January 15.

Researchers screened blood donations made in December and early January and found evidence of antibodies to the novel coronavirus in at least 84 samples from nine states
-- something that would suggest those people had been infected with coronavirus.
"These findings suggest that SARS-CoV-2 may have been introduced into the United States prior to January 19, 2020," the researchers at the US Centers for Disease Control and Prevention and the Red Cross wrote in the journal Clinical Infectious Diseases.



Serologic testing of U.S. blood donations to identify SARS-CoV-2-reactive antibodies: December 2019-January 2020
Published: 30 November 2020



Virus May Have Arrived in U.S. in December, but Didn’t Spread Until Later
Dec. 1, 2020
 
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The Vaccine Confidence Project

“By listening for early signals of public distrust and questioning and providing risk analysis and guidance, we aim to engage the public early and pre-empt potential programme disruptions.“
—-

“What is the Vaccine Confidence Project™?

Vaccine confidence concerns the belief that vaccination – and by extension the providers and range of private sector and political entities behind it – serves the best health interests of the public and its constituents. The Oxford English Dictionary defines confidence as “the mental attitude of trusting in or relying on a person or thing”. In light of that, we are not examining the well-studied domain of supply and access barriers to vaccination, but rather what is typically called the “demand” side of immunisation. However, our focus on confidence takes the “demand” rubric a step further than the more traditional notion of building demand through increasing knowledge and awareness of vaccines and immunisation to understanding what else drives confidence in vaccines, and the willingness to accept a vaccine, when supply, access and information are available. In other words, understanding vaccine confidence means understanding the more difficult belief-based, emotional, ideological and contextual factors whose influences often live outside an immunisation or even health programme but affect both confidence in and acceptance of vaccines.“


Some excellent resource links from the above VCP site:


Flu.gov
A centralised access point to many US government resources related to flu and flu vaccination.

HPV Prevention and Control Board
[...]

NHS Choices: Vaccinations
Quick and easy access to information about the NHS vaccination schedule, vaccine safety, and clear explanations of how vaccines work and what ingredients they contain.


US Centers for Disease Control and Prevention: Vaccines and Immunizations
This page provides an excellent, authoritative source of information on immunization schedules, side effects and safety of vaccines, and answers to many common questions.


Vaccines Knowledge Project
The VKP provides information about vaccines, their recommended schedules, ingredients and other safety concerns.


Vaccine Safety Net
The VSN, established by the WHO, is a network of resources and organizations providing scientific and accurate information about vaccine safety.

Vaccines Work: Advocacy for Immunisation
“This is a space for those who are working to improve immunisation systems and access to vaccines, particularly in resource-poor settings. It aims to help you to find ideas, resources and guidance to advocate for strengthened commitment to vaccines and immunisation to save lives.”

WHO Global Vaccine Safety
Information on vaccine safety and the Global Vaccine Safety Initiative (GVSI) from the World Health Organization.



“VCP Mission

The purpose of the project is to monitor public confidence in immunisation programmes by building an information surveillance system for early detection of public concerns around vaccines; by applying a diagnostic tool to data collected to determine the risk level of public concerns in terms of their potential to disrupt vaccine programmes; and, finally, to provide analysis and guidance for early response and engagement with the public to ensure sustained confidence in vaccines and immunisation. This initiative also defines a Vaccine Confidence Index™ (VCI) as a tool for mapping confidence globally.”

More about the mission of VCP:
VCP Mission — The Vaccine Confidence Project
 
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WHO Director-General's opening remarks at the Member States briefing on COVID-19 - 3 December 2020
3 December 2020 | source
Honourable Ministers, Excellencies, dear colleagues and friends,

Good morning, good afternoon and good evening.

Today’s briefing will start with an update from Dr Anders Nordstrom, head of the secretariat of the Independent Panel for Pandemic Preparedness and Response, to be followed by a question and answer period, as Tim said.

Dr Nordstrom will brief you on the Independent Panel’s fact-finding work on the impacts of the pandemic and its engagement with stakeholders.

The Panel’s next meeting will take place on the 16th and 17th of December, and will provide an update to the Executive Board in January.

After that, you will hear an update on vaccines and the COVAX Facility from Dr Kate O’Brien, the Director of Immunization, Vaccines and Biologicals, along with WHO Chief Scientist Dr Soumya Swaminathan, and Dr Mariângela Simão, the Assistant Director-General for Access to Medicines and Health Products.

Last week, Dr Swaminathan and Dr O’Brien provided an update on results from several COVID-19 vaccines and on country readiness and delivery support.

Today we will continue that discussion, updating you on the regulatory approval of the vaccines, access to vaccines, and the COVAX Facility.

As you may know, yesterday the United Kingdom became the first country to approve a vaccine with demonstrated efficacy for COVID-19.

It is incredible to think that less than a year ago, we had not even heard of this virus, and now we have an approved vaccine against it.

WHO has an unwavering commitment to equitable, timely and fair access to all the tools that can serve to mitigate and end this pandemic, including vaccines.

There is a great deal of work to do in each country to make that a reality. In the beginning, of course, vaccine quantity will be limited, but will increase over the course of 2021.

This means that not all countries will receive doses at exactly the same time, but as supplies increase, countries will receive vaccines as quickly as possible.

In the meantime, we are working with countries to make sure that they are prepared to receive and deliver vaccines.

We are here, along with our partners, to do everything possible to ease the way.

I am so pleased to share that donors have answered the initial call for funding the Gavi COVAX Advanced Market Commitment target of two billion US dollars in 2020.

I would like to use this opportunity to thank you. Much gratitude.

We look forward to successfully funding the total requirements in 2021.

As always, there will be time for your questions. And we look forward to receiving your suggestions, inputs and guidance.

I thank you.
 
WHO Director-General's opening remarks at the release of the global estimates of the need for rehabilitation
WHO, IHME and The Lancet
2 December 2020 | source
My sister Senait,

Distinguished colleagues and friends,

I am so pleased to join you today for the launch of this landmark study, the very first global estimate of the need for rehabilitation services.

The demand is far, far greater than most people assume.

More than 2.4 billion people, almost a third of the global population, need these services to help them reclaim their lives and livelihoods.

Public health emergencies are an often-overlooked area where rehabilitation services are needed. After the fight to survive is won, then comes the fight to restore full health and dignity.

People living with the long-term consequences of COVID-19 have spoken to me again and again about their need for rehabilitation services, along with the need for recognition, and further research.

Those requiring rehabilitation services may include survivors of both infectious and noncommunicable disease, accidents, conflicts, and so many other health problems that arise over the course of one’s life.

The data that we are launching today show the magnitude of the challenge.

Rehabilitation services must be part of essential packages of care as part of every country’s journey towards universal health coverage.

Working together, we can build a safer, fairer, and more caring world for all of us.

I thank you.
 

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