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Now I really am wondering if the "flu" he had been battling for weeks was really him trying to wean himself off the pain meds. Withdrawal from opiates makes one a horrible mess. See below for a link for symptoms. People who don't realize they are physically dependent can actually think they have the flu. Maybe he had decided to go to rehab, so he decided to have one last night of relief, knowing what was to come. Maybe he had weaned himself down somewhat and went back to his old dose, which was now an overdose. Like Cory Monteith did. This is so, so sad. He probably had a valid reason for going on pain meds. But they are tricky.
http://www.healthline.com/health/opiate-withdrawal#Treatment5
http://www.healthline.com/health/opiate-withdrawal#Treatment5