Coronavirus COVID-19 - Global Health Pandemic #49

[ColyH]

Agree to disagree.
Police issue arrest warrant for Louisiana pastor who held services despite state order

Two completely different things. Those kids weren't breaking any laws or bothering anyone while this pastor has shown no regard for the law or other people's safety and wonder if he even has a Class B CDL.

 

[Fireflize]

Yes, our "regular/normal" lifestyle is very danaging to everyone and everything. If we would all just sit back and take a good/honest look at what we have turned our world into, with no care for life or our fellow man, maybe we would hang our heads in shame and ask for forgiveness.

Amen, Trident. Our culture was so busy running to and fro! Despite the horror of this pandemic, there are some positive things happening in my family. Home cooked meals with everyone around the table talking. Board games played with children. Homes tidied and fresh. Gardens planted and lawns mowed.

 

[gngr~snap]

The FDA recently changed the testing procedures and type of swabs that are acceptable in order to ramp up testing ability. It was addressed in one of the White House press conferences a few days ago. I looked but couldn't find which presser had it but I found this article that explains the changes: To speed coronavirus testing, FDA greenlights a new type of nasal swab

From the link:

On Thursday [Apr 16, 2020], the Food and Drug Administration announced that it would allow a broader range of swabs to be used in tests, including some made of polyester that should be far easier to manufacture.

[...]

The FDA also announced that US Cotton, the country’s largest manufacturer of cotton swabs, has developed a polyester-based swab fully compatible with Covid-19 testing. The firm plans to manufacture the swabs in “large quantities,” the FDA said.

[...]

The FDA on Thursday [Apr 16, 2020] took other steps that could help speed up diagnostic testing. It now says that a sample can be collected simply by circling the swab in the nose, instead of sticking a longer swab much deeper into the throat through a nostril. That process is deeply uncomfortable and causes patients to sneeze, meaning that health care providers need to be wearing full protective gear.

The agency also said the swab can be done by a patient, instead of by a health care professional. And instead of being stored in viral transport media, a special solution that is in short supply, the FDA also now said that it is OK to use saline solution, which is much more readily available, if necessary.

*Date in brackets added by me for clarity

ETA: It might have been covered in this presser from Apr 16th:

My DH and I were tested with the nasopharyngeal swab and it was very unpleasant to say the least. I was really happy to see they are accepting use of nasal swabs because I don't want to go through that again. MOO.

The test I took wasn't even FDA approved.
Go figure!
Moo

 

[10ofRods]

Excellent! We have to find a new balance as we emerge back into the world. We have to be more thoughtful.

We should give up shaking hands forever. Those of us who prefer more personal space around us, in conversation or in casual encounters, should lead the way to a new norm.

What I see, though, is that as they open up in the county where I was raised, is that a lot of people do think it's business as usual. They're pacing around, coming up near people standing in spaced lines or at drive-through testing sites. They get out of their cars and try to socialize with random other people, but many do not engage or want to talk through their car windows. Sometimes tempers flare.

I think we'll need our security guards to come back to grocery store lots and I think we'll have issues and some pandemonium when L.A. tries to open up. It can take 15 minutes of waiting just to get a parking spot at the store nearest my work, and that's at almost any time of day (up until about midnight or 1 am). People here work all kinds of shift work, shop at all hours, and stores were very crowded.

Now, if they limit the number of people in stores, as they must surely do, I think it's going to be a big shift, with just that one thing.

Meanwhile, grocery store workers, bus drivers, other transit workers have high rates of infection and are over-represented in the death numbers.

 

[margarita25]

Adding this to my new & ever growing <Carona List of Things I Thought I'd Never Read in My Lifetime>

+++Don't be a bare-bottomed farter!

* underline twice*

Hey, don’t forget I talked about wearing butt masks back in January when the clinical term re: APVLD (Aerosol Plumes of Virus -Laden Diarrhea) came to light!

