She went out on Monday at about 7.30pm for an 8pm night shift. He left at about 8.30pm and took the bus to Paddington, we now know. She tried to call from work twice, once at 10ish (rang unanswered), once at 11ish (didn't ring, provider later told her it was turned off). She returned the next morning at 8.30am-ish then went to bed and woke up again about 2pm, when she realised he was not at home and probably hadn't been all night. She became alarmed at about 5pm and called the locksmith and the police.
I was confused too but she gave an interview which is linked upthread and all these timings are gone through in order.
It's particularly awful that the police were so slack at first, I think, because she seems to have been so on the ball - alerting the phone provider to try and establish his whereabouts/status, checking if he'd taken wallet, medicine etc. She did all the right things and just got fobbed off and insulted for her trouble.
She says he had a lock on his door "for privacy". I think it's odd myself. I have sons of a similar age and would be concerned by that tbh, though obviously I do respect their privacy. Under the circumstances, there may be more to it in Richard's case, but many here have said they think it's pretty normal, so hey.
HTH
