margarita25
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Multisystem inflammatory syndrome in children (MIS-C and COVID-19)
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margarita25
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Michigan at 'record high' for COVID-19 hospitalizations of children | Bridge Michigan
“"The state is at a record high for hospitalizations for pediatrics during the entire pandemic and our hospital reflects that," said Dr. Rudolph Valentini, a pediatric nephrologist at Children's Hospital of Michigan and group chief medical officer for the Detroit Medical Center.“
[...]
“"As we're seeing more and more (COVID-19) cases in young people, we fear that we will see more cases of MIS-C at the Children's Hospital, so we're very prepared for that possibility," Olivero said.”
Of the children who develop MIS-C, 99% have tested positive for SARS CoV-2 or were in close contact with someone who had COVID-19, according to the CDC.
"As we're trying to combat this pandemic, this is one of the many, many very important consequences of COVID-19," Olivero said. "Children, they're not as able to communicate. They can't express themselves quite as well in terms of how they're feeling. It is kind of a scary thing to potentially come up against. And, of course, we know that children, especially our younger children, don't have any access to vaccines at this point in time."
Olivero said it's unknown what the long-term consequences of MIS-C are on the body, particularly on the heart. Children who develop the condition will need to be monitored by cardiologists throughout childhood and adolescence.
"We would think (it) is going to affect our children with chronic medical conditions more than our healthy children, but our young healthy children seem to be the ones who get MIS-C," Olivero said.“
“"The state is at a record high for hospitalizations for pediatrics during the entire pandemic and our hospital reflects that," said Dr. Rudolph Valentini, a pediatric nephrologist at Children's Hospital of Michigan and group chief medical officer for the Detroit Medical Center.“
[...]
“"As we're seeing more and more (COVID-19) cases in young people, we fear that we will see more cases of MIS-C at the Children's Hospital, so we're very prepared for that possibility," Olivero said.”
Of the children who develop MIS-C, 99% have tested positive for SARS CoV-2 or were in close contact with someone who had COVID-19, according to the CDC.
"As we're trying to combat this pandemic, this is one of the many, many very important consequences of COVID-19," Olivero said. "Children, they're not as able to communicate. They can't express themselves quite as well in terms of how they're feeling. It is kind of a scary thing to potentially come up against. And, of course, we know that children, especially our younger children, don't have any access to vaccines at this point in time."
Olivero said it's unknown what the long-term consequences of MIS-C are on the body, particularly on the heart. Children who develop the condition will need to be monitored by cardiologists throughout childhood and adolescence.
"We would think (it) is going to affect our children with chronic medical conditions more than our healthy children, but our young healthy children seem to be the ones who get MIS-C," Olivero said.“
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margarita25
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(Qmfr)
(*note - will need to pick up from Jan. 16, 2021)
ACR recommends 'stepwise approach' to immunomodulatory therapy in MIS-C linked to COVID-19
Dec. 21, 2020
More than 150 California children have been diagnosed with coronavirus-related syndrome
Dec. 23, 2020
Mancelona 4-Year-Old Returns Home After Days in Hospital with MIS-C, Parkinsonism - 9 & 10 News
““It attacked almost every single organ in his body, the rash was the skin, he has a little bit of brain damage of course,” says Day.
As well as Parkinsonism, making him the only known child in the world to get the disease from COVID.“
Dec. 24, 2020
Arkansas teen returns home after days battling MIS-C, a COVID-19 related illness in kids
Dec. 27, 2020
How inflammatory conditions, MIS-C and MIS-A, affect covid19 patients - Trinidad and Tobago Newsday
Dec. 28, 2020
Mother of Benton teen warns of inflammatory condition seen in children after COVID-19
Dec. 30, 2020
52 children in NC get inflammatory syndrome after COVID-19 infection
Mother of son fighting post-COVID illness urges parents to recognize MIS-C symptoms | wbir.com
“MIS-C, Abbott says, is way worse than the COVID that caused it.
“He did not have to be admitted to the hospital with COVID, where he coded here yesterday and ended up in the ICU” with MIS-C," she said.
Cook Children’s says there are four MIS-C patients in their hospital right now. At the same time, they report 18% of the children they’re testing for COVID are coming back positive; it’s a record no one wanted. “
Barron County family battles MIS-C after a mild experience with COVID-19
Dec. 31, 2020
4-year-old boy fights COVID-19 related inflammatory condition
Jan. 1, 2021
11-year-old fighting rare illness associated with COVID-19 in Texas hospital, mom says
'She would scream in pain': 7-year-old girl admitted to ICU for MIS-C after contracting coronavirus
Jan. 3, 2021
Alexandria teen on road to recovery after bout with life-threatening COVID-related illness
Jan. 4, 2021
Doctors seeing an increase in MIS-C in children | cbs8.com
Five children fight MIS-C at Texas hospital; mom tells parents to | khou.com
"”They told me here the sooner they get the kids, the less harm it will do to their bodies," Copeland said.”
Jan. 5, 2021
Flemingsburg mother warns of COVID MIS-C syndrome after 6-year-old son spent more than a week in ICU
MIS-C, a rare condition tied to COVID-19, affects southern Indiana boy
Jan. 6, 2021
Abilene boy Cason Abbott out of hospital after battle with MIS-C
Michigan health department starting to report cases of MIS-C with children
https://www.scribd.com/document/489940175/MIS-C-Fast-Fact-Sheet-121520-711597-7
“As of December 14, 2020, there have been 43 cases of MIS-C reported in Michigan.
