Multisystem inflammatory syndrome in children (MIS-C and COVID-19)

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“The Washington state Department of Health says it remains important for children to take the same precautions as adults, including wearing masks, hand washing and social distancing, in part because of a syndrome linked to COVID-19 in children.

There now have been 15 cases of multisystem inflammatory syndrome in children in Washington state, including two in Franklin County and four in Yakima County, but none in Benton County.

“While rare, MIS-C is a serious complication that appears to be associated with COVID-19. Children who suffer from MIS-C can become critically ill and some can even die,” said Dr. Kathy Lofy, Washington state health officer.

None of the cases in Washington state have resulted in the death of a child.

MIS-C causes inflammation in different body parts, including the heart, lungs, kidneys, brain, skin, eyes or gastrointestinal organs.

Children with MIS-C may have a fever and symptoms such as abdominal pain, vomiting, diarrhea, neck pain, rash and bloodshot eyes.“


Tri-Cities hits a sad milestone for COVID cases. It was not a good weekend
Oct. 26, 2020

 

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“Multisystem Inflammatory Syndrome in Children (MIS-C)

Each week, the California Department of Public Health updates the number of cases of Multisystem Inflammatory Syndrome in Children (MIS-C) reported in the state. As of October 19, 115 cases of MIS-C have been reported statewide. To protect patient confidentiality in counties with fewer than 11 cases, we are not providing total counts at this time.“

California State Officials Announce Latest COVID-19 Facts for Sunday Afternoon, October 25 – 898,029 (Up 5,219 Over Saturday's Report) Confirmed Cases, 17,345 Deaths (Up 34 Over Saturday's Report)

 

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Local Family Struggles With Boy's MIS-C Diagnosis
Oct. 16, 2020

 

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Lubbock Teenager Survives Serious Post COVID-19 Sickness
5 days ago

 

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Dangerous COVID-19 syndrome first seen in kids also strikes adults
Oct. 26, 2020

 

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MIS-C: Symptoms and how COVID-19 affects children amid back to school
Aug. 31, 2020

 

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What if MIS-C is just COVID-19 for children?
July 30, 2020

 

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Multisystem inflammatory syndrome in children: A systematic review
Sept. 1, 2020

 

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11 Washington state kids sickened by serious inflammatory illness linked to COVID
Aug. 7, 2020

MIS-C: Symptoms and how COVID-19 affects children amid back to school
Aug. 31, 2020

Multisystem inflammatory syndrome in children: A systematic review
Sept. 1, 2020

Post-COVID syndrome severely damages children’s hearts; 'immense inflammation’ causing cardiac blood vessel dilation - UT Health San Antonio
Sept. 4, 2020 (link courtesy of @ZoriahNZ)

Ballad Health seeing increase in pediatric COVID-19, MIS-C cases | WJHL | Tri-Cities News & Weather
September 28, 2020

Kids’ Severe COVID-19 Reaction Bears Unique Immune Signature
Sept. 29, 2020

Four Coastal Bend children diagnosed with MIS-C after contracting COVID-19
Sept 30, 2020

BRPROUD/Confirmed cases of MIS-C go up again in Louisiana
Oct. 1, 2020

NEW: 3 COVID-19 deaths reported statewide; health district reports new MIS-C case | KLAS
Oct. 1, 2020

CDC identifies new Covid-19 syndrome in adults similar to MIS-C in kids - CNN
Oct. 2, 2020

‘We don’t know why this happens’: When to suspect MIS-C in a patient
Oct. 6, 2020

Cell Studies on MIS-C, Acute SARS-CoV-2 Adaptive Immunity, Maternal Microbe Transplant
Oct. 7, 2020

Mayo Clinic / Updated Oct 8:
Multisystem inflammatory syndrome in children (MIS-C) and COVID-19 - Symptoms and causes

Area teenager is first in state to die from MIS-C, a complication caused by COVID-19
Oct. 8, 2020

Another Child Diagnosed With Covid-Related 'MIS-C' Illness In LA County
Oct. 13, 2020

Idaho teen diagnosed with MIS-C hospitalized, awaiting heart transplant in Salt Lake City | ktvb.com
Oct. 13, 2020

MIS-C Detection: BARDA Invests in Rapid Diagnostic for Pediatric Complication of SARS-CoV-2 | Global Biodefense
Oct. 15, 2020

Multisystem Inflammatory Syndrome in Children (MIS-C) / CDC
Oct. 15, 2020

BRPROUD/Confirmed cases of MIS-C continue to rise in Louisiana
Oct. 15, 2020

Canada / BC:
First case of MIS-C confirmed in B.C. child, health officials say
Oct. 15, 2020

