Coronavirus COVID-19 - Global Health Pandemic #47

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  • #501
April 15 Drug Shortages

"The Department of Health and Human Services and FEMA "have received requests for assistance from states and localities to fill pharmaceutical shortages," a FEMA spokeswoman told ABC News Tuesday. The agencies "are working closely with our state and local colleagues to ensure that any critical shortfalls are identified."

"A FEMA spokeswoman said supplies are running low for the drugs used to treat and sedate patients who need to be mechanically ventilated. The problem is twofold: There are more patients who need such drugs because of the pandemic and many seriously ill with coronavirus often wind up needing mechanical ventilation for two and three times the number of days typical ventilator patients need the treatment."

"A new fear, the official said, is that a lack of necessary drugs in ambulances could make the treatment of patients in route to hospitals less effective, and potentially more dangerous"

There are still shortages of sedatives, propofol, injectable fentanyl, pain medications, paralytic drugs.

On Friday, I saw on youtube, Michigan Governor Gretchen Whitmer saying she had to write Vice President Pence about their state shortgage

"We are faced with dangerous low levels of medications to safely place patients on ventilators to assure sufficient sedation and pain relief while they remain on ventilators. These medications are just as important as the ventilators themselves."

"One complicating factor: "Injectable drugs take a long time to make," Kistner says. "For instance, there's a 21-day sterility period needed for all injectable drugs. So it's not something simple that you can do overnight."

"At present we're running through anywhere up to 134 bags of fentanyl," says Dr. Shanti Akers, pulmonary and critical care physician at Phoebe Putney. "Pre-COVID that would have lasted us two to three weeks. And now we're running through that quantity in simply a day."

Other Shortages

Other drug shortages have emerged as unintended consequences of the coronavirus. When doctors hoping to prevent the coronavirus from getting airborne inside their facilities avoided nebulizers for patients with respiratory trouble, they inadvertently created shortages of everyday albuterol asthma inhalers in hospitals and retail pharmacies.

-Generic drugs account for about 90 percent of all prescriptions filled in the United States. About 87 percent of the factories making raw pharmaceutical ingredients used in generics are located overseas, with 48 percent in India and China, according to industry estimates. China shut down drug manufacturing facilities during its coronavirus lockdown, but some of those facilities are expected to come back on line in coming weeks and months.

--Nebulizers, Ventolin inhalers, albuterol, chloroquine and hydroxychloroquine

--Severe shortages have prevented some patients who rely on the drugs for approved uses, such as lupus and rheumatoid arthritis, from getting their routine supplies.

--Supply chain has identified 156 drugs that could go into shortage in the next 90 days.

Critical intubation drugs still in short supply in NYC coronavirus fight

U.S. May Get More Ventilators But Run Out Of Medicine For COVID-19 Patients

https://www.washingtonpost.com/business/2020/04/12/drug-ventilator-shortage-coronavirus/

Forgot to add link- Governor of Michigan letter to VP Pence -beginning of video

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  • #502
https://www.washingtonpost.com/news...th-phased-reopening/5e9688d288e0fa101a763033/

BBM
The framework lays out criteria that should be in place before a region can responsibly ease guidelines related to public gatherings: a “genuinely low” number of cases; a “well functioning” monitoring system capable of “promptly detecting” spikes of infections; a public health system able to react robustly to new cases and local health systems that have enough inpatient beds to rapidly scale up in the event of a surge in cases.

This would seem to necessitate ramping up testing and production of personal protective equipment at levels not currently being done."
---------------------------
Reading the 10-page executive summary of the proposed public health response offers a window into the discussions happening inside the government about how to practically and responsibly ease toward reopening. For example, the document says the first priority should be reopening places where children are cared for – including K-12 schools, day cares and summer camps – so parents can return to work."
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  • #503
Why are the processing plants shut down? Have they been hit with Covid like the meat plants have? Just trying to understand what is happening here. Fresh fruit and veggies are being dumped as well?

Meat, vegetables, and dairy (being poured away in rivers) aren't being consumed by restaurants and schools in the same proportions they used to be; and in many cases, "not at all" (all the restaurants who are doing takeout only). If I were paying 100% for my takeout meals (generally rebates, coupons, discounted gift cards), I wouldn't be doing any takeout at all; and I'm still not doing any takeout that doesn't involve heat applied to the food (no salads, etc.).

ETA: As the farmers point out, cows don't stop needing to be milked daily; and crop rotation doesn't stop for an off season either. The udders have to be empty and the fields have to be empty or fallow.
 
  • #504
There has been a post mentioning a cheese program to supply a charity food distributor but can't find it now. I am also wondering why the dairy can't make the milk into Long Life milk (I.e. UHT milk) and give it away also, or make it into long life flavoured milk. It is a terrible waste.

