This bugged me, too... Sounds like something he possibly pointed out to her as well. What's also been bugging me is the clothing description on the poster: "Workout clothes (stretchy pants and a tank top)"
Number one, that's not very specific (no color, etc.). Number 2, if she had been gone to visit a friend and her husband hadn't actually seen her (which is what it all sounds like to me) since at least the day before I would think she would have changed clothes and I seriously doubt she would have packed nothing but workout clothes as the pics I've seen don't suggest that she wore workout clothes all the time.
Also, what was she wearing when the Dunkin Donuts person saw her (that she told she felt she was being followed) and what was she wearing when the witness(es) at the Comfort Inn saw her arguing with the 2 (or 3) men?