From what I am reading, they are concentrating their studies about a 3rd covid shot on the immunocompromised (and that is who these comments are about, the immunocompromised, just to be clear).
It appears some people develop no, or very few, antibodies after two doses of the vaccine.
Of 30 vaccinated
(organ transplant recipients) patients, six people had low levels of antibodies that recognized the coronavirus before getting a third dose. Another 24 did not have detectable antibodies. Two weeks after their third shot, all six patients with initially low antibody levels now had high amounts. Of the 24 people without antibodies, 16 still didn’t develop any, two had low levels and six developed high levels of antibodies.
Another study showed that 67 out of 99 organ transplant recipients vaccinated with Pfizer’s jab
had detectable antibodies after a third dose ..... That’s compared with four of 101 individuals after a first dose and 40 of 99 after a second. Of the 59 people who didn’t have antibodies after the second dose, 26, or 44 percent, mounted the immune proteins after the extra dose.
More than 75 percent of blood, or hematopoietic,
stem cell transplant recipients had detectable antibodies after two doses ..... Those who had received the transplant more than a year before getting vaccinated, and who had high numbers of pathogen-fighting white blood cells, were more likely to have lots of antibodies.
Of 12 dialysis patients who initially didn’t generate antibodies after two vaccine doses,
half mounted an antibody response after an extra shot
https://www.sciencenews.org/article...oster-shots-vaccines-immunocompromised-people