Farmers who raise dairy cows (dairies is what I call them) in the US do not do that kind of processing. At least, no where in the American west and we have quite a bit of dairy product. Even in Wisconsin, they don't.

The place where the cows are fed and milked is not where they make shelf stable milk - that's a couple of processes away. The milk goes into huge tanks and is transported to the UHF (or other) factory. Industrial milk packing.

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^That's New Zealand, so it's all shiny and pretty, but it's the same overall process in the US.

Truck drivers have to be involved, and many workers have to be involved both in getting the milk into the tanker and then, processing it at the plant. We could declare all of these essential workers, but we're already seeing CV higher in truck drivers. Still, if the workers have protection (and the ones at the factory who aren't on the actual production floor - all the bookkeepers, payroll, procurement and logistics people - would need PPE), they could go forward.

But let's face it, these states were not at the ready with PPE at all. So yep, all of the workers in the chain would have to risk CV19 to get that done. Immunity tests much needed. Truckers are saying they need places to eat and go to the restroom without fear of CoVid. And they are entitled to that. Workers in UHF factories would want protection from the truck drivers - so we have to fix that whole chain.

Myself, I just can't handle putting one group of workers at risk until we've gotten PPE and other businesses open. Better sanitation at diesel pumps, instruction for truck drivers on what to do, etc. Remember, CV thrives for a while on metal - and those trucks are metal. Would they need to be sanitized? How often? All of that needs to be worked out - although if people are comfortable with industrial dairy workers (not farmers) getting more CV than the rest of us, they will probably reopen.
 
  • #505
QUESTION: Could Vitamin D deficiency lead to a poor COVID-19 prognosis?
@DrJAshton
: "There are some studies that show an association... they are looking at it right now with COVID-19 as well, but it’s too early for any inclusive data.”

video Vitamin D Association


ABC News Live on Twitter
 
  • #506
that's good news - did you happen to file a return for 2019? I haven't yet. Trying to figure out what the discrepancy could be.
No, that's not it.

Raw milk cannot be sold to the public in many places (no way will I have raw milk in a refrigerator with everything else). Farmers milk cows, but they do not process the milk.

The processing plants are shut down.

Raw Milk Questions and Answers

You'd have to be okay with those risks to use it. Anti-vaxxer types sometimes prefer it (good luck to them), but giving it to poorer people in need of food, who probably already live in crowded conditions, have less access to healthcare and when hospitals are already overwhelmed, would just add to this disaster.

Dairies and farmers feed and milk cows. They do not handle the very strict pasteurization process.
I grew up on fresh cow’s milk that was not pasteurized. However, I wouldn’t drink it now. Can raw cow’s milk be boiled or heated to kill any bacteria?
 
  • #507
QUESTION: Could Vitamin D deficiency lead to a poor COVID-19 prognosis?
@DrJAshton
: "There are some studies that show an association... they are looking at it right now with COVID-19 as well, but it’s too early for any inclusive data.”

video Vitamin D Association


ABC News Live on Twitter

Dr. Campbell, who many of us have followed for months here, speaks often about vitamin D. So does Dr. Seheult from Medcram who is posted here on the links often in more detail.

Here is one from today speaking to low vitamin D levels leads to more reduced levels of immunity, and reduced concentrations of pro-inflammatory cytokines/increased concentrations of anti-inflammatory cytokines (the last two help with lowering opportunities of cytokine storm--> ARDS)

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  • #508
Now, this is interesting. Would this apply to all public buildings? What about federal government buildings? State law vs. Federal law?
Here's what he said: “For example, if you are riding on public transit where it is impossible to maintain social distancing, or walking on a busy sidewalk, you must wear a face covering like a bandana or a mask,” he explained.
 
  • #509
So you'd be okay bringing the bacteria into your house. I guess you're ready, since you've got great hygiene routines. I wouldn't want the bacteria in my car and I don't think the dairies have containers for personal use - you'd have to bring your own (as would everyone else).

I don't know how they could ever distribute to the public, though, without the dairy workers constantly coming into contact with the public. Every single person would need working PPE.

I know Mother Earth News (and at one time, wrote a couple of articles for it - I was a hippie, guess I still am). They are right. If you had a cow, you should learn to do it.

Someone else's barn and cow? I'd have a hard time with it.

I don't really like just plain milk, I want it all to be made into cheese. And that I know I am absolutely terrible at. I tried to make paneer (sort of like cottage cheese) and it was awful.

So far we have been able to find gallons of whole milk. I love whole milk. We all drink it in our home or I cook with it. We normally were getting 2 to 3 gallons a week, and are still able to find plenty of milk in our stores here.

But we also love cheeses of all types. For the first week or so there were shortages of all kinds in grocery stores, but it seems to have evened out now.

