Msbetsy,
Have you read the detectives books on this case? Such as Steve Thomas and James Kolar? They actually worked on the case, I highly recommend these books as they certainly help answer alot of questions. The DNA they are testing I believe is touch DNA in the brand new size 12 underpants that P bought which could easily be from a factory worker so I wouldn't expect a break in the case anytime soon.
At some point after the investigation was reopened in 2010, the DA did say experts believed the sample was from two people rather than one.
In 2016 they announced that the DNA would be sent to CBI to develop a stronger profile of the killer. They had consulted with the Bode Technology group who recommended testing items for touch DNA.
In the Press Release by the DA's office in 2008, Lacy said the waste band was chosen because evidence pointed to the killer having removed and/or replaced them. Genetic material was recovered from both sides. It matched the unknown DNA previously found on the underwear. From these samples they planned to develop a stronger profile.
Also in the press release, she refers to the DNA as the "unexpected 3rd party DNA" having no innocent reason to be there, so maybe the 'expected' DNA belongs to a family member or the factory worker. It refers to the "killer," singular. So there are two DNA samples but both are of the same man, as I understand it.
In the article announcing the Ramsey case going to the Cold Case Team of experts next year, it said evidence included the analysis of almost 1000 DNA samples, although I've no idea who those people could be. They’ve stated the 'unexpected' DNA doesn't belong to any POI's.
I think they are looking for one man, whose DNA would not have been on Jon Benet's clothing for any innocent reason.
I don’t know why the authors of the books indicated it was touch DNA found on size 11 underpants they are testing. Do they mean in addition to the sample found in the drops of blood on the underwear? Are they involved in the current investigation?
The touch DNA (skin cells) found on both sides of waistband of the long johns were found several years after the unknown DNA was found on her underwear and was a match.
I wouldn't expect a break in the case soon either. But I do believe one day they will find her killer. Many cold cases have been solved with DNA evidence.