Of the 43 reported cases, there have been less than six deaths and 30 of the cases have been admitted to the Intensive Care Unit.
According to the Centers for Disease Control and Prevention, 47 states in the U.S. have reported at least one case of MIS-C.“
Jan. 7, 2021
Doctors alarmed at mystery illness in children with links to COVID-19
MUSC Children's Hospital using new method to treat MIS-C
“MUSC’s Shawn Jenkins Children’s Hospital has seen 14 children with MIS-C within the last year. The hospital is the first in the nation to try a new treatment for those with severe cases. The treatment is called remestemcel-L, currently in clinical trials as part of an expanded access program. The therapy uses mesenchymal stromal cells, which is made in the bone marrow of healthy people.“
Exclusive: Long Island Father Talks About Young Son's Bout With Rare COVID-Related Disease MIS-C
Jan. 8, 2021
Three studies highlight low COVID risk of in-person school | CIDRAP
RI Reports Six MIS-C Cases Connected To Coronavirus
4-year-old Central NY boy came down with rare Covid-related illness: ‘It’s beyond scary’
Michigan now releasing data on rare condition affecting some young children with COVID-19
“In October, Michigan was among only eight other states that would not disclose how many children died of COVID-19. MDHHS also did not confirm how many died of MIS-C.
But the state changed course over the holidays, releasing its first batch of data detailing MIS-C cases from the beginning of the pandemic through Dec. 14. Now, MIS-C data will be updated every first and third Thursday of the month, starting Jan. 7.“
Jan. 10, 2021
MIS-C cases among children in Sweden surge to 100, raising alarm about ICU bed shortage - Xinhua | English.news.cn
“STOCKHOLM, Jan. 10 (Xinhua) -- Around 100 children in Sweden have developed multisystem inflammatory syndrome (MIS-C) after contracting COVID-19, raising alarm about a shortage of intensive care unit (ICU) beds, local media reported Saturday.
Of the around 100 cases, 30 were linked to the second wave of the pandemic, causing doctors to be increasingly concerned, the newspaper Dagens Nyheter reported.“
Mother warns of ‘terrifying’ syndrome linked to COVID-19 that hospitalized 8-year-old son
Jan. 11, 2021
Syracuse boy, 9, recovers from rare COVID-related illness 'MIS-C'
Hazelhurst family says 4-year-old now cardiac patient after rare COVID side effect, MIS-C
Multisystem Inflammatory Syndrome in Children (MIS-C), a Post-viral Myocarditis and Systemic Vasculitis-A Critical Review of Its Pathogenesis and Treatment - Docwire News
Jan. 12, 2021
Michigan boy with rare COVID condition to require amputation
Rare COVID-linked illness MIS-C cause of Ventura County teens death
Attention to MIS-C Disease in Children with Covid-19
COVID-19 related infection in children on the rise
Long Beach reports first case of rare inflammatory disease linked to COVID-19 in children • Long Beach Post News
Family shares 5-year-old's battle with rare complication from COVID-19
Doctors warn of rare but dangerous condition linked to COVID-19 in children
Moeller student-athlete out of ICU after battling rare side effect of COVID-19
COVID-19 complications in children: Mother tells story of 5-year-old's severe inflammation
Jan. 13, 2021
Penn State Health: COVID-19 risks, symptoms different for children
“When it comes to children who are admitted to the hospital, only a small percentage of them have co-morbidity issues. Ericson said some children who have required respiratory support have some type of co-morbidity, including obesity, Down Syndrome or other significant lung problems.
However, the majority of children admitted to hospitals for acute care in Hershey have Multisystem inflammatory syndrome in children (MIS-C), which affects children who have no co-morbidity or other risk factors associated in adults with COVID-19.
According to the state Department of Health, MIS-C involves various body parts becoming inflamed, including the heart, lungs, kidneys, brain, skin, eyes or gastrointestinal organs. There are no known causes of MIS-C, though children with it either had the coronavirus or was around someone with COVID-19.“
Colorado health officials continue to warn of mysterious MIS-C syndrome seen in children
Children's Colorado seeing Rise in MIS-C cases in minorities - KRDO
Kids and COVID-19: More children hospitalized due coronavirus, MIS-C cases, possibility of vaccine required in schools | KGET 17
Baldwinsville boy, 11, recovers from rare COVID-related illness 'MIS-C'
LDH: Confirmed MIS-C cases continue to rise in Louisiana
Boy, 9, recovers from rare COVID-related illness 'MIS-C'
Alexander City teenager diagnosed with rare COVID-19 disorder
COVID complication lands 4-year-old in PICU - Central Wisconsin News
Coronavirus symptoms in children: How are COVID-19 symptoms different in children?
Jan. 14, 2021
15-year-old Simi Valley boy dies of MIS-C, rare illness linked to coronavirus
“MDH State Epidemiologist Dr. Ruth Lynfield also took time during the call to discuss MIS-C.
According to Lynfield, there have been 56 confirmed cases of MIS-C in Minnesota. No deaths have been reported in connection to the rare syndrome.
Lynfield said the average age for cases is 7.5, however, the range has been a range of cases in people from 6 months old to 20 years old.
