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To be clear, the hour 1545 translates to 3:45 pm-- which is the date and time that EMS reportedly arrived at the Reiner residence after receiving the 911 call from RR's roommate. It's also been reported that the bodies were already in rigor mortis when found.
A body gets stiff (rigor mortis) starting around 2-6 hours after death, beginning in small muscles like the face and hands, becoming fully stiff within 8-12 hours, and then gradually relaxing within 24-48 hours as decomposition starts, with factors like temperature significantly affecting the timeline.
If they were in full rigor - 8 to 12 hours - would make it about 2am to 3am that they could have died, as he checked into the hotel at 4am. I have not looked at the autopsy to see if it says "full-rigor" - probably doesn't have that yet....