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I'm not a doctor, but I would be inclined to put dementia, traumatic brain injury, and teenage anger in separate categories. All may present as angry, but I see the cause as mutually exclusive.
Dementia patients are often described as having "word salad". My interpretation is that people with dementia want to communicate, but lack words to accompany thoughts, and therefore become frustrated ... which is interpreted as irrational anger. It's possible that well meaning people presume that dementia clients have no thoughts, since the words don't make sense, but the reality may be loss of vocabulary to communicate thoughts. If people who have lost vocabulary, but retain reasoned thought, are treated as though they have no reasoned thought, frustration and anger is a normal response. It would be like having locked-in syndrome and being treated as though they are imbeciles. It's possible.
Traumatic Brain Injury (TBI) is often described as "brain fog". A symptom of TBI is loss of vocabulary, similar to dementia. It is better understood that TBI vocabulary difficulties do not necessarily imply loss of reason or rational thought. The brain is remarkable in terms of re-wiring itself, so recovery from TBI often includes demonstrated proof that re-jigging vocabulary reveals rational thought. People who experience vocabulary difficulties after TBI, and who are treated as though they lack rational thought, will also demonstrate frustration; interpreted as anger.
Specifically, dementia and TBI have in common: loss of vocabulary, which, depending on the environment, can result in frustration; interpreted as anger.
The child who throws angry tantrums, and who continues to act out with angry tantrums as an adult, is not coping with communication interference. They have vocabulary, but they choose to physically lash out rather than take a deep breath and talk about their feelings. While lashing out as a child, and as an adult, they are aware of others' fearful reaction. I think that is a factor in the decision to lash out rather than verbally communicate.
We know that Nick started with tantrums as a young child, and still had tantrums in his 20s. Those angry outbursts are not caused by drug abuse. They pre-date drug abuse.
Does drug abuse damage the brain? Sure, as does a poor diet, dirty environment, and so on. Does drug abuse pre-dispose angry-murder? Doubt it.
those angry outbursts are not caused by drug abuse? exactly, they're caused by mental illness and possibly negative reactions with psychiatric drugs and/or illegal drugs
IMO he's mentally ill and has been since childhood and that it contributed to his not being able to control his 'angry outbursts'