 

[MajorHoople]

Tennessee Brothers Who Hoarded 17,000 Bottles Of Hand Sanitizer Reach Agreement With State

"The Tennessee Attorney General announced a settlement has been reached with two Hixson brothers who admitted to hoarding thousands of bottles of hand sanitizer and other cleaning supplies.

Tennessee Attorney General Herbert H. Slatery III announced the agreement with Matthew Colvin and Noah Colvin to resolve allegations of price gouging in violation of the Tennessee Consumer Protection Act on Tuesday.

On March 14th, the Tennessee Attorney General’s Office began an investigation after learning about alleged price gouging involving emergency and/or medical supplies by Matthew and Noah Colvin during the COVID-19 crisis.

The New York Times reported that after the first coronavirus death was announced in the U.S., the brothers went on a 1300-mile road trip across Tennessee and Kentucky to clean out shelves at local stores.

After being confronted with the allegations, the Colvins cooperated with investigators and surrendered all their supplies, including approximately 17,000 bottles of hand sanitizer, to a Tennessee nonprofit organization."

 

[Sundog]

agree. especially since i take lisinipril. confess, personal bias here.

Finally found an article that explains this well in an April 9, 2020 publication in the Journal of the American Heart Association (JAHA).
https://www.ahajournals.org/doi/10.1161/JAHA.120.016509

Seems that taking ACE Inhibitors and angiotension blockers (ARBs) could be a "double-edged sword" as the scientists write. On the one hand, they cannot rule out that these medications may help to facilitate entry of the virus and virus replication - but on the other hand, once infected, they may be beneficial with regard to pulmonary outcome. So they could potentially (more studies needed) increase infectivity and put a person at a higher risk for infectivity, but once infected the medications could potentially be beneficial.

If the latter is the case, they may be considered (after more studies) as therapeutics for treatment of patients at the stage of pulmonary infection.

Best article I have seen yet in relation to explaining why ACE Inhibitors (such as Lisinopril) and ARBs (such as Losartan) are being looked at as potentially contributing to infection risk, and now as potentially helpful once infected if the infection progresses to the lungs.

 

[Sundog]

YVW. If I hadn't been following Dr. Seheult on MedCram, I would have needed to watch it at least 5 times lol. Hopefully, your friends will have some background to understand. But I really liked how he built on Dr. Seheult's messages to us, and then expounded upon the normal cascade that happens at ACE2, and the interference of the virus at the ACE2 receptors which prevent vasodilation needed, and increases the inflammatory response - the normal response is blocked and rerouted to a dangerous alternate pathway.

This video..... It was a final AHA! moment that I had never really understood COMPLETELY until this video. Glad I found as YouTube algorithm must have sent my way. I only found today in my "home" link at YouTube, as most every day, I just click on my "subscribed" Youtubes. Food for thought, algorithms are good for such. I'm slowing going through his other videos.

In another of his videos, He's on board with the vitamin D need/impact as is Dr. Sehult and Dr. Campbell. (love how Dr. Campbell pronounces vitamin lol). I think many in the scientific community really want the word out about vitamin D, as both Dr. S and Dr. Campbell has said again and again it's so simple and effective, yet Dr. C is continuing to be concerned that no one is speaking to as not politically correct perhaps to speak to that it is more of an issue of a person of color due to their skin color not allowing sufficient production of vitamin D (his words, not mine)

@dixiegirl1035 I just posted a summary of an article in the Journal of the American Heart Association that builds on what Dr. Hansen is saying about the impact of ACE Inhibitor and ARB medications related to coronoavirus infectivity. Good article on April 9, 2020, at
https://www.ahajournals.org/doi/10.1161/JAHA.120.016509

More studies are needed, but it is possible that taking these medications may increase infectivity, but once infected they could possibly lead to beneficial pulmonary outcomes if the virus infection progresses to the lungs.

 

[Sundog]

Great video. I watched it several times, but now am confused about medications for hypertension such as ACE inhibitors (Lisinopril, etc.) and Angiotension blockers (Losartan, etc.). I recall studies and conversations with experts that suggested that ACE inhibitors might be contraindicated in relation to COVID-19. I would like to understand this better, so will continue to do research on this.

