Nancy Guthrie, although having ambulatory difficulties, does not appear to be a feeble shut in. Just looking at photos she must have an eye doctor/optometrist, personal physician, drug store/pharmacy, hair & nail salon (the salons always have the latest info and know when a woman is "uncomfortable" with current life), gas up her vehicle, church activities, dog grooming/food (Lrg black poodle), vet appts.
The constant appeal, "she needs her medication"... does that give anyone else the feeling it is an appeal to the abductor's humanity? Maybe even a message to someone who has cared for or should have cared for Nancy or another elderly relative in the past? Pushing thoughts.... a male who lived/cared for his elderly parent in the past? Oh Lord what ever has occurred: "You don't have to be the cause of her death. Just call us and tell us where she is." Such haunting words. I hope they are heard.