Coronavirus COVID-19 - Global Health Pandemic #60

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  • #161
https://www.thelancet.com/journals/...6736(20)31282-4/fulltext#.XtpLybzuliE.twitter


Early evidence of pronounced brain involvement in fatal COVID-19 outcomes
The first cases of COVID-19 in Germany were confirmed in the greater Munich area and isolated in our hospital.

Subsequently, more than 690 patients were admitted for inpatient care, 103 of whom were transferred to the intensive care unit (ICU). 63 patients died in hospital. 587 patients recovered and were discharged.


Older patients with comorbidities are considered most at risk of death; however, there are reports of rapid decline and subsequent death in younger patients with no known comorbidities

.\ Pulmonary and heart failure are considered the primary causes of COVID-19-associated death, but the precise pathology of disease progression is unknown. Moreover, recent reports describe irregularities in coagulation for a subset of patients.
1
Here we report the findings of autopsies of six patients (four men and two women, aged 58–82 years) who died from COVID-19 in April, 2020.

*continued at link
 
  • #162
A new grand baby and a wedding! :)

How many people? Are any moderate to high risk that are invited? I’m thinking immediate family members only?
Late July will be hot. So you might have people wanting to go inside to get out of the sun or cool off? And use the restroom in your house?

: ) my first grandson : )

We’re thinking that it will be about 10 people total will make it, most of whom are my daughters best friends through school and college. Maybe the grooms Mom, and a couple of my friends.
We’re going to have one person (oldest daughter) pre package some light food using small trays with a cover (like what you get take out food in). That will alleviate the food serving issue. Going to out beverage stands outside/with ice and have beverages.
We will all be wearing masks and staying 6 ft. apart.
The bathroom will have bleach and cleaners accessible, and paper towels. Crossing fingers.
Still working on the other things.
She spent weeks in New York at the Javits center working (Army), so I really want to make this as memorable and fun as can be. : )
 
  • #163
My son and soon to be DIL had been planning their wedding for July 15, 2 year anniversary of first date. They've decided to still have it but in their yard with just family. No more than 10 guests allowed. He asked my FIL to perform the service so now all the close family can be there. Both FIL and MIL would've put us over 10 but since FIL is the minister (instead of guest) the numbers work out.
 
  • #164
Coronavirus breakthrough as vaccine ‘using inhaler could be ready by August'

Coronavirus breakthrough as vaccine ‘using inhaler could be ready by August'

Bradley Jolly
7 hrs ago
...
A vaccine for coronavirus could be ready in the form of an inhaler in just weeks, it is believed.

Researchers at University of Oxford are "80 per cent confident" the Covid-19 vaccine they've been developing will work, particularly on younger people.

Drug company Astra Zeneca will produce two billion doses of the vaccine when it gets the green light, it is reported today.
He said: “We are guessing that might be around about August time - it might be before if cases do not decline as quickly as we expect, or be later if we run out of cases."

He added the drug will be in the form of an inhaler, it is understood.

The trial, which started in April, began recruiting up to 10,260 adults over 55 and children.
Since then, Astra Zeneca has already agreed to supply 100 million doses of the potential vaccine to the UK. The Anglo-Swedish company has also signed a massive $1 billion deal for a coronavirus vaccine with the US government.
Wonder what the microchip conspiracy theorists will come up with to explain why this is bad.
 
  • #165
A sign of how restaurants are desperately trying to stay in business - Cracker Barrel, the Christian-owned chain which historically omitted alcohol on it's beverage list is now experimenting with adding beer, wine and mimosas to the menu:

Forget the biscuits! You may soon be ogling over some of the new alcoholic menu items at Cracker Barrel restaurants.

The southern roadside staple is testing beer, wine and flavored mimosas at 20 locations across Florida as well as in Kentucky and Tennessee, reports Food and Wine.

Mimosas and dumplings: Cracker Barrel testing out alcohol menu in Florida

Cracker Barrel is my guilty pleasure when I go to Florida. I'd be happy to have a glass of wine with my Chicken Fried Chicken!
4370.gif
 
  • #166
https://nypost.com/2020/06/08/who-asymptomatic-spread-of-coronavirus-appears-to-be-very-rare/

WHO: Asymptomatic spread of coronavirus appears to be ‘very rare’

June 8, 2020 |

People who have the coronavirus but don’t display symptoms aren’t driving the spread of the pandemic, World Health Organization officials said Monday.

“From the data we have, it still seems to be rare that an asymptomatic person actually transmits onward to a secondary individual,” Dr. Maria Van Kerkhove, head of WHO’s emerging diseases and zoonosis unit, said at a news briefing in Geneva, CNBC reported.

“It’s very rare.”

Health officials warned early on that asymptomatic carriers could be fueling the spread by stealth –but Van Kerkhove said that while asymptomatic spread can occur, it is not the main way the virus was being transmitted.