A similar condition can occur in adults, however, Lynfield said that condition is even rarer.“ / source
Toddler in Arkansas battles aftermath of COVID-19; Doctors warn of MIS-C | KARK
Kentucky teen home after battle with MIS-C
Colorado Reports MIS-C Cases in Children | Pagosa Daily Post News Events & Video for Pagosa Springs Colorado
“In December 2020, Colorado hospitals reported the highest number of reported Multisystem Inflammatory Syndrome in Children (MIS-C) cases of any month since the COVID-19 pandemic began, which tracks with the rise in COVID-19 cases that occurred during October and November. Colorado currently has 29 cases of MIS-C that the Centers for Disease Control and Prevention (CDC) has confirmed, and we expect this number to grow as December cases continue to be reviewed — and compared alongside COVID-19 data. The state has had two MIS-C deaths, both reported in the spring of 2020.“
Jan. 15, 2021
COVID-19 cases increasing in children, teens
Covid-19: Boy left with red eyes, hands after contracting rare illness
Baystate Children’s Hospital treated 52 pediatric coronavirus cases; no deaths from COVID or related inflammatory disease
“The latest CDC data shows it has received 1,659 reports from 47 states of cases since mid-May, including more than 50 from Massachusetts meeting the definition for MIS-C. There were 26 deaths nationwide attributed to it.“
Frisco Mom Shares Warning After Son with Inflammatory Syndrome Tied to COVID-19 Misdiagnosed
“So though MIS-C is rare, she wants parents to know it is happening here and to be aware of the signs.
“You know your kids. Listen to them when they're saying they're not feeling well. If you've started some kind of treatment and they are not getting better, I would say within 24 hours, then you need to call and ask again. Advocate for your child,” said Borens.“
Jan. 16, 2021
9-Year-Old Girl Miraculously Survives Serious Illness Related to COVID-19
California:
“As of January 11, 167 cases of Multisystem Inflammatory Syndrome in Children (MIS-C) have been reported statewide. MIS-C is a rare inflammatory condition associated with COVID-19 that can damage multiple organ systems. MIS-C can require hospitalization and be life threatening.“ / source
(*note - will need to pick up from Jan. 16, 2021)
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margarita25
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Researchers hunt for cause of rare, COVID-19–linked immune disease in children
March 18, 2021
“The immunologic findings dovetail with what doctors have seen: Most children with MIS-C improve rapidly with therapies that suppress the immune system. U.S. MIS-C patients are routinely treated with intravenous immunoglobulin. But this treatment often isn’t available in underresourced countries. In September 2020, a large U.K. clinical trial called Recovery, which has been testing therapies on thousands of adults, began to recruit children for a study of other approaches. “Across the globe, people have adopted different strategies” for treating MIS-C, says Elizabeth Whittaker, a pediatric infectious disease specialist at Imperial College London, who’s involved in the trial. Trial leaders want to know whether children can be treated with steroids alone or even just supportive care, for example drugs to stabilize blood pressure.
Ironically, powerful treatments for MIS-C also make it harder to study: Blood samples to probe the immune system are often collected after therapy has started. Treatment “changes a tremendous number of cell types,” says Virginia Pascual, a pediatric rheumatologist and director of the Gale and Ira Drukier Institute for Children’s Health at Weill Cornell Medicine. Her work is part of a large study called the Pediatric Research Immune Network on SARS-CoV-2 and MIS-C (PRISM), which aims to decipher the causes and long-term outcomes of the syndrome.“
*more at link
March 18, 2021
“The immunologic findings dovetail with what doctors have seen: Most children with MIS-C improve rapidly with therapies that suppress the immune system. U.S. MIS-C patients are routinely treated with intravenous immunoglobulin. But this treatment often isn’t available in underresourced countries. In September 2020, a large U.K. clinical trial called Recovery, which has been testing therapies on thousands of adults, began to recruit children for a study of other approaches. “Across the globe, people have adopted different strategies” for treating MIS-C, says Elizabeth Whittaker, a pediatric infectious disease specialist at Imperial College London, who’s involved in the trial. Trial leaders want to know whether children can be treated with steroids alone or even just supportive care, for example drugs to stabilize blood pressure.
Ironically, powerful treatments for MIS-C also make it harder to study: Blood samples to probe the immune system are often collected after therapy has started. Treatment “changes a tremendous number of cell types,” says Virginia Pascual, a pediatric rheumatologist and director of the Gale and Ira Drukier Institute for Children’s Health at Weill Cornell Medicine. Her work is part of a large study called the Pediatric Research Immune Network on SARS-CoV-2 and MIS-C (PRISM), which aims to decipher the causes and long-term outcomes of the syndrome.“
*more at link
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margarita25
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Syndrome Temporally associated with SARS-CoV-2 (PIMS-TS) in Children
Press Release Title: Half of Kids with Inflammatory Syndrome After COVID-19 Have Neurologic Symptoms
April 13, 2021
AAN Abstract - Neurologic and radiographic findings associated with Pediatric Inflammatory Multisystem Syndrome... - Abdel-Mannan titled.pdf
“Conclusions: Children with PIMS-TS presented with new neurological symptoms involving both the central and peripheral nervous systems, in the absence of respiratory symptoms. Neurological symptoms were seen more frequently in more severe presentations.“
—
Some Children With Covid-Related Syndrome Develop Neurological Symptoms
—
“Unfortunately, MIS-C may lead to neurological problems as well. A new study from the American Academy of Neurology found that of the 46 patients they studied last year at the Great Ormond Street Hospital in England - who were 65 percent male with a median age of 10.2 years old - 24 of them "presented with new neurological symptoms involving both the central and peripheral nervous systems, in the absence of respiratory symptoms." Specifically, these patients experienced symptoms they never had before, like headaches, hallucinations, seizures, confusion, speech impairments, and problems with balance and coordination, according to The New York Times. These neurological issues typically subside with proper medical treatment.“
What Parents Need to Know About Multisystem Inflammatory Syndrome, an Illness Related to COVID-19
April 15, 2021
Press Release Title: Half of Kids with Inflammatory Syndrome After COVID-19 Have Neurologic Symptoms
April 13, 2021
AAN Abstract - Neurologic and radiographic findings associated with Pediatric Inflammatory Multisystem Syndrome... - Abdel-Mannan titled.pdf
“Conclusions: Children with PIMS-TS presented with new neurological symptoms involving both the central and peripheral nervous systems, in the absence of respiratory symptoms. Neurological symptoms were seen more frequently in more severe presentations.“
—
Some Children With Covid-Related Syndrome Develop Neurological Symptoms
—
“Unfortunately, MIS-C may lead to neurological problems as well. A new study from the American Academy of Neurology found that of the 46 patients they studied last year at the Great Ormond Street Hospital in England - who were 65 percent male with a median age of 10.2 years old - 24 of them "presented with new neurological symptoms involving both the central and peripheral nervous systems, in the absence of respiratory symptoms." Specifically, these patients experienced symptoms they never had before, like headaches, hallucinations, seizures, confusion, speech impairments, and problems with balance and coordination, according to The New York Times. These neurological issues typically subside with proper medical treatment.“
What Parents Need to Know About Multisystem Inflammatory Syndrome, an Illness Related to COVID-19
April 15, 2021
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margarita25
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March 18, 2021
These children had covid-19. Now, they have long-haul symptoms.
