09:31 BST: Police receive reports of a car being driven towards members of the public outside Heaton Park Hebrew Congregation Synagogue, and a man being stabbed.
09:37: Greater Manchester Police (GMP) declare Operation Plato -
which we explain here - and a major incident.
09:38: Shots are fired by GMP firearms officers. They later say a man - thought to be the suspect - has been shot and is believed to be dead, but because of "suspicious items on his person" they aren't able to confirm his condition.
09:41: Paramedics arrive at the scene and tend to injured members of the public. Police initially say four people are thought to have been injured.
10:45: Images begin appearing from the scene, with police and ambulance workers seen wearing helmets and stab proof vests, and a bomb disposal robot.
11:08: Prime Minister Keir Starmer condemns the attack and says the fact it's taken place on Yom Kippur, the holiest day in the Jewish calendar, "makes it all the more horrific".
12:11: Police confirm two people have died and a third person - believed to be the suspect - is also presumed dead. Three more people are in a serious condition, GMP add.
Police declare 'Operation Plato' - what is that?
BBC News
Police said they declared "Plato" moments after first hearing about the incident.
Operation Plato is a set of responses by the emergency services to large-scale incidents including "marauding terrorist attacks".
When police declare Operation Plato, the other emergency services such as the ambulance service then have protocols that they follow.
For example NHS trusts will activate their major incident plans.
The attacker was shot dead at the scene by armed officers; police later make two other arrests. Four victims remain in hospital.
www.bbc.co.uk