B.C. officials confirm first case of MIS-C in the province | Watch News Videos Online
Oct. 15, 2020

BARDA taps Beckman Coulter to develop a blood test for MIS-C, the severe childhood illness linked to COVID-19
Oct. 16, 2020

NEW: 716 cases, 9 deaths statewide, another MIS-C diagnosis in Clark County | KLAS
Oct. 16, 2020

Local Family Struggles With Boy's MIS-C Diagnosis
Oct. 16, 2020

National Geographic
‘Super antigens’ tied to mysterious COVID-19 syndrome in children
Oct. 16, 2020

Beckman Coulter, BARDA partner for rapid detection of MIS-C
Oct. 16, 2020

A rare Covid-19 complication was reported in children. Now, it's showing up in adults. (Link courtesy via @BetteDavisEyes)
Oct. 16, 2020

Colorado resident, 20, with ‘mild’ coronavirus case later develops rare condition: officials
The patient required hospitalization and intensive care
Oct. 19, 2020

Multisystem Inflammatory Syndrome in Children in the United States / NEJM / Oct. 21, 2020
https://www.nejm.org/doi/full/10.1056/NEJMc2026136

Lubbock Teenager Survives Serious Post COVID-19 Sickness
Oct. 21, 2020

15 cases of rare child illness linked to COVID-19 reported in Washington | king5.com
Oct. 22, 2020

Study highlights overlapping symptoms of MIS-C, other illnesses
Oct. 22, 2020

County reports 2 addition MIS-C cases in children; SCV sees 55 new COVID-19 cases
Oct. 23, 2020

Dangerous COVID-19 syndrome first seen in kids also strikes adults
Oct. 26, 2020

“There now have been 15 cases of multisystem inflammatory syndrome in children in Washington state, including two in Franklin County and four in Yakima County, but none in Benton County.”
Oct. 26, 2020

Wichita Doctors Diagnose First Case Of MIS-C, A Condition That Stems From COVID-19
Oct. 26, 2020

Child Covid-19 cases increased 14% says AAP, with close to 800,000 US kids infected - CNN
Oct 27, 2020
(Link courtesy of @ZoriahNZ)


More articles / May 1 - August 7, 2020

WHO / Multisystem inflammatory syndrome in children and adolescents temporally related to COVID-19
May 15
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Worrisome details noted in kids with COVID inflammatory syndrome
June 29, 2020
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Studies find nearly 300 kids with inflammatory condition tied to Covid-19
June 29, 2020
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https://www.miamiherald.com/news/coronavirus/article243892967.html
July 1
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"It's out there and it's occurring:" Clark County child has COVID related MIS-C
July 6
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The Latest on the Mysterious Inflammatory Syndrome in Children
July 7
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Cardiac MRI Aids Evaluation of Children With Multisystem Inflammatory Syndrome (MIS-C) Associated With COVID-19
July 9
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Intensive care admissions of children with paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS) in the UK: a multicentre observational study
July 9
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First case of Multisystem Inflammatory Syndrome in children reported in Rappahannock Area Health District - Fredericksburg Today
July 10
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Multisystem inflammatory syndrome in children associated with COVID-19
July 13
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Serology distinguishes children with MIS-C associated with COVID-19
July 13
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Doctors warn of rise in serious condition in Arizona kids from COVID-19 exposure
July 14
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Why Doctors Keep Monitoring Children Who Recover From Mysterious COVID-Linked Illness
July 15
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AAP issues guidance on multisystem inflammatory syndrome in children
July 16
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CDC: 71% of MIS-C patients Hispanic or Black
July 16
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Identification of children at high-risk for MIS-C
July 17
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Wisconsin coronavirus: 900 more COVID-19 cases, six kids with MIS-C
July 17
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Friday COVID-19 Roundup: 15 Cases of MIS-C in Kids, 2,885 New COVID Cases in L.A. County - SCVNews.com
July 17
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INTERVIEW: The MIS-C complication with children and COVID-19
July 17
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AAP issues interim guidance for MIS-C
July 21
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COVID-19’s Kawasaki-Like MIS-C Diagnosis Is Cropping Up in Adults
July 22
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https://www.nejm.org/doi/full/10.1056/NEJMoa2021680
July 23, 2020

Multisystem Inflammatory Syndrome in U.S. Children and Adolescents
List of authors.