Jmho
 
  • #510
Dr. Robert R. Redfield @CDCDirector@@, and at the @WhiteHouse
Task Force are working on a plan to reopen America state by state. This will be a data-driven plan and we will support states through this process.@GMA#COVID19

FULL INTERVIEW: CDC Director Dr. Robert Redfield speaks with @GStephanopoulos on the latest in the coronavirus pandemic battle and plans to re-open the United States. Coronavirus updates: Americans should prepare for 'another battle,' CDC director says

video Dr. Robert R. Redfield on Twitter
 
  • #511
  • #512
Last time my husband went to Costco 1 month, it didn’t have liquid body soap but tons of Kirkland’s large box of bath bar soap. It’s cheap, shaped like Dove and has a great lather.
 
  • #513
The Plan for reopening "Work for America" 1a8a55a6-68f9-4b76-8e02-01779290c1a5.

This type of thinking really bothers me, from the above plan:

"Tightening of mitigation measures will be needed if signs of increased
transmission create strain to the public health or health system capacity are
detected. When indicators signal a return to sufficient public health and health
system capacity, mitigation measures can again be loosened."
--------------------------------------------------------
IE cases & deaths don't matter as long as the hospitals have capacity. It's really hard for me to believe that the CDC and FDA allowed their names to be put on this document.
 
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  • #514
I’m not seeing a viable safe way for family to visit their parents/grandparents in person for a long time. :(
 
  • #515
Wow! That's an amazing story, so glad that she survived and is doing well.

I have a miracle story to share as well. Years ago, my DH became very ill with what turned out to be a serious bacterial infection that led to sepsis and affected his heart. He was hospitalized and then was moved to the CCU and put on full life support. He was on the ventilator for the next 3 1/2 weeks. He had a stroke and had to have dialysis for a while. A very scary time.

Our son came as often as he could (he and his family lived 8 hours away) and was a huge support to me, along with other family members, local friends, and our church. There was a lot of praying going on!

After about 3 weeks the infection was stabilized and he had open-heart surgery to replace his ruined aortic valve. Thank God, the surgery went well. It took another 4 days to wean him off the vent. He had no idea what had been going on for the previous month! He remained in the hospital for about 2 weeks post surgery, then spent another month in a different hospital with an excellent rehabilitation unit.

It was a long haul but he is alive and well today. :)
Sounds so familiar. It’s frightening isn’t it? It changed me. I never cried so much. But God is good to us and I’m so thankful she is alive and well. It’s so good to hear your story. I’m glad he is well too. Thanks for sharing. It made my day!
 
  • #516
  • #517
Meat, vegetables, and dairy (being poured away in rivers) aren't being consumed by restaurants and schools in the same proportions they used to be; and in many cases, "not at all" (all the restaurants who are doing takeout only). If I were paying 100% for my takeout meals (generally rebates, coupons, discounted gift cards), I wouldn't be doing any takeout at all; and I'm still not doing any takeout that doesn't involve heat applied to the food (no salads, etc.).

ETA: As the farmers point out, cows don't stop needing to be milked daily; and crop rotation doesn't stop for an off season either. The udders have to be empty and the fields have to be empty or fallow.
Farmers could dry up a percentage of their cows. Minimize their work load and reduce the high protein feed costs.
 
  • #518
Laundry (two months later)

The Centers for Disease Control and Prevention says COVID-19 can live on cardboard for 24 hours and plastic or metal surfaces for 72 hours, but data has yet to show exactly how that could translate to fabric and linens.

Dr. Todd Ellerin, an infectious disease expert at South Shore Health, told ABC News "the drying part is important as well."

Don't share towels with people if you can avoid it

New Guidelines for Laundromats
Doing Laundry at Home and Someone is Sick
Other Tips and Takeaways


Expert tips for doing laundry to avoid germs amid coronavirus
 
  • #519
The research, published in the journal Nature Medicine, adds to a growing body of evidence showing that seemingly healthy people are spreading the virus.

"We observed the highest viral load in throat swabs at the time of symptom onset, and inferred that infectiousness peaked on or before symptom onset," the researchers wrote.

They found that viral shedding -- when people may be able to infect others -- could begin two to three days before symptoms appeared. The amount of virus given off, though, appeared to decline after people began feeling sick.
Researchers gave a stark warning alongside their research: Because people may be spreading the virus before they show symptoms, public health interventions -- such as contact tracing -- will need to be adjusted.

Not only will investigators need to identify those who were exposed to symptomatic people, but they may also need to look retroactively -- tracing contacts from when people still felt healthy.
People might be most infectious with coronavirus before they show symptoms, study suggests - CNN
 
  • #520
My stimulus payment was automatically deposited into checking account today. Happy to have it.
 
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