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I'm thinking this child was abused and died from neglect in a care facility. She had a mild case of spinal bifada. Maybe her parents turned her over to the state because they were unable to care for her. I'm not sure if a mild case of spinal bifada would be disabling enough that she needed to be in a care facility. I don't know if her condition was bad enough for a wheelchair, etc.
I think her parents were dead or in prison possibly crack addicts from Chicago so she was left at a orphanage/care facility or with custodians. She was not neglected at the time of her death though and it's uncertain wether the spinal bifada was a issue for her. A possible scenario is she either ran away from that place and met the wrong persons or someone close to her, perhaps even from the care facility introduced her to her killer. She was raped and murdered as we know not neglected to death. She was also not from the st Louis area. My guess she's from Chicago.