“We have a number of reports from countries who are doing very detailed contact tracing,” she said.

“They’re following asymptomatic cases. They’re following contacts. And they’re not finding secondary transmission onward. It’s very rare,” she said.

Governments should instead focus their efforts on detecting and isolating infected people with symptoms — then tracking anyone who might have come into contact with them, she said.

“What we really want to be focused on is following the symptomatic cases,” Van Kerkhove said.

[ So maybe it is effective to take peoples temps before they enter a building?]
 
  • #167
Wonder what the microchip conspiracy theorists will come up with to explain why this is bad.
I would worry because it was created so fast. How long did they test it and how many people did they test it on? Sure was quick.*

Most experts said it would take at least a year and a half for a viable and safe vaccine to be created and tested before hitting the market.

How did this one happen so fast?

ETA-*
The trial, which started in April, began recruiting up to 10,260 adults over 55 and children.
Since then, Astra Zeneca has already agreed to supply 100 million doses of the potential vaccine to the UK. The Anglo-Swedish company has also signed a massive $1 billion deal for a coronavirus vaccine with the US government.


*the trial began in April, and this is first week of June, and they are ready to give it out to millions of people already? :confused:
 
  • #168
A sign of how restaurants are desperately trying to stay in business - Cracker Barrel, the Christian-owned chain which historically omitted alcohol on it's beverage list is now experimenting with adding beer, wine and mimosas to the menu:

Forget the biscuits! You may soon be ogling over some of the new alcoholic menu items at Cracker Barrel restaurants.

The southern roadside staple is testing beer, wine and flavored mimosas at 20 locations across Florida as well as in Kentucky and Tennessee, reports Food and Wine.

Mimosas and dumplings: Cracker Barrel testing out alcohol menu in Florida

Cracker Barrel is my guilty pleasure when I go to Florida. I'd be happy to have a glass of wine with my Chicken Fried Chicken!
4370.gif
Mimosas at CB! Woohoo
 
  • #169
This sounds promising as Astra Zeneca is a well known pharmaceutical company here in the UK. Even more promising that the US have already bought into it.

An inhaler is a good idea, but I wonder if it's single dose or something that has to be taken longer term.
My question is, how did they start the trial in April. And then declare it safe by June 6th?

Is that long enough to declare it safe and effective?
 
  • #170
Hi everyone :)

I've been reading all along, every single day. I know I don't say much. I'm the same way in person.

Want you guys to know that I feel all of your worries and pains and I'm sending hugs and positive thoughts to all.

It's been a rough week for me. Maybe that's why I'm posting. Probably is.

I totally know that things could be so much worse, so on top of everything else I'm feeling, I feel like I shouldn't feel the way I do.

My grandpa passed away earlier this week. He lived a long, good life. He was in a care home. He was blind. My mom was able to visit him once a week during his last weeks. She had to gear up in all the PPE. The care home did a great job. He didn't die from the virus, but somehow I feel like it was the cause. He went downhill fast when he wasn't able to have contact with family and friends (not blaming the care center...they did the right thing. They had positive cases in the home from both residents and care givers so they had to)

Just needed to write this all out.

Hugs to all.

condolences-messages-feature-e1546885134401.jpg
 
  • #171
So there still won't be enough Remdesivir available if the second wave begins October - December, next 'flu season'.
This is what scares me as I work with two coughers every day.
 
  • #172
My question is, how did they start the trial in April. And then declare it safe by June 6th?

Is that long enough to declare it safe and effective?

They said it should be ready by August and they’re about 80% sure it’s effective

Researchers at University of Oxford are "80 per cent confident" the Covid-19 vaccine they've been developing will work, particularly on younger people.

Drug company Astra Zeneca will produce two billion doses of the vaccine when it gets the green light, it is reported today.
He said: “We are guessing that might be around about August time - it might be before if cases do not decline as quickly as we expect, or be later if we run out of cases."

A lot of healthcare workers signed up for trials, so perhaps all those that took it haven’t fallen ill despite being around virus patients?

It does seem soon, but I’m hopeful.
 
  • #173
Interesting article. It makes sense to me, because it would appear there were cases in Europe and US months earlier than "official" cases in either Europe or US. So it stand to reason if there were cases in China months earlier than first official cases there.
"Dramatic spikes in auto traffic around major hospitals in Wuhan last fall suggest the novel coronavirus may have been present and spreading through central China long before the outbreak was first reported to the world, according to a new Harvard Medical School study."
Satellite data suggests coronavirus may have hit China earlier: Researchers

Bam. There it is. This is what I’ve been looking for / BBM:

“Using techniques similar to those employed by intelligence agencies, the research team behind the study analyzed commercial satellite imagery and "observed a dramatic increase in hospital traffic outside five major Wuhan hospitals beginning late summer and early fall 2019," according to Dr. John Brownstein, the Harvard Medical professor who led the research.