https://www.washingtonpost.com/health/2021/03/18/virus-longhaul-coronavirus-children/
“A growing number of medical centers — Boston Children’s Hospital, Kennedy Krieger Institute in Baltimore, National Jewish Health in Denver and Norton Children’s Hospital in Louisville — are setting up multidisciplinary clinics to try to better understand and treat these patients. And a research project funded by the National Institutes of Health that is getting underway will explore the range of impacts covid-19 has had on children.
“One of the most difficult things about caring for these patients is they have a lot of questions about short- and long-term effects, about what to expect,” said Dongngan Truong, a pediatric cardiologist at Intermountain Primary Children’s Hospital in Salt Lake City, where Madilyn is being treated. “And right now, we don’t know what to expect.”“
March 22, 2021
MIS-C: Doctors fighting back on rare COVID-19 complication in kids
“Patients will visit the Riley Clinic two weeks after discharge. They'll come back for six-week, six-month and one-year check-ins. At each clinic visit, patients undergo tests to check their heart function and see a cardiologist, rheumatologist and infectious disease specialist.
“It may be overkill right now to follow them that far out but we’re still learning about after-effects,” said Dr. Samina Bhumbra, pediatric infectious disease specialist at Riley’s Ryan White Center for Pediatric Infectious Disease and Global Health.”
[...]
“Doctors can’t answer why some people develop this but most do not. They do know MIS-C appears slightly more often in boys. More than two-thirds of those who have been diagnosed have been Latino or Black children. Most children who fall ill are between 1 and 14 years old.
Unlike with an acute COVID-19 infection, the lungs do not tend to be as involved when a child develops MIS-C, Bhumbra said. Instead, because this is an inflammatory disease, the heart tends to be more involved.“
Note*
“At first the doctors thought Richard Barnes had appendicitis.“
March 27, 2021
8 Alaska youths experienced a rare and serious inflammatory syndrome after COVID-19 infections
April 2, 2021
CMU College of Medicine Professors Lead Research into MIS-C in Children - 9 & 10 News
“Now, some professors at Central Michigan University are seeing if saliva could hold the key to preventing severe MIS-C infections.“
[...]
The study is one of just eight fully funded by the National Institutes for Health, looking at ways to quickly identify children at risk for MIS-C.”
April 7, 2021
Most Children Who Developed MIS-C Initially Had Few Signs Of Covid
The study of children who developed the serious inflammatory illness included almost 1,800 cases reported to the CDC from March 2020 through mid-January.
April 12, 2021
COVID-19 cases rising in children, health officials warn of more hospitalizations, MIS-C
Rare COVID-19 complication is putting kids in Michigan's ICUs
April 14, 2021
ADHS: 3 deaths linked to COVID-related condition in kids called MIS-C
“The Arizona Department of Health Services told ABC15 there have been 116 confirmed MIS-C cases in Arizona.
"Every time we had a surge of COVID-19 cases, that surge of COVID-19 cases was followed by a surge of MIS-C cases," said Dr. Wassim Ballan, a pediatric infectious diseases specialist at Phoenix Children's Hospital.“
Massachusetts:
Mass. releases more data on COVID infections among children as overall active cases decline for second straight day
“The Department of Public Health on Wednesday released new data showing the number of infections confirmed among children younger than 15. Over the last two weeks, 1,235 cases were confirmed in children younger than four; 1,469 infections were confirmed in children between the ages of 5 and 9; and 1,816 infections were confirmed in children between the ages of 10 and 14, according to the latest data from the Department of Public Health.
There were 2,696 teenagers between the ages of 15 and 19 who came down with COVID over the last two weeks. And 5,942 cases were confirmed among 20-somethings, according to DPH.”
What you need to know about MIS-C, the post-COVID sickness affecting kids
“Doctors at Cincinnati Children’s Hospital say they’re worried a potential spring wave of COVID-19 could bring an accompanying uptick in cases of MIS-C — and, with every case, potential that another child will have fatal complications.
