afitzy
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More confusion on NSAIDs it seems:
Is Ibuprofen Really Risky for Coronavirus Patients?
Quotes from article:
Is Ibuprofen Really Risky for Coronavirus Patients?
Experts are puzzling over a claim made by France’s health minister.
The health minister of France, Olivier Véran, has issued a blunt warning about painkillers taken by people ill with the coronavirus: Stay away from drugs like ibuprofen and aspirin.
Take acetaminophen instead, he advised in a tweet on Saturday. So-called nonsteroidal anti-inflammatories like ibuprofen worsened symptoms of the illness caused by the coronavirus, he said.
Olivier Véran
✔@olivierveran
#COVIDー19 | La prise d'anti-inflammatoires (ibuprofène, cortisone, ...) pourrait être un facteur d'aggravation de l’infection. En cas de fièvre, prenez du paracétamol.
Si vous êtes déjà sous anti-inflammatoires ou en cas de doute, demandez conseil à votre médecin.
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10:38 AM - Mar 14, 2020
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Some patients had experienced serious adverse effects while taking Nsaids, the health ministry said in a bulletin to doctors, and Nsaids should never be used in these patients.
The advice left many medical experts scratching their heads. The coronavirus is a new pathogen, and little is known about the disease it causes, called Covid-19, or how patients respond to common medications.
Dr. Véran’s warning followed a letter published in The Lancet this month. The letter’s authors proposed that certain drugs increase the number of so-called ACE2 receptors on the surfaces of cells.
The coronavirus uses these receptors to infect cells, the authors noted, and so in theory patients taking the drugs might be more vulnerable to the virus. One of the drugs was ibuprofen.
Get an informed guide to the global outbreak with our daily coronavirusnewsletter.
But there was no research to back up the contention. “No data,” said Dr. Michele Barry, director of the Center for Innovation in Global Health at Stanford University. There is no reason to think that infected patients should avoid temporary use of ibuprofen, she added.
“It’s all anecdote, and fake news off the anecdotes,” said Dr. Garret FitzGerald, chair of the department of pharmacology at the Perelman School of Medicine at the University of Pennsylvania. “That’s the world we are living in.”
“Until there is evidence, there is no reason at all to be issuing public health guidance” about Nsaids and the coronavirus, he added.
There are reasons to worry about long-term, heavy use of Nsaids, which have been linked an increased risk of kidney damage in some patients. People taking blood thinners also should avoid Nsaids.
But for infectious disease specialists, the greater concern is that when Nsaids and acetaminophen reduce fever, patients may be more comfortable but their lower temperatures can short-circuit the body’s main defense against infection.
Studies have found that if people infected with a variety of viruses and other microorganisms bring their fevers down, with Nsaids or with acetaminophen, their symptoms may last longer and they continue to shed virus for a longer time — meaning they may be contagious for longer periods.
“Everything that walks, flies, crawls or swims on the face of this earth makes fever,” said Dr. Paul Offit, an infectious disease expert at the University of Pennsylvania and Children’s Hospital of Philadelphia. Even lizards, he added, which crawl to the top of rocks and sun themselves when they are ill to bring their temperatures up.
The immune system works better when the body’s temperature is higher, enabling it to more efficiently kill viruses and bacteria. Dozens of studies — in animals, reptiles and humans — have found that fever is beneficial in fighting infections.
But there is a trade-off. For every 1 degree centigrade that the body’s temperature rises, the metabolic rate increases by 12 percent. “We don’t want to pay that metabolic price when we don’t have to, so we only make a higher temperature when we need it,” Dr. Offit said.
++++++++++++++++++++++++++++++++++++++++++
WHO Now Officially Recommends to Avoid Taking Ibuprofen For COVID-19 Symptoms
Quotes from article:
WHO Now Officially Recommends to Avoid Taking Ibuprofen For COVID-19 Symptoms
AFP
17 MARCH 2020
The World Health Organization recommended Tuesday that people suffering COVID-19 symptoms avoid taking ibuprofen, after French officials warned that anti-inflammatory drugs could worsen effects of the virus.
The warning by French Health Minister Veran followed a recent study in The Lancet medical journal that hypothesised that an enzyme boosted by anti-inflammatory drugs such as ibuprofen could facilitate and worsen COVID-19 infections.
Asked about the study, WHO spokesman Christian Lindmeier told reporters in Geneva the UN health agency's experts were "looking into this to give further guidance."
"In the meantime, we recommend using rather paracetamol, and do not use ibuprofen as a self-medication. That's important," he said.
He added that if ibuprofen had been "prescribed by the healthcare professionals, then, of course, that's up to them."
His comments came after Veran sent a tweet cautioning that the use of ibuprofen and similar anti-inflammatory drugs could be "an aggravating factor" in COVID-19 infections.
"In the case of fever, take paracetamol," he wrote.
The French minister stressed that patients already being treated with anti-inflammatory drugs should ask advice from their doctor.
Paracetamol must be taken strictly according to the recommended dose, because too much of it can damage the liver.
The COVID-19 pandemic, which has infected around 190,000 people worldwide and killed more than 7,800, causes mild symptoms in most people, but can result in pneumonia and in some cases severe illness that can lead to multiple organ failure.
