12:45pm
The trial is now resuming after a short lunch break.
12:50pm
Ben Myers KC, for Letby's defence, is now asking Professor Hindmarsh questions.
He said the fast-acting insulin would not be visible.
Professor Hindmarsh confirms that type of insulin would have a "distinctive smell" about it.
Mr Myers says the concentration of insulin administered could, over time, could lead to complications for the patient.
Prof Hindmarsh: "That is correct."
12:57pm
Mr Myers said it would be about 25 minutes before the insulin administered would have its effect.
Prof Hindmarsh said it would take about 25 minutes for it to have its biggest effect.
Mr Myers says other than the heart rate and vomiting, Child F did not appear to suffer any other physical symptoms than the low blood sugar levels.
He asks, given the high level of insulin seen, would there be "more powerful, physical consequences?"
Prof Hindmarsh says vomiting is not an unusual feature.
In the magnitude of features, he says, the effects would be on brain function rather than any other peripheral manifestations.
He said physical features of hypoglycaemia would "not be easy to pick up in a newborn, or a premature" baby.
"Neurologically, that's different."
The features would also be "extremely variable".
The first symptom "could, and would often be, collapse and seizure".
Mr Myers says it is an alleged 17-hour period of exposure of high levels of insulin, and if the effects would have been more apprarent.
Prof Hindmarsh says high levels of insulin have been recorded in babies with underlying conditions, and they present well up to the point of collapse.
The trial is now resuming after a short lunch break.
12:50pm
Ben Myers KC, for Letby's defence, is now asking Professor Hindmarsh questions.
He said the fast-acting insulin would not be visible.
Professor Hindmarsh confirms that type of insulin would have a "distinctive smell" about it.
Mr Myers says the concentration of insulin administered could, over time, could lead to complications for the patient.
Prof Hindmarsh: "That is correct."
12:57pm
Mr Myers said it would be about 25 minutes before the insulin administered would have its effect.
Prof Hindmarsh said it would take about 25 minutes for it to have its biggest effect.
Mr Myers says other than the heart rate and vomiting, Child F did not appear to suffer any other physical symptoms than the low blood sugar levels.
He asks, given the high level of insulin seen, would there be "more powerful, physical consequences?"
Prof Hindmarsh says vomiting is not an unusual feature.
In the magnitude of features, he says, the effects would be on brain function rather than any other peripheral manifestations.
He said physical features of hypoglycaemia would "not be easy to pick up in a newborn, or a premature" baby.
"Neurologically, that's different."
The features would also be "extremely variable".
The first symptom "could, and would often be, collapse and seizure".
Mr Myers says it is an alleged 17-hour period of exposure of high levels of insulin, and if the effects would have been more apprarent.
Prof Hindmarsh says high levels of insulin have been recorded in babies with underlying conditions, and they present well up to the point of collapse.