Replying to self:
Explained in April 9, 2020 article in Journal of American Heart Association at
https://www.ahajournals.org/doi/10.1161/JAHA.120.016509

 

[10ofRods]

YVW. If I hadn't been following Dr. Seheult on MedCram, I would have needed to watch it at least 5 times lol. Hopefully, your friends will have some background to understand. But I really liked how he built on Dr. Seheult's messages to us, and then expounded upon the normal cascade that happens at ACE2, and the interference of the virus at the ACE2 receptors which prevent vasodilation needed, and increases the inflammatory response - the normal response is blocked and rerouted to a dangerous alternate pathway.

This video..... It was a final AHA! moment that I had never really understood COMPLETELY until this video. Glad I found as YouTube algorithm must have sent my way. I only found today in my "home" link at YouTube, as most every day, I just click on my "subscribed" Youtubes. Food for thought, algorithms are good for such. I'm slowing going through his other videos.

In another of his videos, He's on board with the vitamin D need/impact as is Dr. Sehult and Dr. Campbell. (love how Dr. Campbell pronounces vitamin lol). I think many in the scientific community really want the word out about vitamin D, as both Dr. S and Dr. Campbell has said again and again it's so simple and effective, yet Dr. C is continuing to be concerned that no one is speaking to as not politically correct perhaps to speak to that it is more of an issue of a person of color due to their skin color not allowing sufficient production of vitamin D (his words, not mine)

Thank you for your review of that video - I think it's excellent, also.

The ACE2 issue/vein issue seems to be key to understanding the main difference between CV19 and the other coronaviruses.

It's really hard to take in the information by reading the scientific papers - this video is indeed great.

 

[imstilla.grandma]

National Geographic is celebrating the life and legacy of Doctor Jane Goodall in The Hope, a new 120-minute special, as part of the Earth Day celebrations.

The Hope is the story of a remarkable woman, picking up where the 2017 award-winning film Jane ended.

Doctor Jane Goodall on coronavirus, hope and life after lockdown

We have to learn how to deal with less,” said Goodall, who began her lauded career as a pioneering researcher of chimpanzees in Africa more than 50 years ago. She’s worked for decades on conservation, animal welfare and environmental issues.

Goodall has encouraged young people since 1991 to become stewards in their communities through her Roots & Shoots program, which operates in 60 countries. She normally travels 300 days per year to advocate her endeavors, but these days she’s been staying busy inside her family home in Bournemouth, England, to practice social distancing. She calls it more “exhausting than traveling.”

In a recent interview, the 86-year-old Goodall shared her thoughts on COVID-19, wild animal poaching and her new documentary “Jane Goodall: The Hope,” which premieres Wednesday on National Geographic and Nat Geo WILD, while streamed on Disney Plus and Hulu. The two-hour documentary focuses on her lauded career of transforming the scope of environmentalism.
Jane Goodall talks COVID-19 impact, Nat Geo documentary | Northwest Herald

 

[dixiegirl1035]

Great video. I watched it several times, but now am confused about medications for hypertension such as ACE inhibitors (Lisinopril, etc.) and Angiotension blockers (Losartan, etc.). I recall studies and conversations with experts that suggested that ACE inhibitors might be contraindicated in relation to COVID-19. I would like to understand this better, so will continue to do research on this.

Exactly! He agrees that ACE inhibitors are not good. That is why it took me 2 times to understand, and now I am going through again to take notes to drill into my mind as It is EXTREMELY confusing. Once you asked me, I'm rewinding and rewinding to try to get out of my head to you as I'm not good at ALL in communicating.

Try this.

View this chart from the video at about 7:30 into explaining. The RIGHT side of the cascade is shut down due to the virus landing on and filling the normal cascade of the ACE2 enzyme..they can no longer help which is the normal path for balance with an option for pulmonary arteries to vasodialate and have anti-fibrotic tendencies. These ACE2 are only on the "type 2 aveolar cells". Ok.. with me so far?



