It's not necessary to wait for a "break" in the case, because we already know more than enough to bring John Ramsey to trial. Regardless of whether you believe John did it or Patsy did or Burke did it, there is no longer any question of an intruder, this was an inside job, John was obviously very deeply involved, and a convincing circumstantial case can be made for him as both the molester and murderer of his daughter. See my most recent blog post for details: http://solvingjonbenet.blogspot.com/
If in fact Patsy or Burke was actually the killer (which I very much doubt), then John would have the choice of sticking with his intruder defense and going on trial or making some sort of plea bargain in which he agrees to tell all in return for a relatively light sentence or even no sentence at all, due to the statute of limitations. To get off so lightly, however, he would need to provide either direct evidence or convincing eyewitness testimony and his version of what happened would need to be backed up by his son, Burke.
The problem is NOT the need for a break in the case, but the need for a break in the timid and in fact cowardly and morally questionable attitude of the Boulder County DA. Throwing up your hands and saying "Oh this case is much too complicated, totally intractable, we'll be wondering for years about what actually happened" is both absurd and unjustifiable. A criminal trial is not about "what actually happened" but "who actually committed the crime." Now that we know for sure, thanks in part to Kolar's book, that there was no intruder, there is no longer any excuse to give John Ramsey the benefit of the doubt. He must be arrested and made to face the consequences of his crimes.
The obvious parallel is to Jerry Sandusky, who was also coddled for years, because, after all, "who really knew what happened and isn't he such a nice guy."
I think the chance of a conviction is minimal. JR was "ruled out" and I think it will be hard to discredit the "experts". Not that I think the experts have much credibility, but the jury will. JR can blame it all on PR claiming he just helped in the coverup because he didn't want her to go to prison, and that's if the jury isn't buying the intruder theory, which I think they would.
Kolar's analysis of the dna may be convincing to those of us following the case, but a jury will still lap up the "intruder" theory, based on DNA. In fact giving them 5 or 6 samples of "artifact" dna will just confuse the situation all the more, and make them even less likely to find JR guilty.
He's also been "exonerated" and unfortunately that's stronger than being "unexonerated".
Even a confession won't put an end to it because as I said in an earlier post, JR could be covering for BR, or vice versa.