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Great question! If the suitcase was being used regularly by JAR to transport items back and forth from the dorm to the house, then the house to Atlanta, and back again, why would JR, who said he assumed the suitcase was empty, have taken it to the basement? You would think he might want to leave it handy for JAR to use again when he came back from Christmas break to gather up things to take back to the dorm.
Then, let's ask this: Did JAR bring home a soiled duvet from the dorm, set the suitcase in the laundry area, expecting the housekeeper to check thru it, and then wash the comforter for him and replace it back into the suitcase? If that was a pattern, it would explain why it was in the laundry area on the second floor. But then, all the more reason NOT to move the suitcase to the basement, rather you would think it would be kept there to reload with the clean bedding, and then set back into the bedroom for JAR to pick up when going back to school.
Better yet, if JR had moved the suitcase 3 months earlier, as was stated in one of his interviews, and it still had a duvet in it that was soiled, wouldn't JAR have looked for his dorm comforter by then? Why would he bring home a soiled comforter, if not to wash it, planning to take it back to the dorm? If he wasn't going to use it again, and planned to just replace it with a new one (which is what he would have had to do since 3 months had gone by), wouldn't he just have trashed it at school??
Also, JAR must not have worried about using the suitcase again to take back and forth to Atlanta over the holidays. JR claimed to have moved it 3 months prior to the crime, and since it was found in the train room, JAR must have been using alternative luggage for his travels. He must have brought home the soiled duvet from his dorm room, decided to replace the soiled one with a new one, and never gave another thought to his old one being shuffled off to the basement in his suitcase that he also decided he'd never have to use again anyway.