OK... so EVERYTHING as an option shifts left as to the only option for vasodilation on the LEFT SIDE of his picture, as the top option for vasodilation on the right is gone due to the virus filling ACE2 receptors.

At 8:03 As this shows, if someone has Ace inhibitors, that SHUTS DOWN ON THE LEFT SIDE ALAO even that option to go further with the Angiotensin I to Angiotension II. STOP. No more option to go further to even get to the options in the next step with Angiotensin II to go in the alternate paths of vasoconstriction/inflammation/fibrosis vs. vasodilator/anti-inflammatory/antifibrosis. The normal cascade options are all fouled up with NO options with an ACE inhibitor.

Having more angiotension II in the lungs vs. angiotension 1-7 causes a crazy reaction in the lungs.

I would go on.... but perhaps review and get to that point, and repost if you want me to go on? I know few here are interested in such, and don't want to bore... but to me, this is fascinating.. and so VERY SAD as that I think this disease is moving so fast, so many folks know this but there is not time to address and share to help others.

Me, I'm STAYING AT HOME as I have a health care directive which states SPECIFICALLY I will not be put on a ventilator.

Lemme know if you want to banter, or if others want me to continue, like this post.

NOTE: I haven't ventured into the bottom left options yet, and how angiotension blockers are good as wanted to ensure on board with what I said here.

MOO MOO MOO @gitana1 who had questions on such earlier

 

[imstilla.grandma]

The new test allows for patients to collect their own samples using Pixel by LabCorp COVID-19 Test home collection kits that they would then mail to a lab for testing, according to an FDA announcement Tuesday.
With a doctor's order, the home collection kits will become available to consumers in most states in the coming weeks, the FDA said.

"Throughout this pandemic we have been facilitating test development to ensure patients access to accurate diagnostics, which includes supporting the development of reliable and accurate at-home sample collection options," FDA Commissioner Dr. Stephen Hahn said in the agency's announcement.

As of Tuesday, more than 788,900 cases of coronavirus have been reported with at least 42,450 deaths, according to Johns Hopkins University.

"The FDA's around-the-clock work since this outbreak began has resulted in the authorization of more than 50 diagnostic tests and engagement with over 350 test developers," Hahn said. "Specifically, for tests that include home sample collection, we worked with LabCorp to ensure the data demonstrated from at-home patient sample collection is as safe and accurate as sample collection at a doctor's office, hospital or other testing site. With this action, there is now a convenient and reliable option for patient sample collection from the comfort and safety of their home."

The LabCorp kit includes a specific Q-tip-style cotton nasal swab for patients to use to collect their sample. The upfront pricing of the test is $119, according to the company's website.

New Covid-19 test allows patients to collect samples at home, send to lab for results - CNN

 

[Sundog]

Exactly! He agrees that ACE inhibitors are not good. That is why it took me 2 times to understand, and now I am going through again to take notes to drill into my mind as It is EXTREMELY confusing. Once you asked me, I'm rewinding and rewinding to try to get out of my head to you as I'm not good at ALL in communicating.

Try this.

View this chart from the video at about 7:30 into explaining. The RIGHT side of the cascade is shut down due to the virus landing on and filling the normal cascade of the ACE2 enzyme..they can no longer help which is the normal path for balance with an option for pulmonary arteries to vasodialate and have anti-fibrotic tendencies. These ACE2 are only on the "type 2 aveolar cells". Ok.. with me so far?

View attachment 243880

OK... so EVERYTHING as an option shifts left as to the only option for vasodilation on the LEFT SIDE of his picture, as the top option for vasodilation on the right is gone due to the virus filling ACE2 receptors.

