Suicide PreventionPI: Robert Freedman, Research DirectorVA Therapeutic Development Team: Robert Freedman MD, Sherry Leonard PhD, Karen E. Stevens PhD, Laura Martin PhD, Jason Tregellas PhD, Josette Harris PhD, and Lynn Fenton, MDDescription: There are two problems in the prevention of suicide: (1) detection of individuals who are at risk, and (2) treatment to prevent suicides. Most of the major risk factors for suicide in young people, the focus of the VISN19 MIRECC's mission, are known: male sex, exposure to firearms, history of violence, mental illness, cigarette smoking, and other substance abuse. Work by VISN19 MIRECC investigators found that traumatic brain injury and chronic pain are two additional risk factors. Note that many of the risk factors-exposure to firearms and violence, for example-are common problems of combat Veterans that we cannot reverse.Keywords: Suicide, Clozapine, SerotoninLocation: Denver