“The worry is that if we are about to experience a fourth wave of COVID, fueled in part by some of these new variants, whether we're going to start seeing increasing numbers over the next couple of weeks,” said Dr. Grant Schulert, who works at Children’s.“
“I didn’t think it was that big of a deal, until my son’s life was plugged into the wall.” Muskegon mother recounts child's battle with MIS-C
April 15, 2021
Mesa mother warns other parents about impact of MIS-C in children
"”With her, it affected her GI system. All of her intestines were inflamed," her mother said.“
[...]
“Raelynn progressively got worse.
"Air in her portal vein to her liver along with two blood clots. There was a surgery that was going to be on board as well. They were going to have to remove her entire colon because that’s how severe it was," Milliman said.
Thankfully because of other treatments, Raelynn didn't have to have that surgery.”
—
Milford Boy, 5, Battles COVID-19, And Rare Inflammatory Condition
“All told there have been 25-49 cases of MIS-C in Connecticut, according to the CDC. In the United States there have been 3,185 cases and 36 reported deaths.“
These children had covid-19. Now, they have long-haul symptoms.
https://www.washingtonpost.com/health/2021/03/18/virus-longhaul-coronavirus-children/
“A growing number of medical centers — Boston Children’s Hospital, Kennedy Krieger Institute in Baltimore, National Jewish Health in Denver and Norton Children’s Hospital in Louisville — are setting up multidisciplinary clinics to try to better understand and treat these patients. And a research project funded by the National Institutes of Health that is getting underway will explore the range of impacts covid-19 has had on children.
“One of the most difficult things about caring for these patients is they have a lot of questions about short- and long-term effects, about what to expect,” said Dongngan Truong, a pediatric cardiologist at Intermountain Primary Children’s Hospital in Salt Lake City, where Madilyn is being treated. “And right now, we don’t know what to expect.”“
March 22, 2021
MIS-C: Doctors fighting back on rare COVID-19 complication in kids
“Patients will visit the Riley Clinic two weeks after discharge. They'll come back for six-week, six-month and one-year check-ins. At each clinic visit, patients undergo tests to check their heart function and see a cardiologist, rheumatologist and infectious disease specialist.
“It may be overkill right now to follow them that far out but we’re still learning about after-effects,” said Dr. Samina Bhumbra, pediatric infectious disease specialist at Riley’s Ryan White Center for Pediatric Infectious Disease and Global Health.”
[...]
“Doctors can’t answer why some people develop this but most do not. They do know MIS-C appears slightly more often in boys. More than two-thirds of those who have been diagnosed have been Latino or Black children. Most children who fall ill are between 1 and 14 years old.
Unlike with an acute COVID-19 infection, the lungs do not tend to be as involved when a child develops MIS-C, Bhumbra said. Instead, because this is an inflammatory disease, the heart tends to be more involved.“
Note*
“At first the doctors thought Richard Barnes had appendicitis.“
March 27, 2021
8 Alaska youths experienced a rare and serious inflammatory syndrome after COVID-19 infections
April 2, 2021
CMU College of Medicine Professors Lead Research into MIS-C in Children - 9 & 10 News
“Now, some professors at Central Michigan University are seeing if saliva could hold the key to preventing severe MIS-C infections.“
[...]
The study is one of just eight fully funded by the National Institutes for Health, looking at ways to quickly identify children at risk for MIS-C.”
April 7, 2021
Most Children Who Developed MIS-C Initially Had Few Signs Of Covid
The study of children who developed the serious inflammatory illness included almost 1,800 cases reported to the CDC from March 2020 through mid-January.
April 12, 2021
COVID-19 cases rising in children, health officials warn of more hospitalizations, MIS-C
Rare COVID-19 complication is putting kids in Michigan's ICUs
April 14, 2021
ADHS: 3 deaths linked to COVID-related condition in kids called MIS-C
“The Arizona Department of Health Services told ABC15 there have been 116 confirmed MIS-C cases in Arizona.
"Every time we had a surge of COVID-19 cases, that surge of COVID-19 cases was followed by a surge of MIS-C cases," said Dr. Wassim Ballan, a pediatric infectious diseases specialist at Phoenix Children's Hospital.“
Massachusetts:
Mass. releases more data on COVID infections among children as overall active cases decline for second straight day
“The Department of Public Health on Wednesday released new data showing the number of infections confirmed among children younger than 15. Over the last two weeks, 1,235 cases were confirmed in children younger than four; 1,469 infections were confirmed in children between the ages of 5 and 9; and 1,816 infections were confirmed in children between the ages of 10 and 14, according to the latest data from the Department of Public Health.
There were 2,696 teenagers between the ages of 15 and 19 who came down with COVID over the last two weeks. And 5,942 cases were confirmed among 20-somethings, according to DPH.”
What you need to know about MIS-C, the post-COVID sickness affecting kids
“Doctors at Cincinnati Children’s Hospital say they’re worried a potential spring wave of COVID-19 could bring an accompanying uptick in cases of MIS-C — and, with every case, potential that another child will have fatal complications.
“The worry is that if we are about to experience a fourth wave of COVID, fueled in part by some of these new variants, whether we're going to start seeing increasing numbers over the next couple of weeks,” said Dr. Grant Schulert, who works at Children’s.“
“I didn’t think it was that big of a deal, until my son’s life was plugged into the wall.” Muskegon mother recounts child's battle with MIS-C
April 15, 2021
Mesa mother warns other parents about impact of MIS-C in children
"”With her, it affected her GI system. All of her intestines were inflamed," her mother said.“
[...]
