Assuming all the RSOs have DNA on file, then an unknown sample would exclude them. But I don't know for sure that all RSOs in Indiana and every other state for that matter have DNA on file. Some may not. I think it varies by state.
I asked that question 2 or 3 threads ago and it was confirmed to me that all Indiana RSO's do indeed have Dna on file... so yes if we find out that they are searching the homes of registered sex offenders then they clearly have no dna evidence...which IMO is unlikely... my guess is they didn't find it until late last week and are still waiting for results... clearly speculation on my part.