At 8:03 As this shows, if someone has Ace inhibitors, that SHUTS DOWN ON THE LEFT SIDE ALAO even that option to go further with the Angiotensin I to Angiotension II. STOP. No more option to go further to even get to the options in the next step with Angiotensin II to go in the alternate paths of vasoconstriction/inflammation/fibrosis vs. vasodilator/anti-inflammatory/antifibrosis. The normal cascade options are all fouled up with NO options with an ACE inhibitor.

Having more angiotension II in the lungs vs. angiotension 1-7 causes a crazy reaction in the lungs.

I would go on.... but perhaps review and get to that point, and repost if you want me to go on? I know few here are interested in such, and don't want to bore... but to me, this is fascinating.. and so VERY SAD as that I think this disease is moving so fast, so many folks know this but there is not time to address and share to help others.

Me, I'm STAYING AT HOME as I have a health care directive which states SPECIFICALLY I will not be put on a ventilator.

Lemme know if you want to banter, or if others want me to continue, like this post.

NOTE: I haven't ventured into the bottom left options yet, and how angiotension blockers are good as wanted to ensure on board with what I said here.

MOO MOO MOO @gitana1 who had questions on such earlier

Thanks for all your hard work on this, researching, posting, explaining. I've figured it out now, with help from this article in Journal of American Heart Association scientists' review of research now underway related to ACE inhibitors and ARBs.
https://www.ahajournals.org/doi/10.1161/JAHA.120.016509

 

[HongKongPhooey]

Exactly! He agrees that ACE inhibitors are not good. That is why it took me 2 times to understand, and now I am going through again to take notes to drill into my mind as It is EXTREMELY confusing. Once you asked me, I'm rewinding and rewinding to try to get out of my head to you as I'm not good at ALL in communicating.

Try this.

View this chart from the video at about 7:30 into explaining. The RIGHT side of the cascade is shut down due to the virus landing on and filling the normal cascade of the ACE2 enzyme..they can no longer help which is the normal path for balance with an option for pulmonary arteries to vasodialate and have anti-fibrotic tendencies. These ACE2 are only on the "type 2 aveolar cells". Ok.. with me so far?

View attachment 243880

OK... so EVERYTHING as an option shifts left as to the only option for vasodilation on the LEFT SIDE of his picture, as the top option for vasodilation on the right is gone due to the virus filling ACE2 receptors.

At 8:03 As this shows, if someone has Ace inhibitors, that SHUTS DOWN ON THE LEFT SIDE ALAO even that option to go further with the Angiotensin I to Angiotension II. STOP. No more option to go further to even get to the options in the next step with Angiotensin II to go in the alternate paths of vasoconstriction/inflammation/fibrosis vs. vasodilator/anti-inflammatory/antifibrosis. The normal cascade options are all fouled up with NO options with an ACE inhibitor.

Having more angiotension II in the lungs vs. angiotension 1-7 causes a crazy reaction in the lungs.

I would go on.... but perhaps review and get to that point, and repost if you want me to go on? I know few here are interested in such, and don't want to bore... but to me, this is fascinating.. and so VERY SAD as that I think this disease is moving so fast, so many folks know this but there is not time to address and share to help others.

Me, I'm STAYING AT HOME as I have a health care directive which states SPECIFICALLY I will not be put on a ventilator.

Lemme know if you want to banter, or if others want me to continue, like this post.

NOTE: I haven't ventured into the bottom left options yet, and how angiotension blockers are good as wanted to ensure on board with what I said here.

MOO MOO MOO @gitana1 who had questions on such earlier

I take Losartan and Atenolol, and managed coronavirus without needing hospital care. A month on and some symptoms still linger but I'm not complaining. A little fatigue, sinus issues, brain fog maybe. Getting better by the week.

I wouldnt want people to panic because they take these meds. I'll never know if they worsened my symptoms or not but I'm def still here to tell the tale

 

[Sundog]

Missouri files lawsuit against China

Missouri files suit against China for 'enormous' consequences of coronavirus 'deceit'

 

[katydid23]

Exactly! He agrees that ACE inhibitors are not good. That is why it took me 2 times to understand, and now I am going through again to take notes to drill into my mind as It is EXTREMELY confusing. Once you asked me, I'm rewinding and rewinding to try to get out of my head to you as I'm not good at ALL in communicating.

