Controversial drug hydroxychloroquine to be given to coronavirus patients in Australia
Australia are going to start using malaria drug to treat CV19 patients
"A controversial anti-malaria drug will be given to Australian Covid-19 patients in hospitals outside of clinical trials, the federal government confirmed, after the
therapeutic goods registration requirements for two drugs were waivedto allow them to be imported to and stockpiled in Australia.
The drugs, hydroxychloroquine and chloroquine, are being explored in clinical trials around the world for their potential as a coronavirus treatment to ease symptoms, or as a preventative drug to stop people being overcome with the infection. Trials are exploring use of the drugs on their own as well as in combination with others.
But clinicians
have warned that hydroxychloroquine can cause severe and even life-threatening side-effects, and have cautioned against using it for conditions for which it has not been tested. It is a proven treatment for malaria and for some autoimmune conditions.
Studies on its efficacy as a Covid-19 preventative or treatment are mixed. Much of the focus on the drug came after a small French study, which has since been widely
disputed and been found to have omitted data contain spurious results. A small study from China
found no benefit to chloroquine being given to Covid-19 patients.
Hydroxychloroquine
has also caused division within the White House, Axios reported, after the US president, Donald Trump, hyped it as a “game changer” in treating the virus. The White House infectious disease expert warned Trump that evidence for
the drug was only anecdotal and far from proven.
A health department spokesman said the inclusion of the medicine in the national medical stockpile was based on not only its proven clinical uses, but on its potential clinical utility in the absence of a well-documented treatment.
While “clinical trials are critical for ensuring the safety and effectiveness of potential treatments, before they are made available through the health system”, the spokesman said, the drug would be made available not only for clinical trials but “for use in hospitals for ill patients”.
The government said under an emergency exemption to therapeutic goods registration requirements the drug would be sourced from overseas and imported, including intermediates and other raw materials so that local manufacturing could occur.
The department confirmed that the former federal politician Clive Palmer, who has said he will produce 1m doses of the drug, has a prior written arrangement with the commonwealth and so his plan aligned with the emergency exemption.
“It is anticipated that medicines containing hydroxychloroquine sulfate will be made available to the national medical stockpile from a number of pharmaceutical companies,” the spokesman said. “Some of these include generous donations funded by Mr Clive Palmer.”
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