Multisystem inflammatory syndrome in children (MIS-C and COVID-19)

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A COVID-related illness is sickening a growing number of children in California

BBM:

“Much is still unknown about MIS-C, including its long-term effects, whether some children are genetically predisposed to the illness and if the case count may be higher. Researchers believe that some children diagnosed between January and May with Kawasaki disease, a rare inflammatory disease that affects about 5,500 children in the U.S. each year, might have actually had MIS-C instead.

What is clear is that MIS-C cases are directly linked to a surge in COVID-19 infections — a correlation that doctors say could easily match up with a likely uptick around the holidays, given the ongoing spike in coronavirus cases. In the last week, seven additional children have been diagnosed with the syndrome across the state, according to the California Department of Public Health.

“With the number of [coronavirus] cases we’re seeing in Los Angeles now, I do expect to see more children with MIS-C coming into the hospital in the next few weeks,
” said Dr. Jackie Szmuszkovicz, a pediatric cardiologist at Children’s Hospital Los Angeles and one of Xitlali’s doctors. “We’re at a critical moment right now.”

The mysterious syndrome has killed at least 23 children in the U.S. and infected more than 1,280 — counts that have grown by more than 125% since July, according to a Times analysis of data from the CDC. The data were last reported Dec. 4 and will be updated next in January, the CDC said.“

[...]

“The state’s health department does not separate MIS-C deaths from COVID-19 fatalities. Among California’s more than 22,000 COVID-19 deaths, three have been children 17 or younger, state data show.”
 
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A COVID-related illness is sickening a growing number of children in California

BBM:

“A CDC report from August said that obesity was the most commonly reported underlying medical condition among children with MIS-C. However, two-thirds of the children diagnosed at that time did not have preexisting conditions, the report showed.

Vasquez said that Xitlali had been given a clean bill of health at her checkup in January. After her bout with MIS-C, she has developed Type 1 diabetes, which Vasquez thinks is in part because of an inflammation in her pancreas related to MIS-C.”

[...]

“Health experts say early treatment is key to mitigating the severity of MIS-C. A combination of limited information about the illness, avoidance of hospitals and doctor’s offices amid the pandemic and the fact that initial symptoms often present in the GI tract — similar to the flu — has left some children in the emergency room after mild symptoms turn severe.

“Please do not delay in seeking care for your child if they are ill,” Szmuszkovicz said. “Length of stay is going to be shorter if we can get inflammation under control earlier.””


[...]

““Our kids get sick and we want to treat them with home remedies and Tylenol without knowing that they could die without taking them to the right place,” she said.“
 
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(courtesy of @astheworldfallsdown)

Covid: Baby girl becomes Scotland's youngest death

A child under the age of one has died with Covid-19 in Scotland, official figures show.

The death of the baby girl is the youngest Covid death in Scotland and the only one under the age of 15.

National Records of Scotland (NRS) counts all death certificates that mention Covid-19, even if the person has not been tested for the virus.

The baby's death was registered between 14 and 20 December along with 202 others that week.



(* MIS-C is not mentioned specifically, but I do wonder if she developed it, jmo)
 
Covid Hospitalization Rate For Children Up 800% in 6 months
 
ACR recommends 'stepwise approach' to immunomodulatory therapy in MIS-C linked to COVID-19

Dec. 21, 2020

More than 150 California children have been diagnosed with coronavirus-related syndrome

Dec. 23, 2020

Mancelona 4-Year-Old Returns Home After Days in Hospital with MIS-C, Parkinsonism - 9 & 10 News

““It attacked almost every single organ in his body, the rash was the skin, he has a little bit of brain damage of course,” says Day.

As well as Parkinsonism, making him the only known child in the world to get the disease from COVID.

Dec. 24, 2020

Arkansas teen returns home after days battling MIS-C, a COVID-19 related illness in kids

Dec. 27, 2020

How inflammatory conditions, MIS-C and MIS-A, affect covid19 patients - Trinidad and Tobago Newsday

Dec. 28, 2020

Mother of Benton teen warns of inflammatory condition seen in children after COVID-19

Dec. 30, 2020

52 children in NC get inflammatory syndrome after COVID-19 infection

Mother of son fighting post-COVID illness urges parents to recognize MIS-C symptoms | wbir.com

“MIS-C, Abbott says, is way worse than the COVID that caused it.

“He did not have to be admitted to the hospital with COVID, where he coded here yesterday and ended up in the ICU” with MIS-C," she said.

