Coronavirus COVID-19 - Global Health Pandemic #43

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<modsnip> hydroxychloroquine is a generic drug. It’s out of patent, anyone can make it. Any shortages are extremely temporary since any approved maker can and are and will make as many as necessary. If it actually ends up working to treat COVID19 it’s like the best case imaginable since it’s GENERIC and cheap and safe and readily available. That’s why people want THIS to work and not some new untested privately developed drug.<modsnip>
 
I don’t have a problem with a drug being used to see if it will help people who are in serious and life threatening situations under the care of medical professionals. My concern is about people believing it is a miracle cure based on positive statements an individual (who is not a doctor or medical expert) has said on tv and them potentially obtaining it online or by other means when they should not be taking it.
Those people that do that usually are quick to plant that "money" tree because Tom Jones down the road said it helped him get out of debt.:D
In other words, people are going to do whatever it is they can to be healthy or rich no matter if it is a proven method or not. Many people should not be on pain pills but they do that everyday by buying them off the street. I see your concern, but there is really no way to get through to those people looking for a miracle in medicines or material things.
 
My daughter in Osaka (Japan) just dm'd me with a rant about how companies in the city are *not* encouraging people to self-isolate and work from home. There's no pressure on businesses to switch to remote work or shut down. Friends of hers in web design aren't even being allowed to work from home even though it would be simple to do so.

Of course it makes me fearful for her safety. Thankfully she's taking precautions and her company is now on 100% remote work. But I still worry. :(
 
My daughter in Osaka (Japan) just dm'd me with a rant about how companies in the city are *not* encouraging people to self-isolate and work from home. There's no pressure on businesses to switch to remote work or shut down. Friends of hers in web design aren't even being allowed to work from home even though it would be simple to do so.

Of course it makes me fearful for her safety. Thankfully she's taking precautions and her company is now on 100% remote work. But I still worry. :(
Wow, that's hard! At least your daughters work has gotten her isolated. That's a plus, but with no one else isolating, I would be terrified to go out for just essentials!
 
Bats are the carrier of many virus because of their immune response which makes them ideal hosts. I agree the wet markets need to halt these sales because you never know what animal is infected with what UNTIL humans consume it. Other animals, like the pangolins, can get the virus from the bats and transfer to humans. I think pangolins are linked because they have similar strains compared to the SARS COV 2. Strong similarities still don't give the answer though. I'm sure more studying of the virus is needed for anyone to conclude how this virus was transfered from animals to humans. Bats were also in connection with SARS and MERS.

Here's an interesting article regarding adding a rabies vaccine to a Covid-19 vaccine.

"Schnell has done extensive work on rabies vaccines. “We saw a lot of emergent infectious diseases were actually in areas where rabies is a big problem,” he said. So why not use the work they’d already done and apply it to other viruses?

The goal of a vaccine is to give your immune system the chance to learn what a virus looks like and prepare a response to it, even before you’re infected. To do that, vaccine developers can use either harmless fragments of a virus or an inert, chemically inactivated virus. The rabies vaccine uses an inert virus."

One recipe for a coronavirus vaccine: Add rabies
 
@Sundog thank you SO much for taking the time to give me your personal insight and perspective. I am so happy to hear about the progress being made in China with the help of new animal rights groups! A huge thank you to you, your friends and all of the activists working hard towards helping end the needless suffering of animals!
 
We were forbidden to wear masks at work, in March. Now, the CDC recommends wearing a masks, in April. Waiting for May, when we will be told to happily go back to work in our hazmat gear.

I suppose that we will need a new thread, "How to make your own hazmat suits".
 
Here's an interesting article regarding adding a rabies vaccine to a Covid-19 vaccine.

"Schnell has done extensive work on rabies vaccines. “We saw a lot of emergent infectious diseases were actually in areas where rabies is a big problem,” he said. So why not use the work they’d already done and apply it to other viruses?

The goal of a vaccine is to give your immune system the chance to learn what a virus looks like and prepare a response to it, even before you’re infected. To do that, vaccine developers can use either harmless fragments of a virus or an inert, chemically inactivated virus. The rabies vaccine uses an inert virus."

One recipe for a coronavirus vaccine: Add rabies
That is interesting! Rabies vaccine.... So that had me look up rabies. I know about it and how it is transferred but I was looking at the symptoms. It causes flue like symptoms at first.
Found that interesting also!

