I can tell you what I wouldn't convict on:
--prosecution's Hanna-Barbera tranq gun theory (voluntarily withdrawn when they realized it's actually impossible with the alleged weapon)
--the dog handler's testimony (witness voluntarily withdrawn when prosecution realized he wasn't testifying how they expected--quite the opposite! For anyone curious, look it up in the case record. The handler is on police bodycam at the bike scene stating the dog followed her scent along the creek. Please think for yourself about the implications to the case with this one.)
--the idea that LE can pinpoint a suspect's location to the degree they can follow him around a residential property and re-construct a murder based on historical cell tower data in a semi rural area and/or GPS. Or even better, a timeline based on a truck events.
There's more, too much to list, but ultimately I never felt they had a coherent case beyond he was home at specific times, she disappeared, and there was marital discord. People harp on about his lies and inconsistencies, but the fact is every person lies or gets tripped up when interrogated, that's the entire point of it. Yes, innocent people do "lie" to cops all the time, it's why innocent people need representation most of all. He was questioned by local LE and FBI for what, 30 hours without an attorney present? The only noteworthy things about that are 1) he didn't stop before requesting an atty and 2) they didn't squeeze out a confession from him in all that time.
Nothing we saw prior to the trial would be enough, if I'm sitting on that jury, for me to convict on first degree murder and send someone to prison with LWOP and only one is needed. Hearsay and circumstantial evidence, sure, but circumstantial evidence can be painted any way you want. Combine it with confirmation bias and it's a bad mix. They need to find her remains, although I suspect any future prosecution will run into many of the same issues unless something more concretely damning is unearthed.