Is Ibuprofen Really Risky for Coronavirus Patients?
Quotes from article:
Is Ibuprofen Really Risky for Coronavirus Patients?
Experts are puzzling over a claim made by France’s health minister.
The health minister of France, Olivier Véran, has issued a blunt warning about painkillers taken by people ill with the coronavirus: Stay away from drugs like ibuprofen and aspirin.
Take acetaminophen instead, he advised in a tweet on Saturday. So-called nonsteroidal anti-inflammatories like ibuprofen worsened symptoms of the illness caused by the coronavirus, he said.
Olivier Véran
✔@olivierveran
Si vous êtes déjà sous anti-inflammatoires ou en cas de doute, demandez conseil à votre médecin.
40.5K
10:38 AM - Mar 14, 2020
Twitter Ads info and privacy
44.9K people are talking about this
Some patients had experienced serious adverse effects while taking Nsaids, the health ministry said in a bulletin to doctors, and Nsaids should never be used in these patients.
The advice left many medical experts scratching their heads. The coronavirus is a new pathogen, and little is known about the disease it causes, called Covid-19, or how patients respond to common medications.
Dr. Véran’s warning followed a letter published in The Lancet this month. The letter’s authors proposed that certain drugs increase the number of so-called ACE2 receptors on the surfaces of cells.
The coronavirus uses these receptors to infect cells, the authors noted, and so in theory patients taking the drugs might be more vulnerable to the virus. One of the drugs was ibuprofen.
Get an informed guide to the global outbreak with our daily coronavirusnewsletter.
But there was no research to back up the contention. “No data,” said Dr. Michele Barry, director of the Center for Innovation in Global Health at Stanford University. There is no reason to think that infected patients should avoid temporary use of ibuprofen, she added.
“It’s all anecdote, and fake news off the anecdotes,” said Dr. Garret FitzGerald, chair of the department of pharmacology at the Perelman School of Medicine at the University of Pennsylvania. “That’s the world we are living in.”
“Until there is evidence, there is no reason at all to be issuing public health guidance” about Nsaids and the coronavirus, he added.
There are reasons to worry about long-term, heavy use of Nsaids, which have been linked an increased risk of kidney damage in some patients. People taking blood thinners also should avoid Nsaids.
But for infectious disease specialists, the greater concern is that when Nsaids and acetaminophen reduce fever, patients may be more comfortable but their lower temperatures can short-circuit the body’s main defense against infection.
Studies have found that if people infected with a variety of viruses and other microorganisms bring their fevers down, with Nsaids or with acetaminophen, their symptoms may last longer and they continue to shed virus for a longer time — meaning they may be contagious for longer periods.
“Everything that walks, flies, crawls or swims on the face of this earth makes fever,” said Dr. Paul Offit, an infectious disease expert at the University of Pennsylvania and Children’s Hospital of Philadelphia. Even lizards, he added, which crawl to the top of rocks and sun themselves when they are ill to bring their temperatures up.
The immune system works better when the body’s temperature is higher, enabling it to more efficiently kill viruses and bacteria. Dozens of studies — in animals, reptiles and humans — have found that fever is beneficial in fighting infections.
But there is a trade-off. For every 1 degree centigrade that the body’s temperature rises, the metabolic rate increases by 12 percent. “We don’t want to pay that metabolic price when we don’t have to, so we only make a higher temperature when we need it,” Dr. Offit said.
++++++++++++++++++++++++++++++++++++++++++
WHO Now Officially Recommends to Avoid Taking Ibuprofen For COVID-19 Symptoms
Quotes from article:
WHO Now Officially Recommends to Avoid Taking Ibuprofen For COVID-19 Symptoms
AFP
17 MARCH 2020
The World Health Organization recommended Tuesday that people suffering COVID-19 symptoms avoid taking ibuprofen, after French officials warned that anti-inflammatory drugs could worsen effects of the virus.
The warning by French Health Minister Veran followed a recent study in The Lancet medical journal that hypothesised that an enzyme boosted by anti-inflammatory drugs such as ibuprofen could facilitate and worsen COVID-19 infections.
Asked about the study, WHO spokesman Christian Lindmeier told reporters in Geneva the UN health agency's experts were "looking into this to give further guidance."
"In the meantime, we recommend using rather paracetamol, and do not use ibuprofen as a self-medication. That's important," he said.
He added that if ibuprofen had been "prescribed by the healthcare professionals, then, of course, that's up to them."
His comments came after Veran sent a tweet cautioning that the use of ibuprofen and similar anti-inflammatory drugs could be "an aggravating factor" in COVID-19 infections.
"In the case of fever, take paracetamol," he wrote.
The French minister stressed that patients already being treated with anti-inflammatory drugs should ask advice from their doctor.
Paracetamol must be taken strictly according to the recommended dose, because too much of it can damage the liver.
The COVID-19 pandemic, which has infected around 190,000 people worldwide and killed more than 7,800, causes mild symptoms in most people, but can result in pneumonia and in some cases severe illness that can lead to multiple organ failure.
diaper leaks. I do sometimes put my purse there, or even a food product, but it is disgusting when you think about it. Yes, you're right, you have to wipe down your purse often.
