Coronavirus COVID-19 - Global Health Pandemic #88

[margarita25]

An Aussie friend of mine has been taking a little Yes/No survey on FB.

So far:

22 say yes they will have the vaccine right away
4 say no
5 say they will wait for a while, see how it goes

Ftr, I am planted very firmly in the “wait camp”, jmo, which is why I’m especially grateful to have this platform and collective academic discussions as we move forward into the vaccination phases in real time, together.

Again, my big question is if I dreamed this “2 months” business referred to in my above post wrt Phase 3 Trials. IF I did not dream this, then IMO, based on what I remember Dr. Swaminathan saying about safety and efficacy and 6 months needed during Phase 3, I will not be confident.

Let’s go ahead and address the elephant in the room. What we have seen unfold this last year DOES play a role IMO in whether or not I feel “safe” and “trusting” about taking these vaccines, JMO.

Do I trust what the American CDC, FDA, Pharmaceutical Companies etc. say/do? No, I don’t. Sorry. Not under the current pressure and fiasco/debacle I’ve seen this last year. Do I trust the COVAX Facility and WHO? Absolutely. That’s what I’m going to be gauging all this against, Dr. Swaminathan, etc.

I’ve studied all this enough this year to know that vaccines do save lives, and are crucial to ending this pandemic/achieving herd immunity, and that anti-vaxing can be dangerous, but I am going to wait, and choosing to remain in my bubble until more data is gathered and studied.

—

Eta / Noting pick up here:

True or False: FDA EUA allows for the length of recommended time of Stage 3 Trials to be reduced from 6 months (as mentioned by Dr. Swaminathan wrt COVAX) to 2 months (which I may have dreamed).

 

[SouthAussie]

What a year. We started off the year with horrendous widespread bushfires that burned up so much of our eastern states.
Then covid hit and brought more death and destruction.

Now we are battling bushfires again in NSW. 62 of them.


There are 62 grass and bushfires currently burning across the state, according to the NSW Rural Fire Service (RFS).
"Here we go again. We have of course seen the first weekend of really significant bushfire activity," Mr Elliott said.
"I want to make sure the message is very, very clear. What we are seeing this weekend is pretty consistent with what we will potentially see over the course of this fire season."
Dozens of fires burning across NSW as cool change hits Sydney after sweltering day

 

[nightowl1975]

There are infinite references why distribution/rollout and vaccination is expected to the general public next year, some second, third quarter - one factor is prioritized vaccination for healthcare workers and more vulnerable groups. There are also logistical aspects. We also have an escalated situation now where facilities are becoming overloaded and nurses are tending to covid patients, as indicated in last night’s discussion. It is a huge endeavor to vaccinate this many people.

There was zero comprehension of “logistics” when criticizing how long it took testing to get rolled out. So it’s curious to me listening to the reasons that taking many, many months to give people a shot is somehow different and acceptable. I guess it depends on how one chooses to look at it.

 

[SouthAussie]

There was zero comprehension of “logistics” when criticizing how long it took testing to get rolled out. So it’s curious to me listening to the reasons that taking many, many months to give people a shot is somehow different and acceptable. I guess it depends on how one chooses to look at it.

The delay in testing had nothing to do with logistics. It had everything to do with the fact that the US govt agencies chose to design their own covid test, instead of using the one that was already in existence and everyone else used.

Then the US developed covid test was FDA approved and then found to be faulty. Causing massive delays.

We have spoken of this in length back in the threads.

This whole thing has been a nightmare for the US from Day One, due to govt bureaucracy. First the denial "it's going to go away", then the faulty tests that were developed and shipped all over the country, then the lack of federal leadership ... it just goes on and on.


The World Health Organization (WHO) has shipped testing kits to 57 countries. China had five commercial tests on the market 1 month ago and can now do up to 1.6 million tests a week; South Korea has tested 65,000 people so far. The U. S. Centers for Disease Control and Prevention (CDC), in contrast, has done only 459 tests since the epidemic began.
The rollout of a CDC-designed test kit to state and local labs has become a fiasco because it contained a faulty reagent. Labs around the country eager to test more suspected cases—and test them faster—have been unable to do so. No commercial or state labs have the approval to use their own tests.
The United States badly bungled coronavirus testing—but things may soon improve | Science | AAAS

 

[ilovewings]

Sepsis is a killer. My 85 year old mil ignored a UTI because she wanted to go to a wedding, and got very ill the next day and was hospitalized with sepsis. She died two weeks later. The moral of the story...never ignore a UTI.

