"Whatever you do - do not speculate," he said.
He said the evidence would have a number of strands and all had to line up for the evidence to point to guilt.
"However if none of the strands either collectively or individually… then the relevant element is not proved."
Justice Moore said one inference was that Millane was dead before the accused took intimate photos of her and searched on Google for the Waitakere Ranges and 'hottest fire'.
"There is no direct evidence… but what the Crown says is that when you examine the other evidence, she must have been," he said.
"The Crown says if she was alive… the accused was planning her death."
The defence rejected the Crown position saying Millane and the accused took mutual intimate photographs of each other.
Defence lawyer Ian Brookie said there was "no expert evidence" Millane was dead when the photos were taken and searches were made.
He said the Google searches could be indicative of searches Millane and the accused undertook to plan an outing for her birthday the day after she met.
Brookie said the search for "hottest fire" could mean "anything".
"That evidence is the example of a sort if strand… it is a question for you as to whether it is strong enough on it's own… to support the Crown.
"That is a matter for you, having regard to all of the evidence, because these things cannot be viewed in isolation."
Grace Millane murder trial: What the judge told the jury