WY - Tranyelle Harshman, 32, shot all four kids and then herself, 4 dead, Byron, February 10, 2025

[Mauig’ma]

That is interesting. Ketamine. Isn’t that the same drug Matthew Perry had in his system? I have heard of mental health practices using Ketamine with therapy, but I am wary of it. (Great, you can order it online now).

What Is Ketamine? How It Works and May Help With Severe Depression

Is ketamine a treatment for depression? What are the risks? Learn about the uses, benefits, and side effects of ketamine.

www.webmd.com

I’ve done Ketamine numerous times intravenously for major depressive disorder and worked tremendously for me anyways. I did have a treatment stopped due to going into a K-hole. Blood pressure went high. Frightening but ended up fine. In my experience

 

[mickey2942]

I’ve done Ketamine numerous times intravenously for major depressive disorder and worked tremendously for me anyways. I did have a treatment stopped due to going into a K-hole. Blood pressure went high. Frightening but ended up fine. In my experience

Interesting. I haven't read any studies on it, but definitely, if someone is taking it therapeutically they should be under close mental health supervision. Like almost daily check-ins, no reason not to with telehealth available almost every where.

 

[airportwoman]

Thanks for the update.

Matthew Perry's ketamine source, from what I've always heard, was probably gray-market if not outright black-market. It was like Michael Jackson and propofol - if they've got the money, they can get anything if they can find a willing seller.

 

[BeginnerSleuther]

Interesting. I haven't read any studies on it, but definitely, if someone is taking it therapeutically they should be under close mental health supervision. Like almost daily check-ins, no reason not to with telehealth available almost every where.

Well, there's plenty of reason not to be. There aren't enough mental health providers for some of them to be doing daily visits with anyone. But also, it's not clinically indicated to have daily visits if someone is taking Ketamine.

This is a media story. These things happen and in desperate need to understand it, the media latches on to whatever mental health drugs the person was taking.

Klonopin is a very common benzodiazapine. I have had exactly 0 patients with any of the side effects mentioned in the article. It's like when you take Tylenol and the potential side effects are hearing loss, high blood pressure, collapsed lungs, and liver failure. Do any of us know someone who experienced any of those from regular non-daily use of Tylenol? My guess is no.

Benadryl, which is a popular over-the-counter medication has side effects of heart arrhythmias, seizures, blurred vision, hallucinations, agitation, confusion, and delirium. But again, I doubt any of us know people who've experienced those symptoms.

The media loves to make psych meds the scapegoat. I very seriously doubt that her medications played a role in this. It was most likely the illness itself. In my experience, postpartum depression and postpartum psychosis are far more deadly and far more likely to cause homicide or murder/suicide than the medication used to treat it.

 

[JoeFromLB]

Anecdotal, but I found out I'm violently allergic to Benadryl. My mouth and throat went so dry that I had a lot of trouble catching a breath. Very scary.
Also, speaking of antidepressants, my doctor prescribed Trazadone for terrible insomnia and I thought I was going to die. The most intense anxiety I've ever experienced. I survived that night without jumping out a window and threw out the rest of the bottle. No more drugs. I just deal with things naturally and life is good.

 

[airportwoman]

Anecdotal, but I found out I'm violently allergic to Benadryl. My mouth and throat went so dry that I had a lot of trouble catching a breath. Very scary.
Also, speaking of antidepressants, my doctor prescribed Trazadone for terrible insomnia and I thought I was going to die. The most intense anxiety I've ever experienced. I survived that night without jumping out a window and threw out the rest of the bottle. No more drugs. I just deal with things naturally and life is good.

Are you sure you were allergic to the diphenhydramine itself, and not one of the excipient ingredients - dye, binder, etc.? I realize you probably don't want to find out the hard way.

 

[Muddy K]

Below was clipped by me from the Daily Mail UK article - Daily Mail UK Covers Toxicology Report

Their toxicology reports, as first reviewed by local news outlet, Cowboy State Daily, revealed that the children who died at the scene had 'unusual large amounts of Propanolol – beta-blocker – and Diphenhydramine – antihistamine which causes drowsiness – in their systems.'

Diphenhydramine is a key ingredient in the brand-name allergy drug, Benadryl. Propranolol is a prescription beta-blocker that can treat high blood pressure, chest pain, migraines, and tremors.

The article makes no mention either way, but I wonder whether this desperate woman drugged the children that morning, in a tortured act of "kindness," if you will, or other ill-reasoned attempt to spare them from realizing what was about to happen.

I can't help but contrast Tranyelle Harshman with Lindsay Clancy - Lindsay Clancy Thread. I see a couple of major differences. In both hauntingly sad cases, the children lost their lives, but Lindsay Clancy chose to strangle her children. If they were drugged in advance, I have not seen that reported. Strangulation is direct physical assault. I can't grasp how she could stand to do it.

Tranyelle shot her children. There is some illusion of distance with a gun, IMO.

Lindsay Clancy threw herself out of a second-storey window, resulting in permanent paralysis but no death - though she may have intended to kill herself. Tranyelle Harshman shot herself, and it's hard for me to see how she would have intended that act to be anything other than final.

I just keep thinking about these troubling cases. IMO, there is such a fine line to walk here between compassion and horror, empathy and anger.

 

[DS2021]

The article makes no mention either way, but I wonder whether this desperate woman drugged the children that morning, in a tortured act of "kindness," if you will, or other ill-reasoned attempt to spare them from realizing what was about to happen.

Or she was mentally unable to take care of them so she gave them benadryl so they'd sleep.

 

[mickey2942]

Or she was mentally unable to take care of them so she gave them benadryl so they'd sleep.

So many parents, and even daycares do this! Don't forget Casey Anthony, "Zanny, the Nanny". Everyone knew what that meant!