That’s certainly a happy ending for the man in the story. So glad he made it, but what an ordeal!

Three years ago i was hospitalzed with sepsis from a UTI i didnt know i had--
no symptoms-- i went to the ER with a very rapid heart rate--diagnosed with atrial
fibrillation-- i was admitted cause they couldnt get my heart rate under control-
I was admitted to the hospital and told i had a Had UTI--so get this---they drew
blood and wanted to rule out infection--me, thinkng i am so smart convinces
the hosp italist to discharge me-- i tell him no way do i have sepsis--so i go home
feeling kinda lousy and i get a call from the hospital later that night telling me
i have sepsis--- i had to back to the hospital for IV antibiotic treatment for 3_days
and on oral antibiotics when i got home---

 

[dixiegirl1035]

Three years ago i was hospitalzed with sepsis from a UTI i didnt know i had--
no symptoms-- i went to the ER with a very rapid heart rate--diagnosed with atrial
fibrillation-- i was admitted cause they couldnt get my heart rate under control-
I was admitted to the hospital and told i had a Had UTI--so get this---they drew
blood and wanted to rule out infection--me, thinkng i am so smart convinces
the hosp italist to discharge me-- i tell him no way do i have sepsis--so i go home
feeling kinda lousy and i get a call from the hospital later that night telling me
i have sepsis--- i had to back to the hospital for IV antibiotic treatment for 3_days
and on oral antibiotics when i got home---

Whoa, you are one lucky person! Glad you didn't have to use your angel wings back then.

 

[margarita25]

And there’s already a shortage of medical staff as they’re currently (and moreso in the next month or two) busy handling the patients from the recent (and upcoming) surges.
maybe medical retirees would be more inclined to come back to work and give shots rather than dive into a covid unit somewhere.

The fact that we are going into this new phase from hell with broken, overworked, under supported health workers, and understaffed hospitals, etc., etc. does not paint a rosy picture...add to that our elevated baseline with current exponential spread in just about every State, and record level hospitalizations PLUS MILLIONS of people traveling...today, as a matter of fact. Iirc, it was estimated this would be the busiest day (looking for link). Anyway, I am hoping for the best but expecting nothing less than catastrophic residual effects in some areas. One of the good things we do have going for us, is some experience with the virus. However, it must also be noted that patients (both covid and non-covid) just will just not be able to get the full level of care...will nosocomial transmission occur, etc., etc...There are infinite repercussions and trickling that occurs.

That reminds me, on last night’s NBC News video, they showed hospitals setting up beds in “lobbies and parking garages”. It was out of Wisconsin I think it was, and the images flashed me right back to Wuhan. Remember when they built those hospitals...

Eta / Hmm, this looks interesting / bookmarking to my hundreds of unread articles list )

Whatever Happened To ... The Instant Hospitals Built For COVID-19 Patients In Wuhan?
September 10, 2020 / NPR

 

[acutename]

IMO because 380 million is a very, very, very large number. And it's possible people will need more than 1 jab.

Maybe a factory can quickly produce 380 million paper clips, but 380 million (or potentionally 760 million) doses of a highly sensitive biomedical product that must be manufactured to extremely rigorous standards and subject to very high quality control (oops, that batch of 5000 doses was substandard, oh well, mistakes happen).

Then it needs to be administered. How many people are there to administer this vaccine? You can't just diy or just hire college kids. Lets say, 20,000 nurses can be recruited to just do that. That means each nurse has to do 17,500 doses. Can you imagine administering 17,500 shots? How many per day can one person do? I have no idea. But I don't think each person could do 500 per day, which would get it done in a month.

national guard administers it- they are also developing a "vaccine gun" which will jab multiple people. It has a sterilizing element so that they do not have to manufacture individual vials/ pre-filled syringes, etc. Think "MASH," not your local pharmacy.

www.wnpr.org › post › vaccine-approvals-loom-us-fun...
Nov 19, 2020 — ... The Island Next Door · Sharing America · Guns & America · Sports ... The Connecticut company makes a disposable injection device that it says can be ... She said the fact that the administration has placed such a large bet on a ... part of the vaccine manufacturing process — producing glass vials, filling ...

 

[margarita25]

Rsbm / BBM:

She said the fact that the administration has placed such a large bet on a ... part of the vaccine manufacturing process — producing glass vials, filling ...

