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That would be a good question to have a good answer to; unfortunately, it's hard to know without having research results on that specific product. Caffeine may increase pregnancy risks, but not at a much higher rate than expected and not consistently in studies. As with any ingestion in pregnancy, best to avoid anything not known to be safe and medically indicated.
What would you advise a Lupus patient in her first trimester to do? Abstain from wearing the patch altogether? Thank you.