Cook Children’s says there are four MIS-C patients in their hospital right now. At the same time, they report 18% of the children they’re testing for COVID are coming back positive; it’s a record no one wanted. “

Barron County family battles MIS-C after a mild experience with COVID-19

Dec. 31, 2020

4-year-old boy fights COVID-19 related inflammatory condition

Jan. 1, 2021

11-year-old fighting rare illness associated with COVID-19 in Texas hospital, mom says

'She would scream in pain': 7-year-old girl admitted to ICU for MIS-C after contracting coronavirus

Jan. 3, 2021

Alexandria teen on road to recovery after bout with life-threatening COVID-related illness

Jan. 4, 2021

Doctors seeing an increase in MIS-C in children | cbs8.com

Five children fight MIS-C at Texas hospital; mom tells parents to | khou.com

"”They told me here the sooner they get the kids, the less harm it will do to their bodies," Copeland said.”



Jan. 5, 2021

Flemingsburg mother warns of COVID MIS-C syndrome after 6-year-old son spent more than a week in ICU

MIS-C, a rare condition tied to COVID-19, affects southern Indiana boy


Jan. 6, 2021

Abilene boy Cason Abbott out of hospital after battle with MIS-C

Michigan health department starting to report cases of MIS-C with children


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https://www.scribd.com/document/489940175/MIS-C-Fast-Fact-Sheet-121520-711597-7

“As of December 14, 2020, there have been 43 cases of MIS-C reported in Michigan.

Of the 43 reported cases, there have been less than six deaths and 30 of the cases have been admitted to the Intensive Care Unit.

According to the Centers for Disease Control and Prevention, 47 states in the U.S. have reported at least one case of MIS-C.“

Jan. 7, 2021

Doctors alarmed at mystery illness in children with links to COVID-19

MUSC Children's Hospital using new method to treat MIS-C

“MUSC’s Shawn Jenkins Children’s Hospital has seen 14 children with MIS-C within the last year. The hospital is the first in the nation to try a new treatment for those with severe cases. The treatment is called remestemcel-L, currently in clinical trials as part of an expanded access program. The therapy uses mesenchymal stromal cells, which is made in the bone marrow of healthy people.“

Exclusive: Long Island Father Talks About Young Son's Bout With Rare COVID-Related Disease MIS-C

Jan. 8, 2021

Three studies highlight low COVID risk of in-person school | CIDRAP

RI Reports Six MIS-C Cases Connected To Coronavirus

4-year-old Central NY boy came down with rare Covid-related illness: ‘It’s beyond scary’

Michigan now releasing data on rare condition affecting some young children with COVID-19

“In October, Michigan was among only eight other states that would not disclose how many children died of COVID-19. MDHHS also did not confirm how many died of MIS-C.

But the state changed course over the holidays, releasing its first batch of data detailing MIS-C cases from the beginning of the pandemic through Dec. 14. Now, MIS-C data will be updated every first and third Thursday of the month, starting Jan. 7.“

Jan. 10, 2021

MIS-C cases among children in Sweden surge to 100, raising alarm about ICU bed shortage - Xinhua | English.news.cn

“STOCKHOLM, Jan. 10 (Xinhua) -- Around 100 children in Sweden have developed multisystem inflammatory syndrome (MIS-C) after contracting COVID-19, raising alarm about a shortage of intensive care unit (ICU) beds, local media reported Saturday.

Of the around 100 cases, 30 were linked to the second wave of the pandemic, causing doctors to be increasingly concerned, the newspaper Dagens Nyheter reported.“

Mother warns of ‘terrifying’ syndrome linked to COVID-19 that hospitalized 8-year-old son

Jan. 11, 2021

Syracuse boy, 9, recovers from rare COVID-related illness 'MIS-C'

Hazelhurst family says 4-year-old now cardiac patient after rare COVID side effect, MIS-C

Multisystem Inflammatory Syndrome in Children (MIS-C), a Post-viral Myocarditis and Systemic Vasculitis-A Critical Review of Its Pathogenesis and Treatment - Docwire News

Jan. 12, 2021


Michigan boy with rare COVID condition to require amputation


Rare COVID-linked illness MIS-C cause of Ventura County teens death

Attention to MIS-C Disease in Children with Covid-19

COVID-19 related infection in children on the rise

Long Beach reports first case of rare inflammatory disease linked to COVID-19 in children • Long Beach Post News

Family shares 5-year-old's battle with rare complication from COVID-19

Doctors warn of rare but dangerous condition linked to COVID-19 in children

Moeller student-athlete out of ICU after battling rare side effect of COVID-19

COVID-19 complications in children: Mother tells story of 5-year-old's severe inflammation

Jan. 13, 2021

Penn State Health: COVID-19 risks, symptoms different for children

“When it comes to children who are admitted to the hospital, only a small percentage of them have co-morbidity issues. Ericson said some children who have required respiratory support have some type of co-morbidity, including obesity, Down Syndrome or other significant lung problems.