This reminds me, there was talk of/concern about (potential?) shortages a while back re: the “glass vials”...noting to check current status.

(Eta: please feel free anyone to input on any of my “notings” I can’t keep up with ).

 

[24Roses]

Iowa numbers today and recent news: As of 10:00-11:00 a.m., we had 2,013 new "confirmed cases for a total of 227,796 confirmed cases of which 131,099 are recovering (+1,092). 15 more were reported to have passed for a total of 2,375. 131 were hospitalized in the last 24 hrs. for a total of 1,175 (-46). There are 96,697 active positive cases according to KWWL. Nov. 29: 2,013 new cases, 1,092 more recoveries, 15 deaths
access Daily case totals updated at 11:00 a.m.
Reports: State's new software is causing issues with contact tracing
Currently 282 Iowa inmates, 92 prison staff have COVID-19

 

[margarita25]

Hmmm, possible answer to my earlier question re: Phase 3 Trials / This is obviously not 6 months, see BBM:

Pfizer and BioNTech Conclude Phase 3 Study of COVID-19 Vaccine Candidate, Meeting All Primary Efficacy Endpoints | Pfizer

““We are grateful that the first global trial to reach the final efficacy analysis mark indicates that a high rate of protection against COVID-19 can be achieved very fast after the first 30 µg dose, underscoring the power of BNT162 in providing early protection,” said Ugur Sahin, M.D., CEO and Co-founder of BioNTech. “These achievements highlight the potential of mRNA as a new drug class. Our objective from the very beginning was to design and develop a vaccine that would generate rapid and potent protection against COVID-19 with a benign tolerability profile across all ages. We believe we have achieved this with our vaccine candidate BNT162b2 in all age groups studied so far and look forward to sharing further details with the regulatory authorities. I want to thank all the devoted women and men who contributed to this historically unprecedented achievement. We will continue to work with our partners and governments around the world to prepare for global distribution in 2020 and beyond.”

The Phase 3 clinical trial of BNT162b2 began on July 27 and has enrolled 43,661 participants to date, 41,135 of whom have received a second dose of the vaccine candidate as of November 13, 2020. Approximately 42% of global participants and 30% of U.S. participants have racially and ethnically diverse backgrounds, and 41% of global and 45% of U.S. participants are 56-85 years of age. A breakdown of the diversity of clinical trial participants can be found here from approximately 150 clinical trials sites in United States, Germany, Turkey, South Africa, Brazil and Argentina. The trial will continue to collect efficacy and safety data in participants for an additional two years.

Based on current projections, the companies expect to produce globally up to 50 million vaccine doses in 2020 and up to 1.3 billion doses by the end of 2021. Four of Pfizer’s facilities are part of the manufacturing and supply chain; St. Louis, MO; Andover, MA; and Kalamazoo, MI in the U.S.; and Puurs in Belgium. BioNTech’s German sites will also be leveraged for global supply.

Pfizer is confident in its vast experience, expertise and existing cold-chain infrastructure to distribute the vaccine around the world. The companies have developed specially designed, temperature-controlled thermal shippers utilizing dry ice to maintain temperature conditions of -70°C±10°C. They can be used be as temporary storage units for 15 days by refilling with dry ice. Each shipper contains a GPS-enabled thermal sensor to track the location and temperature of each vaccine shipment across their pre-set routes leveraging Pfizer’s broad distribution network.

Pfizer and BioNTech plan to submit the efficacy and safety data from the study for peer-review in a scientific journal once analysis of the data is completed.“

 

[nightowl1975]

There are infinite references why distribution/rollout and vaccination is expected to the general public next year, some second, third quarter - one factor is prioritized vaccination for healthcare workers and more vulnerable groups. There are also logistical aspects. We also have an escalated situation now where facilities are becoming overloaded and nurses are tending to covid patients, as indicated in last night’s discussion. It is a huge endeavor to vaccinate this many people.

There was zero comprehension of “logistics” when criticizing how long it took testing to get rolled out. So it’s curious to me listening to the reasons that taking many, many months to give people a shot is somehow different and acceptable. I guess it depends on how one chooses to look at it.

The delay in testing had nothing to do with logistics. It had everything to do with the fact that the US govt agencies chose to design their own covid test, instead of using the one that was already in existence and everyone else used.

Then the US developed covid test was FDA approved and then found to be faulty. Causing massive delays.

We have spoken of this in length back in the threads.

