I'm local to this one. Thankfully the community is going a good job of getting Eliotte's face out there on the news, facebook, and fliers.
I took a walk around the area she was last seen. This immediate area used to all be industrial years ago, and now it's a mix of nice new businesses and ugly stuff a block away. Where she was last seen is just about the end of the nice part.
She was very close to the Mississippi river, but she had just walked past the places you'd go to get to river itself. IMHO, she could not have made it to the river without being on camera, or climbing over a fence and some ugly stuff. Still, there are crews searching the river, which is good.
There are two hotels right there, and she's heading right toward one of them - Courtyard by Marriott. It looks like it's possible to walk past the hotel or into their parking lot without being on camera. I'm assuming their front entrance has a camera.
One block to the east is the other hotel, Fairfield Inn. The way she's walking is not the natural way to get there. She'd basically be walking on one really unwelcoming block, to come up to the back of the hotel. There is a side entrance, and I didn't see any cameras anywhere along here including that entrance.
The only other thing right here is the Cass Street Bridge, which is our biggest landmark (you would not need to be using maps on your phone to find it.) There is a stairway leading up to the bridge. The stairway itself doesn't seem to have cameras, but I'm pretty sure the top of the bridge does.
One other note: bars legally have to close by 2:30am here. She was last seen at 3:22am, so almost an hour later.
Keepng any further speculation to myself, as I'm not sure it would be allowed or helpful.
Everything MOO: my opinion only / my local observations only