Try this.

View this chart from the video at about 7:30 into explaining. The RIGHT side of the cascade is shut down due to the virus landing on and filling the normal cascade of the ACE2 enzyme..they can no longer help which is the normal path for balance with an option for pulmonary arteries to vasodialate and have anti-fibrotic tendencies. These ACE2 are only on the "type 2 aveolar cells". Ok.. with me so far?

View attachment 243880

OK... so EVERYTHING as an option shifts left as to the only option for vasodilation on the LEFT SIDE of his picture, as the top option for vasodilation on the right is gone due to the virus filling ACE2 receptors.

At 8:03 As this shows, if someone has Ace inhibitors, that SHUTS DOWN ON THE LEFT SIDE ALAO even that option to go further with the Angiotensin I to Angiotension II. STOP. No more option to go further to even get to the options in the next step with Angiotensin II to go in the alternate paths of vasoconstriction/inflammation/fibrosis vs. vasodilator/anti-inflammatory/antifibrosis. The normal cascade options are all fouled up with NO options with an ACE inhibitor.

Having more angiotension II in the lungs vs. angiotension 1-7 causes a crazy reaction in the lungs.

I would go on.... but perhaps review and get to that point, and repost if you want me to go on? I know few here are interested in such, and don't want to bore... but to me, this is fascinating.. and so VERY SAD as that I think this disease is moving so fast, so many folks know this but there is not time to address and share to help others.

Me, I'm STAYING AT HOME as I have a health care directive which states SPECIFICALLY I will not be put on a ventilator.

Lemme know if you want to banter, or if others want me to continue, like this post.

NOTE: I haven't ventured into the bottom left options yet, and how angiotension blockers are good as wanted to ensure on board with what I said here.

MOO MOO MOO @gitana1 who had questions on such earlier

YIKES......

What a scary situation for people, like us, who are taking these Ace inhibitors.

Many of us would be at risk, by stopping the use of these prescriptions.>>>> At risk of strokes or heart attacks....

But now we are warned that we are at risk by continuing to take these medications?????

 

[katydid23]

I take Losartan and Atenolol, and managed coronavirus without needing hospital care. A month on and some symptoms still linger but I'm not complaining. A little fatigue, sinus issues, brain fog maybe. Getting better by the week.

I wouldnt want people to panic because they take these meds. I'll never know if they worsened my symptoms or not but I'm def still here to tell the tale

That is inspiring to hear. As frightening as it is to hear these medical descriptions of how dangerous these medications might be, in terms of catching CV-----it seems more frightening to stop taking them in the mean time.

 

[Sundog]

California city reports spike in school burglaries since coronavirus stay-at-home order

 

[24Roses]

Iowa news today: April 21: 482 new COVID-19 cases in Iowa, 4 additional deaths 482 new confirmed cases and 4 more have passed. We now have 3,641 confirmed cases and 83 passed. 1,293 have recovered. In her pc today, Governor Reynolds said that 33% of today's new cases were meat packing plants. IMO-I'm guessing that another large amount of today's numbers and recently are also their family members. I have no link to this, but was watching the news today and the Waterloo mayor was on. He said 90% of Black Hawk counties total number involved meat packing (Tyson). BH has a total of 366 confirmed cases right now, but I think that is off by about 8 IMO. Iowa COVID-19 Information IMO-Tyson employees also drive from counties much further away.
https://kwwl.com/2020/04/21/gov-reynolds-launches-new-testing-initiative-test-iowa/ Anyone in Ia. should take the online assesment to determine if they should be tested. 500,000 tests available. Testing sites will be open in various locations around the state. IMO-they will still test those with important occupations first and maybe asymptomatic people at some time. IIRC, this was said in the pc today.
Black Hawk County Board of Health issue proclamation to governor and Tyson requesting shutdown