This whole thing has been a nightmare for the US from Day One, due to govt bureaucracy. First the denial "it's going to go away", then the faulty tests that were developed and shipped all over the country, then the lack of federal leadership ... it just goes on and on.


The World Health Organization (WHO) has shipped testing kits to 57 countries. China had five commercial tests on the market 1 month ago and can now do up to 1.6 million tests a week; South Korea has tested 65,000 people so far. The U. S. Centers for Disease Control and Prevention (CDC), in contrast, has done only 459 tests since the epidemic began.
The rollout of a CDC-designed test kit to state and local labs has become a fiasco because it contained a faulty reagent. Labs around the country eager to test more suspected cases—and test them faster—have been unable to do so. No commercial or state labs have the approval to use their own tests.
The United States badly bungled coronavirus testing—but things may soon improve | Science | AAAS

I work in healthcare in the US, directly with covid patients. I assure you there were absolutely logistical nightmares getting testing ramped up. We ran out of swabs. We ran out of reagent. And on and on.

There is also some question as to the validity of whether or not the US was actually offered test kits, but of course that doesn’t necessarily feed the narrative some are determined to believe.

Perhaps this WHO lady is a bald-faced liar, though I’m not sure what the motivation would be for her to do so.

“No discussions occurred between WHO and CDC about WHO providing COVID-19 tests to the United States,” said WHO spokesperson Margaret Harris. “This is consistent with experience since the United States does not ordinarily rely on WHO for reagents or diagnostic tests because of sufficient domestic capacity.”



Biden Falsely Blames Trump Administration For Rejecting WHO Coronavirus Test Kits (That Were Never Offered)

 

[ilovewings]

Whoa, you are one lucky person! Glad you didn't have to use your angel wings back then.

i was very lucky after being so foolish as to leave the hospital thinking i could not possibly
have sepsis

 

[margarita25]

The delay in testing had nothing to do with logistics. It had everything to do with the fact that the US govt agencies chose to design their own covid test, instead of using the one that was already in existence and everyone else used.

Then the US developed covid test was FDA approved and then found to be faulty. Causing massive delays.

We have spoken of this in length back in the threads.

This whole thing has been a nightmare for the US from Day One, due to govt bureaucracy. First the denial "it's going to go away", then the faulty tests that were developed and shipped all over the country, then the lack of federal leadership ... it just goes on and on.


The World Health Organization (WHO) has shipped testing kits to 57 countries. China had five commercial tests on the market 1 month ago and can now do up to 1.6 million tests a week; South Korea has tested 65,000 people so far. The U. S. Centers for Disease Control and Prevention (CDC), in contrast, has done only 459 tests since the epidemic began.
The rollout of a CDC-designed test kit to state and local labs has become a fiasco because it contained a faulty reagent. Labs around the country eager to test more suspected cases—and test them faster—have been unable to do so. No commercial or state labs have the approval to use their own tests.
The United States badly bungled coronavirus testing—but things may soon improve | Science | AAAS

This is also addressed/explained iirc in the following documentary “American Pathogen“, as well as possibly the CDC Thread.

 

[gngr~snap]

MIS-C-
Here we are complaining about toilet paper shortages.
Even IF they got the virus under control, there still is very likely to be an organ donation shortage.
Those who had hoped the survived COVID may continue to die over several years.
There simply won't be enough kidneys and livers and hearts to go around.
MOO

 

[Cool Cats]

The Good News Coronavirus

People healed from coronavírus
43.5M

Mission
The Covid-19 crisis points out, naturally, to a hopeless moment. There are so many negative aspects that we forget that there are amazing news: number of healed people, searches for a vaccine in an unprecedented speed, collaboration between international community and civil society, that is why we need to expand our point of view.

And that’s why “The Good News Coronavirus” was created: to be a light of hope to those who feel drowned in an ocean of bad news, in spite of being important to the pandemic preventions, cause nothing but anxiety and despair.

Through this portal, the society will know that there is a world of possibilities and that the defeat of the coronavirus will be in history as the moment that we got connected and built a better future....."

 

[LadyL]

There was zero comprehension of “logistics” when criticizing how long it took testing to get rolled out. So it’s curious to me listening to the reasons that taking many, many months to give people a shot is somehow different and acceptable. I guess it depends on how one chooses to look at it.

[bbm]

where/by who???