• Leora R. Feldstein, Ph.D.,
• Erica B. Rose, Ph.D.,
• Steven M. Horwitz, M.D.,
• Jennifer P. Collins, M.D.,
• for the Overcoming COVID-19 Investigators, and the CDC COVID-19 Response Team*

July 23, 2020
N Engl J Med 2020; 383:334-346
DOI: 10.1056/NEJMoa2021680
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2 Colorado children die from coronavirus-related disease
July 23

2 Children In Colorado Die From MIS-C, Mysterious Syndrome Linked To Coronavirus
July 23

2 children have died in Colorado of MISC-C, rare syndrome tied to COVID-19 – The Denver Post
July 23

2 Colorado deaths attributed to multi-system inflammatory syndrome, the child disorder linked to coronavirus
July 23

“Dominguez cautioned that the CDC is casting a wide net as it investigates MIS-C and that some patients who are simply battling coronavirus and not necessarily the disorder in Colorado may be lumped together. He said, for instance, that Children’s had a child who died who met the CDC’s broad definition of MIS-C cases but that they were “somewhat atypical of kids that we are seeing with MIS-C.”

“There is a clinical definition and there is an epidemiological definition,” he said. “The CDC’s definition is pretty broad. There’s probably a few kids that meet the definition that probably have something that’s slightly different than what we’re currently thinking about what MIS-C probably is.”

Gov. Jared Polis and his public health team have encouraged Colorado parents to stay vigilant in case their children start showing signs of the disorder.“
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'He's hurting': Mom of teen with MIS-C details 2 month-long recovery
July 23
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SC announces 2 more cases of MIS-C in children; 1,538 new cases of COVID-19, 49 additional deaths
July 23
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Beaufort Co. health officials speak about MIS-C, COVID-19 cases
July 24
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Nearly 2,000 additional coronavirus cases; 1 more case of MIS-C reported Friday
July 24
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8-year-old Florida boy hospitalized with illness caused by COVID
July 25
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73-percent of kids with mis-c were previously healthy, CDC says | KAMR - MyHighPlains.com
July 27
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Cuomo on MIS-C: “The more you look for it, the more you find it"
July 28
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Higher COVID-19 rates seen in Black and Hispanic kids
July 29
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MIS-C different from severe COVID-19 in children: Findings show that MIS-C is a post-infectious syndrome distinct from Kawasaki disease and may help guide treatment decisions
July 30

CHOP researchers identify lab profiles that differentiate MIS-C from COVID-19 in children
July 30

CHOP Researchers Identify Lab Profiles that Differentiate MIS-C from COVID-19 in Children
July 30
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Upper Keys boy battling rare syndrome linked to COVID-19 - Florida Keys Weekly Newspapers
July 30
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Upstate child diagnosed with MIS-C associated with COVID-19, DHEC reports
July 31
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One new MIS-C case reported in SC, total now at five
July 31
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DHEC: 6th SC child diagnosed with MIS-C - ABC Columbia
July 31
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MIS-C's Impact on Children
July 31
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Duval County 16-year-old has rare disease linked to COVID-19
July 31
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MIS-C: Doctors make progress on COVID-related illness affecting kids
Aug 2
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Local mother speaks out after son was diagnosed with Mis-C - KYMA
Aug 3
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As South Lake Tahoe boy fights for his life, dad wants officials to take COVID-19 more seriously
Aug 3
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Florida Keys boy leaves hospital after battling MIS-C, an effect of COVID-19
August 4, 2020
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Tribe issues MIS-C warning for children
Aug 5
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‘Be Strong:' 8-Year-Old Beats COVID-19, MIS-C Complications
Aug 6

Coronavirus News: 8-year-old boy who survived mystery illness linked to COVID-19 honored by hospital
Aug 6
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LDH reports 14 new cases, third child death from COVID-19-related illness MIS-C | WNTZ - cenlanow.com
Aug 6
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Goodyear baby survives rare illness linked to COVID-19
Aug 6
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Look for Neurologic Symptoms in Children with Multisystem... : Neurology Today
Aug 6
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Liam's road to recovery - KYMA
Aug 6
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Local teen beats Covid-19 and post viral syndrome
Aug 7

 

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Pfizer's Covid-19 vaccine trial moves into kids as young as 12 - CNN
This 12-year-old is happy to be testing a Covid-19 vaccine

 

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Child in Ada County hospitalized with MIS-C
Oct. 30, 2020

 

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CDC webinar:
Webinar May 19, 2020 - Multisystem Inflammatory Syndrome in Children (MIS-C) Associated with Coronavirus Disease 2019 (COVID-19)

 

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Cases of Covid-19 in children on rise in the US, with highest 1-week spike yet - CNN