“Raelynn progressively got worse.
"Air in her portal vein to her liver along with two blood clots. There was a surgery that was going to be on board as well. They were going to have to remove her entire colon because that’s how severe it was," Milliman said.
Thankfully because of other treatments, Raelynn didn't have to have that surgery.”
—
Milford Boy, 5, Battles COVID-19, And Rare Inflammatory Condition
“All told there have been 25-49 cases of MIS-C in Connecticut, according to the CDC. In the United States there have been 3,185 cases and 36 reported deaths.“
Last edited:
margarita25
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Stanford begins testing Pfizer COVID-19 vaccine on children as young as 2
“As statewide eligibility for the COVID-19 vaccine expands to residents 16 and older in California, researchers at Stanford Medicine have set their sights on an even younger group: children ages 2 to 5.
The medical school Wednesday began administering doses to children in the tender age group as part of a larger, three-phase trial of Pfizer-BioNech’s COVID-19 vaccine that will ultimately include children ages 6 months to 12 years.
“We want to protect children just as we want to protect adults from this disease,” said Dr. Yvonne Maldonado, the pediatric infectious diseases expert leading the trial at Stanford. “The goal is to have a pediatric vaccine available for all age groups from 6 months of age to adulthood.”“
“As statewide eligibility for the COVID-19 vaccine expands to residents 16 and older in California, researchers at Stanford Medicine have set their sights on an even younger group: children ages 2 to 5.
The medical school Wednesday began administering doses to children in the tender age group as part of a larger, three-phase trial of Pfizer-BioNech’s COVID-19 vaccine that will ultimately include children ages 6 months to 12 years.
“We want to protect children just as we want to protect adults from this disease,” said Dr. Yvonne Maldonado, the pediatric infectious diseases expert leading the trial at Stanford. “The goal is to have a pediatric vaccine available for all age groups from 6 months of age to adulthood.”“
margarita25
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Unusually high Covid-19 deaths among babies, young children in Brazil. Here’s why
“Brazil has been one of the worst-hit nations by the coronavirus disease (Covid-19) pandemic but the unusual high deaths among babies have caused immense concerns. Despite overwhelming evidence based on data that Covid-19 rarely turns fatal for children, around 1,300 babies have died from coronavirus, according to a BBC report.“
[...]
BBM:
“According to experts quoted by BBC, Brazil’s sheer number of Covid-19 cases have led to an increase in infection among babies and young children. While Brazil’s official data suggest that Covid-19 killed at least 852 children up to the age of nine, Dr Fatima Marinho, a leading epidemiologist from the University of São Paolo, did research that estimated the virus killed 2,060 children under nine years old, including 1,302 babies. Marinho told BBC that she is seeing more cases of MIS-C than ever before, highlighting that there is a misconception that children are at a zero risk for Covid-19.“
margarita25
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Why are so many babies dying of Covid-19 in Brazil?
“Dr Monte, who treated Lucas, agrees. She says that although MIS cannot be prevented, treatment is much more successful if the condition is diagnosed and treated early.
"The earlier he would have received specialised care, the better," she says. "He arrived at the hospital already critically ill. I believe he could have had a different outcome if we could have treated him earlier."
Jessika now wants to share Lucas's story to help others who may miss critical symptoms.“
[...]
“There is a misconception that children are at zero risk for Covid, says Dr Fatima Marinho, who is also a senior adviser to the international health NGO Vital Strategies. Marinho's research has found that a shockingly high number of children and babies have been affected by the virus.
Between February 2020 and 15 March 2021, Covid-19 killed at least 852 of Brazil's children up to the age of nine, including 518 babies under one year old, according to figures from the Brazilian Ministry of Health. But Dr Marinho estimates that more than twice this number of children died of Covid. A serious problem of underreporting due to lack of Covid testing is bringing the numbers down, she says.
Dr Marinho calculated the excess of deaths by unspecified acute respiratory syndrome during the pandemic, and found that there were 10 times more deaths by unexplained respiratory syndrome than in previous years. By adding these numbers, she estimates that the virus in fact killed 2,060 children under nine years old, including 1,302 babies.“
[...]
“"It hurts to see a child dying without seeing their parents," says Dr Carneiro.“
“Dr Monte, who treated Lucas, agrees. She says that although MIS cannot be prevented, treatment is much more successful if the condition is diagnosed and treated early.
"The earlier he would have received specialised care, the better," she says. "He arrived at the hospital already critically ill. I believe he could have had a different outcome if we could have treated him earlier."
Jessika now wants to share Lucas's story to help others who may miss critical symptoms.“
[...]
“There is a misconception that children are at zero risk for Covid, says Dr Fatima Marinho, who is also a senior adviser to the international health NGO Vital Strategies. Marinho's research has found that a shockingly high number of children and babies have been affected by the virus.
Between February 2020 and 15 March 2021, Covid-19 killed at least 852 of Brazil's children up to the age of nine, including 518 babies under one year old, according to figures from the Brazilian Ministry of Health. But Dr Marinho estimates that more than twice this number of children died of Covid. A serious problem of underreporting due to lack of Covid testing is bringing the numbers down, she says.
Dr Marinho calculated the excess of deaths by unspecified acute respiratory syndrome during the pandemic, and found that there were 10 times more deaths by unexplained respiratory syndrome than in previous years. By adding these numbers, she estimates that the virus in fact killed 2,060 children under nine years old, including 1,302 babies.“
[...]