 

[pocketaccent]

Ftr, I am planted very firmly in the “wait camp”, jmo, which is why I’m especially grateful to have this platform and collective academic discussions as we move forward into the vaccination phases in real time, together.

Again, my big question is if I dreamed this “2 months” business referred to in my above post wrt Phase 3 Trials. IF I did not dream this, then IMO, based on what I remember Dr. Swaminathan saying about safety and efficacy and 6 months needed during Phase 3, I will not be confident.

Let’s go ahead and address the elephant in the room. What we have seen unfold this last year DOES play a role IMO in whether or not I feel “safe” and “trusting” about taking these vaccines, JMO.

Do I trust what the American CDC, FDA, Pharmaceutical Companies etc. say/do? No, I don’t. Sorry. Not under the current pressure and fiasco/debacle I’ve seen this last year. Do I trust the COVAX Facility and WHO? Absolutely. That’s what I’m going to be gauging all this against, Dr. Swaminathan, etc.

I’ve studied all this enough this year to know that vaccines do save lives, and are crucial to ending this pandemic/achieving herd immunity, and that anti-vaxing can be dangerous, but I am going to wait, and choosing to remain in my bubble until more data is gathered and studied.

—

Eta / Noting pick up here:

True or False: FDA EUA allows for the length of recommended time of Stage 3 Trials to be reduced from 6 months (as mentioned by Dr. Swaminathan wrt COVAX) to 2 months (which I may have dreamed).

My own doctor is also going to wait a while, for himself and before recommending to his patients. He wants to see more longer term data. so I'm in your camp also.

 

[margarita25]

Very long list of latest google results under “covid nurse”:

Seattle nurse to servce on Biden-Harris COVID-19 advisory board | KOMO
Sunday, November 29th 2020

Need a COVID-19 Nurse? That’ll Be $8,000 a Week

As thousands of athletes get coronavirus tests, nurses wonder: What about us?
—

ICU nurse's take on 'How It Started ... How It's Going' meme goes viral - CNN Video
—

WakeMed Cary nurse: Isolation, deaths the reality of COVID-19 spike :: WRAL.com
—

'She did it for the people': Family mourns nurse who died from COVID-19
—

Column: 'Why won't Black folks trust us' on COVID-19? These doctors and nurses have answers
—

Kamala Harris Calls Chicago Nurse on Thanksgiving to Thank Her for Working on COVID-19 Frontlines
—

Salem nurse on leave after posting TikTok video flouting coronavirus rules
—

Traveling Crisis Nurse Fears Post-Holiday COVID-19 Surge
—

Digital Exclusive – COVID-19 claims life of 27-year-old nurse, family mourns loss | KVEO-TV
—

‘It’s bad. It’s really bad’: Anchorage nurses under pressure as COVID-19 pushes busy hospitals to the brink
—

Chicago nurse treating COVID-19 patients gets Thanksgiving phone call from Vice President-elect Kamala Harris: ‘I know that it’s personal for you’
—

Former El Paso nurse shares experience working with COVID-19 patients | BorderReport
—

Long-time Nashville nurse dies after contracting COVID-19 | WJHL | Tri-Cities News & Weather
—

Cleveland Clinic-Akron General ICU nurse catches COVID-19, is hospitalized but documents her journey with the virus
—

Illinois ICU nurse's plea to take COVID-19 seriously goes viral
—

South Carolina nurse goes to Montana to help frontlines of COVID-19 spike | WCIV
—

As coronavirus raged, assistant nurse manager led staff through exhaustion, fear, heartbreak
—

Nurse who came out of retirement to train others dies from COVID-19 | SiouxlandProud | Sioux City, IA | News, Weather, and Sports
—

Regis College accelerated nursing program remote during COVID
—

Nurse on Front Lines of COVID-19 Battle Faces Personal Fight Against Virus
—

Nebraska nurse dies of COVID-19 as cases surge
—

Minnesota nurse's story about her battle with COVID-19 goes viral
—

Alabama Hospitals lack nurses for COVID-19 surge
—
Nurses and doctors now face ‘fear of the known’ as COVID-19 brings people to the hospital
—
Air Force Nurses look to ease the pressure on overburdened Altru staff | Grand Forks Herald
—
Covid Combat Fatigue: ‘I Would Come Home With Tears in My Eyes’

 

[nightowl1975]

[bbm]

where/by who???

IMO? MSM. Here. There. Everywhere. Take your pick. It’s fascinating to see, then to see what I do daily at work. That’s all.