Centers for Disease Control and Prevention. CDC twenty four seven. Saving Lives, Protecting People
Centers for Disease Control and Prevention. CDC twenty four seven. Saving Lives, Protecting People

What are the signs and symptoms of rabies? | Symptoms | CDC
 
It is the antibiotic that is coupled with hydroxychloroquine that is not indicated for patients with heart problems. So some doctors are using a different antibiotic (not the z-pac) that is safer for those particular patients. This isn't about Trump, it is about medicine that could have a therapeutic impact on the progress of the infection.
Very true. Politics is in last place as far as priorities go and that's a'ok with me.
JMO

https://nypost.com/2020/04/04/long-island-doctor-tries-new-hydroxychloroquine-for-covid-19-patients/

Long Island doctor tries new twist on hydroxychloroquine for elderly COVID-19 patients

By Lorena Mongelli
April 4, 2020

Dr. Mohammud Alam, an infectious disease specialist affiliated with Plainview Hospital, said 81 percent of infected covid patients he treated at three Long Island nursing homes recovered from the contagion.


“In this crisis, I realized I had to do something,” Alam said. ”I realized if this was my dad, what would I do? And I would do anything I could to help.”


Alam said he decided he could not apply the touted combination of the antimalarial hydroxychloroquine and antibiotic azithromycin because the side effects could be potentially fatal for his high-risk patients, many of whom had underlying heart issues.


“I knew I could not jeopardize these patients,” Alam said.


“We know from the FDA that azithromycin can cause fatal arrhythmia and abnormal heart failure that can lead to death,” Alam said.


His patients were under long-term acute care and had comorbidities such as hypertension, coronary artery disease, chronic obstructive pulmonary disease or congestive heart failure.


The FDA has warnings that azithromycin “can cause abnormal changes in the electrical activity of the heart that may lead to a potentially fatal irregular heart rhythm.”


So instead, Alam replaced azithromycin with another decades-old antibiotic that doesn’t pose any known risks to the heart.
 
A Websleuths tip for any newbies that I find very helpful (yes, it is probably something that is super obvious and I am the only one it took a year to figure out) is if you click on the little arrow next to the poster’s name in a quoted post, it takes you back to the original quoted post. So you can easily follow back a conversation between two posters if you just click to the original quoted post.
 
I don’t have a problem with a drug being used to see if it will help people who are in serious and life threatening situations under the care of medical professionals. My concern is about people believing it is a miracle cure based on positive statements an individual (who is not a doctor or medical expert) has said on tv and them potentially obtaining it online or by other means when they should not be taking it.
Nobody has suggested it is a miracle cure but it has shown positive results and and medical experts have said it should be further explored in clinical trials so the date is tracked which is what doctors are trying to do. It has to be obtained with a prescription.

https://nypost.com/2020/04/04/long-island-doctor-tries-new-hydroxychloroquine-for-covid-19-patients/
 
A Websleuths tip for any newbies that I find very helpful (yes, it is probably something that is super obvious and I am the only one it took a year to figure out) is if you click on the little arrow next to the poster’s name in a quoted post, it takes you back to the original quoted post. So you can easily follow back a conversation between two posters if you just click to the original quoted post.
Oh golly! You just saved me a lot of work!!! Thank you for the tip!
 
Japan to boost Avigan drug stockpile as part of coronavirus stimulus | The Chronicle Herald
''TOKYO (Reuters) - Japan is considering increasing the stockpile of Fujifilm Holding Corp's Avigan anti-flu drug during this fiscal year so it can be used to treat 2 million people, according to a planning document seen by Reuters.

Local media reported on Sunday that Japan was hoping to triple the production of the drug from current levels, which is enough to treat 700,000 people if used by coronavirus patients.

Avigan, also known as Favipiravir, is manufactured by a subsidiary of Fujifilm, which has a healthcare arm although it is better known for its cameras. The drug was approved for use in Japan in 2014. Avigan is being tested in China as a treatment for COVID-19.

In the emergency stimulus package expected to be rolled out on Tuesday, the government also planned to prioritise the clinical trial process of the drug so it can be formally approved to be used in treating coronavirus patients.''
 
I think the hoarders must go to stores every single morning after the shelves are restocked and buy more TP. Even the ones with a limit run out. JMO
All day long I think. I'd bet their cars are parked outside and they have stockpiled their garages with toilet papers, hand sanitizers and disinfectant wipes. When they ran out of space, they would proceed to shove more of those items under the bed, inside the closet, over the refrigerator, in every nooks and crannies in the house. It's ridiculous. My home is in real danger of running out toilet papers in about a month. We need Hording Prevention Task Force. Seriously. IMO
 
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