“"It hurts to see a child dying without seeing their parents," says Dr Carneiro.“
sds71
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“Saturday morning, he woke up, he had red cracked lips, his tongue was white with red spots on it,” Kendall said.
That’s when they took him to Yale New Haven Hospital.
“He didn’t have the main symptom you’re told to look out for so that’s why we just kind of want to spread awareness, because even if it doesn’t look like the exact symptoms you’re supposed to be looking for, he had several of the other symptoms,” she said.
He had a fever for several days that his doctor thought may be a virus. He had stomach pain but no rash that’s often seen with MIS-C.
Salazar said 144 children have been treated for COVID-19 at their hospital during the pandemic.
“We have seen in the last three to four weeks an increase once again of kids coming in diagnosed with COVID-19,” Salazar said.
Doctors say there may be a genetic pre-disposition to MIS-C. Jace is taking part in a research study.
Pediatric COVID-19 Complications Still a Concern for Parents, Doctors
That’s when they took him to Yale New Haven Hospital.
“He didn’t have the main symptom you’re told to look out for so that’s why we just kind of want to spread awareness, because even if it doesn’t look like the exact symptoms you’re supposed to be looking for, he had several of the other symptoms,” she said.
He had a fever for several days that his doctor thought may be a virus. He had stomach pain but no rash that’s often seen with MIS-C.
Salazar said 144 children have been treated for COVID-19 at their hospital during the pandemic.
“We have seen in the last three to four weeks an increase once again of kids coming in diagnosed with COVID-19,” Salazar said.
Doctors say there may be a genetic pre-disposition to MIS-C. Jace is taking part in a research study.
Pediatric COVID-19 Complications Still a Concern for Parents, Doctors
margarita25
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India / Children / Alarming Rise In Pediatric Cases
margarita25
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Colorado is seeing a rapid increase in COVID cases among children, health officials say
April 27, 2021
“DENVER — While the state’s overall case rates of COVID-19 have stabilized somewhat over the last month, Colorado is seeing a jump in cases among middle school and high school aged children, State Epidemiologist Dr. Rachel Herlihy said Tuesday.
Dr. Herlihy said the state is also seeing an upward trend in cases among children 3-10 years old, but cases among children 11-17 years old has shot up dramatically. Herlihy did not offer an explanation as to why those age groups are seeing an increase in cases.”
—
India Blames a Virus Variant as Its Covid-19 Crisis Deepens
““The current wave of Covid has a different clinical behavior,” said Dr. Sujay Shad, a senior cardiac surgeon at Sir Ganga Ram Hospital, where two of the doctors needed supplemental oxygen to recover. “It’s affecting young adults. It’s affecting families. It’s a new thing altogether. Two-month-old babies are getting infected.””
April 27, 2021
“DENVER — While the state’s overall case rates of COVID-19 have stabilized somewhat over the last month, Colorado is seeing a jump in cases among middle school and high school aged children, State Epidemiologist Dr. Rachel Herlihy said Tuesday.
Dr. Herlihy said the state is also seeing an upward trend in cases among children 3-10 years old, but cases among children 11-17 years old has shot up dramatically. Herlihy did not offer an explanation as to why those age groups are seeing an increase in cases.”
—
India Blames a Virus Variant as Its Covid-19 Crisis Deepens
““The current wave of Covid has a different clinical behavior,” said Dr. Sujay Shad, a senior cardiac surgeon at Sir Ganga Ram Hospital, where two of the doctors needed supplemental oxygen to recover. “It’s affecting young adults. It’s affecting families. It’s a new thing altogether. Two-month-old babies are getting infected.””
Last edited:
sds71
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The most severe symptoms that come with MIS-C, the rare but serious Covid-19 related condition, seem to resolve within six months after hospitalization, according to a new small study of patients at one hospital in London.
Most severe effects of MIS-C in children typically resolve within six months, new research suggests | News | wfsb.com
6-month multidisciplinary follow-up and outcomes of patients with paediatric inflammatory multisystem syndrome (PIMS-TS) at a UK tertiary paediatric hospital: a retrospective cohort study - The Lancet Child & Adolescent Health
Most severe effects of MIS-C in children typically resolve within six months, new research suggests | News | wfsb.com
6-month multidisciplinary follow-up and outcomes of patients with paediatric inflammatory multisystem syndrome (PIMS-TS) at a UK tertiary paediatric hospital: a retrospective cohort study - The Lancet Child & Adolescent Health
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Incidence of Multisystem Inflammatory Syndrome in Children Among US Persons Infected With SARS-CoV-2
June 10, 2021
Incidence of Multisystem Inflammatory Syndrome in Children Among US Persons Infected With SARS-CoV-2
Amanda B. Payne, PhD, MPH1, et al.
JAMA Netw Open. 2021;4(6):e2116420. doi:10.1001/jamanetworkopen.2021.16420
Key Points
Question What was the incidence of multisystem inflammatory syndrome in children (MIS-C) among persons with SARS-CoV-2 infection in the US during April to June 2020?
Findings In this cohort study of 248 persons with MIS-C, MIS-C incidence was 5.1 persons per 1 000 000 person-months and 316 persons per 1 000 000 SARS-CoV-2 infections in persons younger than 21 years. Incidence was higher among Black, Hispanic or Latino, and Asian or Pacific Islander persons compared with White persons and in younger persons compared with older persons.
