Thanks for your post, ILW!
From the article:
“I think we can do much better with durability of response,” Anthony Fauci, director of the National Institute of Allergy and Infectious Disease, said in an interview. “Even our best vaccines don’t do a very good job of preventing infection and transmission. They do a good job protecting from severe disease.”
For now, the federal government is hoping to update short-term boosters. Last week
Moderna, maker of one of the most widely used Covid-19 vaccines, said that a tweaked shot targeting the Omicron variant as well as the original strain of the virus worked better in a study than the company’s current jab. Pfizer is expected to release its Omicron-targeted vaccine data any day. The Food and Drug Administration is meeting on June 28 to discuss the best vaccine strategy for targeting variants in the fall.
[...]
To try to get to a more durable Covid vaccine, researchers are drawing from a menu of options. They can make vaccines fight specific variants or a broad range of strains, change the way the shot is delivered to the body, switch the platform for triggering the immune system—or attempt to aim higher, such as preventing infection.
The initial vaccines are delivered through an intramuscular injection, so they do a good job of protecting the lungs from serious infection. A nasal vaccine, however, could be far more effective and perhaps even block infection and transmission because it could block the virus in the nose, throat and mouth, where infections happen, researchers say. The Rockefeller and Bill and Melinda Gates foundations are convening a blue ribbon task force of 11 experts that will make recommendations about the next generation of vaccines to the U.S. government.
[...]
“The vaccines we have are superb against death and severe disease, and only 45% percent of Americans that are eligible have gotten that booster,” said Dr. Poland. “A newer vaccine is highly unlikely to change that.”
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Personal note: DH and I (in our later 70s) were fully vaxxed with Pfizer in early 2021, got the Pfizer booster in October, and chose to have the Moderna booster in May. We've avoided Covid so far but know quite a few people who've had breakthrough infections. We'll see what's next...