However, the majority of children admitted to hospitals for acute care in Hershey have Multisystem inflammatory syndrome in children (MIS-C), which affects children who have no co-morbidity or other risk factors associated in adults with COVID-19.


According to the state Department of Health, MIS-C involves various body parts becoming inflamed, including the heart, lungs, kidneys, brain, skin, eyes or gastrointestinal organs. There are no known causes of MIS-C, though children with it either had the coronavirus or was around someone with COVID-19.“

Colorado health officials continue to warn of mysterious MIS-C syndrome seen in children


Children's Colorado seeing Rise in MIS-C cases in minorities - KRDO

Kids and COVID-19: More children hospitalized due coronavirus, MIS-C cases, possibility of vaccine required in schools | KGET 17

Baldwinsville boy, 11, recovers from rare COVID-related illness 'MIS-C'

LDH: Confirmed MIS-C cases continue to rise in Louisiana

Boy, 9, recovers from rare COVID-related illness 'MIS-C'

Alexander City teenager diagnosed with rare COVID-19 disorder

COVID complication lands 4-year-old in PICU - Central Wisconsin News

Coronavirus symptoms in children: How are COVID-19 symptoms different in children?

Jan. 14, 2021

15-year-old Simi Valley boy dies of MIS-C, rare illness linked to coronavirus


“MDH State Epidemiologist Dr. Ruth Lynfield also took time during the call to discuss MIS-C.

According to Lynfield, there have been 56 confirmed cases of MIS-C in Minnesota. No deaths have been reported in connection to the rare syndrome.

Lynfield said the average age for cases is 7.5, however, the range has been a range of cases in people from 6 months old to 20 years old.

A similar condition can occur in adults, however, Lynfield said that condition is even rarer.“ / source

Toddler in Arkansas battles aftermath of COVID-19; Doctors warn of MIS-C | KARK

Kentucky teen home after battle with MIS-C

Colorado Reports MIS-C Cases in Children | Pagosa Daily Post News Events & Video for Pagosa Springs Colorado

“In December 2020, Colorado hospitals reported the highest number of reported Multisystem Inflammatory Syndrome in Children (MIS-C) cases of any month since the COVID-19 pandemic began, which tracks with the rise in COVID-19 cases that occurred during October and November. Colorado currently has 29 cases of MIS-C that the Centers for Disease Control and Prevention (CDC) has confirmed, and we expect this number to grow as December cases continue to be reviewed — and compared alongside COVID-19 data. The state has had two MIS-C deaths, both reported in the spring of 2020.“

Jan. 15, 2021

COVID-19 cases increasing in children, teens

Covid-19: Boy left with red eyes, hands after contracting rare illness

Baystate Children’s Hospital treated 52 pediatric coronavirus cases; no deaths from COVID or related inflammatory disease

“The latest CDC data shows it has received 1,659 reports from 47 states of cases since mid-May, including more than 50 from Massachusetts meeting the definition for MIS-C. There were 26 deaths nationwide attributed to it.“

Frisco Mom Shares Warning After Son with Inflammatory Syndrome Tied to COVID-19 Misdiagnosed

“So though MIS-C is rare, she wants parents to know it is happening here and to be aware of the signs.

“You know your kids. Listen to them when they're saying they're not feeling well. If you've started some kind of treatment and they are not getting better, I would say within 24 hours, then you need to call and ask again. Advocate for your child,” said Borens.“

Jan. 16, 2021

9-Year-Old Girl Miraculously Survives Serious Illness Related to COVID-19


California:
“As of January 11, 167 cases of Multisystem Inflammatory Syndrome in Children (MIS-C) have been reported statewide. MIS-C is a rare inflammatory condition associated with COVID-19 that can damage multiple organ systems. MIS-C can require hospitalization and be life threatening.“ / source
 
Video:
Episode #22 - Children & COVID-19 - WHO | World Health Organization
22 January 2021 | Science conversation

“Summary
Are the symptoms of COVID-19 different in children? Do the new variants impact children differently? What can parents do to keep children safe from COVID-19. WHO's Dr Maria Van Kerkhove explains in Science in 5.

Science in 5 is WHO’s conversations in science. Watch WHO experts explain science related to COVID-19.”
 
December 29, 2020
(Via @sds71)

Children are more at risk of contracting coronavirus at a social gathering than in a classroom or childcare setting, according to a study released by the University of Mississippi Medical Center.

Study: Children get COVID-19 at gatherings more than at school | 10tv.com

Factors Associated with Positive SARS-CoV-2 Test Results in Outpatient Health Facilities and Emergency Departments Among Children and Adolescents Aged 18 Years — Mississippi, September–November 2020 | MMWR (cdc.gov)
 

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