Meaning These findings suggest that MIS-C was a rare complication of SARS-CoV-2 infection; further study is needed to understand why MIS-C incidence varied by race/ethnicity and age group.
June 10, 2021
Incidence of Multisystem Inflammatory Syndrome in Children Among US Persons Infected With SARS-CoV-2
Amanda B. Payne, PhD, MPH1, et al.
JAMA Netw Open. 2021;4(6):e2116420. doi:10.1001/jamanetworkopen.2021.16420
Key Points
Question What was the incidence of multisystem inflammatory syndrome in children (MIS-C) among persons with SARS-CoV-2 infection in the US during April to June 2020?
Findings In this cohort study of 248 persons with MIS-C, MIS-C incidence was 5.1 persons per 1 000 000 person-months and 316 persons per 1 000 000 SARS-CoV-2 infections in persons younger than 21 years. Incidence was higher among Black, Hispanic or Latino, and Asian or Pacific Islander persons compared with White persons and in younger persons compared with older persons.
Meaning These findings suggest that MIS-C was a rare complication of SARS-CoV-2 infection; further study is needed to understand why MIS-C incidence varied by race/ethnicity and age group.
margarita25
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[URL="https://www.tennessean.com/story/news/local/coronavirus/2021/08/06/covid-19-cases-hospitalizations-children-tennessee/5512310001/"]Tennessee reported more COVID-19 cases in children as schools resume
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On Tuesday, the state's health chief, Dr. Lisa Piercey, said the delta variant is spreading quickly in children, who also tend to show symptoms shortly after exposure. This is significant because it could indicate a much faster incubation time than previous versions of the coronavirus.
The department also projected children's hospitals in Tennessee will be completely full by the end of next week.
Two children died at Le Bonheur Children's Hospital in Memphis over the weekend. An 11-year-old in West Memphis died on Monday from COVID-19, as reported by The Commercial Appeal.
[/URL]
On Tuesday, the state's health chief, Dr. Lisa Piercey, said the delta variant is spreading quickly in children, who also tend to show symptoms shortly after exposure. This is significant because it could indicate a much faster incubation time than previous versions of the coronavirus.
The department also projected children's hospitals in Tennessee will be completely full by the end of next week.
Two children died at Le Bonheur Children's Hospital in Memphis over the weekend. An 11-year-old in West Memphis died on Monday from COVID-19, as reported by The Commercial Appeal.
anneg
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An article from July 29:
Hospitals In Southern U.S. Report Record Numbers Of Children Hospitalized Amid Delta Surge—Though Deaths Still Extremely Rare
While it is still extremely rare for children to become seriously ill or die from Covid-19, hospitals primarily based in the southern U.S. are reporting a sharp uptick in the number of children they are seeing admitted.
[...]
Major children’s hospitals in Alabama, Arkansas, Louisiana and Florida—states that have been battling a broader increase in hospitalizations—all said this week they have more children in their care than at any other point in the pandemic.
Coronavirus-linked hospitalizations are up 50% from their previous peak at the Arkansas Children’s hospitals in Little Rock and Springdale, the hospitals’ chief clinical officer told CNN, deeming the 24 total pediatric patients housed at their facilities as of Wednesday (which includes seven in intensive care and two on ventilators) the “worst we’ve ever seen it for kids.”
Louisiana has also seen child hospitalizations surge in multiple cities, with the number of patients at Children’s Hospital New Orleans jumping from six at the start of the week to a record 17 on Thursday morning; the facility has paused surgeries to redeploy staff to critical care units.
[...]
In Florida, the trend has been reported in Palm Beach, St. Petersburg, and in Jacksonville, where a top pediatric infectious disease specialist counted a record 20 children currently hospitalized across the city.
[...]
Alabama has hit a new peak state-wide, according to Alabama Hospital Association President Don Williamson, who told The Alabama Reporter that the 32 children currently hospitalized with Covid-19 outpaces the numbers seen even when the state was at its peak in terms of hospitalizations in January.
Hospitals In Southern U.S. Report Record Numbers Of Children Hospitalized Amid Delta Surge—Though Deaths Still Extremely Rare
While it is still extremely rare for children to become seriously ill or die from Covid-19, hospitals primarily based in the southern U.S. are reporting a sharp uptick in the number of children they are seeing admitted.
[...]
Major children’s hospitals in Alabama, Arkansas, Louisiana and Florida—states that have been battling a broader increase in hospitalizations—all said this week they have more children in their care than at any other point in the pandemic.
Coronavirus-linked hospitalizations are up 50% from their previous peak at the Arkansas Children’s hospitals in Little Rock and Springdale, the hospitals’ chief clinical officer told CNN, deeming the 24 total pediatric patients housed at their facilities as of Wednesday (which includes seven in intensive care and two on ventilators) the “worst we’ve ever seen it for kids.”
Louisiana has also seen child hospitalizations surge in multiple cities, with the number of patients at Children’s Hospital New Orleans jumping from six at the start of the week to a record 17 on Thursday morning; the facility has paused surgeries to redeploy staff to critical care units.
[...]
In Florida, the trend has been reported in Palm Beach, St. Petersburg, and in Jacksonville, where a top pediatric infectious disease specialist counted a record 20 children currently hospitalized across the city.
[...]
Alabama has hit a new peak state-wide, according to Alabama Hospital Association President Don Williamson, who told The Alabama Reporter that the 32 children currently hospitalized with Covid-19 outpaces the numbers seen even when the state was at its peak in terms of hospitalizations in January.
weepingangel
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