Uggggh new this was coming. Damnit.

eta
“While cases of severe illness due to Covid-19 appears to be rare among children, severe illness has been reported, most often in infants less than a year.
When children did need to be hospitalized, the CDC found, one in three needed to be treated in the intensive care unit -- the same rate as for adults.“

 

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For reference:

Children and COVID-19: State Data Report
A joint report from the American Academy of Pediatrics and the Children’s Hospital Association
Summary of publicly reported data from 49 states, NYC, DC, PR, and GU Version: 10/29/20
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Coronavirus updates: More than 61K kids got COVID-19 last week, another US record; CDC says Americans sick with virus can vote in person

 

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Note: There are many search results for videos re: MIS-C, including webinars, medical lectures, etc. which have not been posted, but are available online.

 

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Texas kindergartner dies from COVID-19 | KTAB - BigCountryHomepage.com
Nov. 4, 2020

MIS- C not mentioned specifically, but article says “This will be updated as more information is released.“

 

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COVID-19 and kids: Experts explain why cases of rare MIS-C are rising
Nov. 5, 2020

“Just days after the American Academy of Pediatrics revealed that cases of COVID-19 in children are at their highest since the pandemic began, reports are trickling in of an uptick in diagnoses of multi-system inflammatory syndrome in children (MIS-C), a serious complication of the virus.“

[...]

““This is very sobering news, but I’m afraid it was expected,” Dr. William Schaffner, an infectious disease specialist and professor at the Vanderbilt University School of Medicine, tells Yahoo Life. “After all, we’re having widespread transmission of the COVID virus throughout most of the country now, and it’s one of the consequences. The more COVID-19 we have out there, the more cases of MIS-C we’ll see.”

“It’s not surprising given increasing number of cases,” Dr. Richard Watkins, an infectious disease physician in Akron, Ohio, and a professor of medicine at the Northeast Ohio Medical University, tells Yahoo Life. However, he stresses, MIS-C is “still rare.”

Dr. Daniel Ganjian, a pediatrician at Providence Saint John’s Health Center in Santa Monica, Calif., tells Yahoo Life that the increase in cases is “expected,” but, he points out, “it’s not growing exponentially, where we’re worried that it’s going out of control.”“

 

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Douglas County confirms new case of MIS-C, reports 381 new cases
Nov. 4, 2020

“OMAHA, Neb. — A new case of Multisystem Inflammatory Syndrome in Children (MIS-C) has been confirmed in Douglas County.

Two cases were reported in June, according to the Douglas County Health Department (DCHD).

The DCHD said the third is currently at Children’s Hospital after being admitted on Nov. 1.

The health department said the patient is under 10 years old, tested positive for COVID-19 antibodies and has no comorbidities.“

 

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Pasadena Reports 1st Case of Rare But Serious Coronavirus-Related MIS-C in a Child – Pasadena Now
Nov. 4, 2020

“Pasadena health officials on Wednesday reported the first known case in the city of a “rare but serious” complication affecting young COVID-19 patients known as multisystem inflammatory syndrome in children, or MIS-C.

A total of 43 cases of MIS-C have been documented countywide since the onset of the pandemic, according to the Los Angeles County Department of Public Health. No deaths linked to the condition have been reported.“

[...]

““MIS-C is a rare but serious complication associated with COVID-19. It’s a condition where different body parts, such as the heart, lungs, kidneys, brain, skin, eyes, or gastrointestinal organs, become inflamed,” according to Pasadena Public Health Department Director Dr. Ying-Ying Goh.

“We do not yet know what causes MIS-C, but it’s another unfortunate reminder of the seriousness of the COVID-19 pandemic,” Goh said in a written statement. “The best way to protect your child is by taking actions to prevent your child and the entire household from getting the virus that causes COVID-19.”“

 

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Specialists clarify why instances of uncommon MIS-C are rising | KYR News
Nov. 5, 2020

“This week, Nebraska’s Douglas County Health Department reported its third case of MIS-C since June. Additionally this week, the Louisiana Department of Health stated that a fifth baby within the state has died of MIS-C. Circumstances proceed to crop up throughout the nation — Pasadena, Calif., simply noticed its first case of MIS-C, as did Idaho’s Ada County. And there are lots of extra.”

[...]

“As of Oct. 30, there have been 1,163 reported instances of MIS-C within the U.S., and 20 deaths from the syndrome, in response to CDC data. Most instances of MIS-C are in youngsters youthful than 14, and greater than 75 % of reported instances have occurred in youngsters who’re Hispanic or Latino, the CDC says.“