That may technically be the case in a legal sense, but in real trials jurors pay attention when defense attorneys fail to address a charge specifically, fail to discredit a witness or deflect by accusing someone else without presenting any evidence supporting their accusations. Lori's lawyer can give opening and closing arguments saying Lori has been wrongly accused and someone else has the kids. But if he never shows where the kids are or proves the claims he makes in the opening statements then their defense is going to fail IMHO. The only thing I'm leery of is if corona virus may lead to a sequestered jury (to keep the jury from getting sick, maybe) and if that happens then we could have another Casey Anthony verdict due to extreme life pressure on the jury-- it's bad enough being sequestered but to be sequestered and not know if your family members who are quarantined at home are still alive and well might be a bridge too far. Hopefully the pandemic will be over by the time this comes to trial.
As for your second sentence about there being no evidence of the kids being harmed, I disagree. The prosecution can show that Lori has not had any contact with her children since at least November 1st when she was under surveillance by LE. She hasn't made any arrangements for her children to receive food, medical care nor other basic necessities, nor has she paid anyone else to take care of her children's needs. Evidence will likely show that she has continued to receive and withdraw payments from SS that were supposed to go to her children's needs but she spent the money on herself and her new husband instead. And no evidence of the money ever going to her children's care. Then we will have testimony that she lied about Tylee being dead years ago. And her new husband lied to his family members and Tammy's family members saying Lori doesn't have any minor children and is an "empty nester". The lies told about the children by Lori, Chad and even Alex and then the attempts to get their friend MG to lie to police and say she had JJ with her when she hadn't seen him in months, plus Lori and Chad fleeing to Hawaii after the welfare check will be used as evidence that the children have likely been harmed as well. They were given several opportunities to present the children or even to arrange a facetime with the children to police and they didn't do that. Instead they fled and they hid in Hawaii. Lori's actions at every turn of the investigation show her children are in grave danger, if not already harmed.
All that said, while it's my opinion the children have been harmed, the prosecution will not be trying to prove she harmed the children yet since there are no murder charges and no abuse charges. The prosecution only has to prove felony desertion and non-support plus evidence of the other misdemeanor charges (solicitation, obstruction & contempt). MOO.
Lori current charges:
Desertion and Nonsupport of Dependent Child Under 18 YOA, I18-401(1), Felony on 9/23/2019
Desertion and Nonsupport of Dependent Child Under 18 YOA, I18-401(1), Felony on 9/08/2019
Arrests & Seizures-Resisting or Obstructing Officers, I18-705, Misdemeanor, 11/26/2019
Criminal Solicitation to Commit a Crime, I18-2001 {M}, Misdemeanor, 11/26/2019
Contempt of Court-Criminal-Willful disobedience or court process or order, 18-1801(4), 1/30/2020