Brownstein, an ABC News contributor, said the traffic increase also "coincided with" elevated queries on a Chinese internet search for "certain symptoms that would later be determined as closely associated with the novel coronavirus."”
 
  • #174
They said it should be ready by August and they’re about 80% sure it’s effective

Researchers at University of Oxford are "80 per cent confident" the Covid-19 vaccine they've been developing will work, particularly on younger people.

Drug company Astra Zeneca will produce two billion doses of the vaccine when it gets the green light, it is reported today.
He said: “We are guessing that might be around about August time - it might be before if cases do not decline as quickly as we expect, or be later if we run out of cases."

A lot of healthcare workers signed up for trials, so perhaps all those that took it haven’t fallen ill despite being around virus patients?

It does seem soon, but I’m hopeful.
The trial participants not being infected with CV is one important thing. But what about the longterm effects of the vaccine?

I also heard that the reason it takes awhile to test a new medicine is that they need to make sure it doesn't have any longterm side effects. They couldn't possibly know that in 2 months.
 
  • #175
Question: if you expose yourself to CV19 with no mask, no social distancing, whose fault is it if you get it? Rhetorical.
 
  • #176
  • #177
  • #178
Long article on how multigenerational families, living together is a high risk for coronavirus spread - worse it says, than high density cities. Title of article is somewhat misleading, because they also have examples of multigenerational families living together in urban centers like Los Angeles County and others.

Covid-19 Stalks Large Families in Rural America
 
  • #179
When you read (in the article) the progress of Covid 19, it is horrid.
Stay safe guys!

'It feels endless': four women struggling to recover from Covid-19

'It feels endless': four women struggling to recover from Covid-19

Luke Harding
8 hrs ago
...
Last month, the Guardian published an interview with Paul Garner, a professor of infectious diseases, about his experience of Covid-19. The piece was shared widely and viewed nearly 1m times. Readers got in touch to say they too were suffering from lingering and often strange Covid-19 symptoms.

There is evidence that the official NHS description of the virus’s symptoms – cough, fever, loss of taste/smell – is too narrow. Those who do not need acute hospital treatment and who are isolating at home report a far broader range of problems. Often these go on for longer than 14 days. An online survey of 151 medical professionals who fell ill in March found 68 are still unable to work. A further 26 went back, only to stop again when symptoms returned.
It appears coronavirus may be a chronic condition. How long it persists for is unknown. The symptoms can be serious and wide-ranging, affecting the lungs, heart, brain, kidneys, stomach and nervous system. Headaches, shortness of breath, sore throat and feeling exhausted are common. So is recovery followed by frequent relapses. Here are the stories of four women who are struggling to return to normal life.

Just read this story, thanks for posting. It's frightening to think of the illness dragging on, waxing and waning, symptoms changing from day to day or week to week. These stories add to my determination to avoid getting the virus.

I posted another article from The Atlantic a few days ago that is related:
COVID-19 Can Last for Several Months
Thousands Who Got COVID-19 in March Are Still Sick
The disease’s “long-haulers” have endured months of debilitating symptoms—and disbelief from doctors and friends.

There are some good links in this article too.
 
  • #180
O m g o_O:confused::mad:
no wonder some people don’t take this seriously. Still different / conflicting info coming out every day
I thought this (asymptotic spread) was a huge concern. :rolleyes:



https://nypost.com/2020/06/08/who-asymptomatic-spread-of-coronavirus-appears-to-be-very-rare/

WHO: Asymptomatic spread of coronavirus appears to be ‘very rare’

June 8, 2020 |

People who have the coronavirus but don’t display symptoms aren’t driving the spread of the pandemic, World Health Organization officials said Monday.

“From the data we have, it still seems to be rare that an asymptomatic person actually transmits onward to a secondary individual,” Dr. Maria Van Kerkhove, head of WHO’s emerging diseases and zoonosis unit, said at a news briefing in Geneva, CNBC reported.

“It’s very rare.”

Health officials warned early on that asymptomatic carriers could be fueling the spread by stealth –but Van Kerkhove said that while asymptomatic spread can occur, it is not the main way the virus was being transmitted.

“We have a number of reports from countries who are doing very detailed contact tracing,” she said.

“They’re following asymptomatic cases. They’re following contacts. And they’re not finding secondary transmission onward. It’s very rare,” she said.

Governments should instead focus their efforts on detecting and isolating infected people with symptoms — then tracking anyone who might have come into contact with them, she said.

“What we really want to be focused on is following the symptomatic cases,” Van Kerkhove said.

[ So maybe it is effective to take peoples temps before they enter a building?]
 
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